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We review the various lesions encountered in the parotid gland associated with HIV infection and propose guidelines for the management of a chronic parotid swelling in this setting. Lymphoepithelial cysts is the main diagnosis of parotid masses prese

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ba4799d08dc09d10a9f4823c7e247514
https://pubmed.ncbi.nlm.nih.gov/16775998

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Field cancerisation and polyclonal p53 mutation in the upper aero-digestive tract

Autor: Jean-Michel Flaman, Bron L, Fontolliet C, Philippe Monnier, Thierry Frebourg, Richard Iggo, Francois Waridel, A Estreicher

Publikováno v: Oncogene. 14(2)

Field cancerisation of the aerodigestive tract is caused by chronic exposure to alcohol and tobacco, but the nature of the genetic alterations preceding overt malignancy is unknown. To identify potential field changes we have used a functional assay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6649795ff29b7f232d3708b16ae6177
https://pubmed.ncbi.nlm.nih.gov/9010218

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A simple p53 functional assay for screening cell lines, blood, and tumors

Autor: Carlos Martín, J Benhattar, F Charbonnier, J M Flaman, Thierry Frebourg, I M Limacher, P Chappuis, V Moreau, Bron L, A P Sappino

Mutations in the p53 gene are implicated in the pathogenesis of half of all human tumors. We have developed a simple functional assay for p53 mutation in which human p53 expressed in Saccharomyces cerevisiae activates transcription of the ADE2 gene.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0584902ab0aac7eab8536a52d7515ca8
https://europepmc.org/articles/PMC42082/