Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Bromperidol"'
Publikováno v:
Current Pharmaceutical Analysis. 7:235-239
Publikováno v:
Journal of Psychopharmacology. 27:396-400
Second-generation antipsychotics, which have become the standard drug therapies for schizophrenia, are known to have a serotonin 5-HT2A receptor blocking effect in addition to a dopamine D2 receptor blocking effect. However, although chlorpromazine (
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 31:2762-2770
The basic metabolites of butyrophenone-type agents are sometimes more neurotoxic than the parent compounds. Recently, we developed a simple high performance liquid chromatographic (HPLC) method coupled with dual ultraviolet detection to determine the
Publikováno v:
Pharmacology & Toxicology. 86:145-148
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 30:2747-2754
The basic metabolites of butyrophenone type agents are sometimes more neurotoxic than the parent compounds. We have developed a high performance liquid chromatographic method with fluorescence detection (HPLC‐FL) to quantify the N‐dealkylated bas
Autor:
Kristof E. Maudens, Hugo Neels, Lisbeth Patteet, Manuel Morrens, Bernard Sabbe, Willy E. Lambert, Christophe P. Stove
Publikováno v:
Drug testing and analysis
DRUG TESTING AND ANALYSIS
DRUG TESTING AND ANALYSIS
Therapeutic drug monitoring of antipsychotics is important in optimizing individual therapy. In psychiatric populations, classical venous blood sampling is experienced as frightening. Interest in alternative techniques, like dried blood spots (DBS),
Publikováno v:
Biological & Pharmaceutical Bulletin = Biological & Pharmaceutical Bulletin. 29(12):2479-2482
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 29:2853-2862
Some basic metabolites of butyrophenone‐type agents are more neurotoxic than the parent compounds. We have developed a high performance liquid chromatography method with dual ultraviolet detection (HPLC‐dual UV method) to quantify simultaneously
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 21:409-412
We have presented pharmacokinetic parameters of bromperidol (BP) in 14 healthy Korean subjects. Additionally, we have investigated the effects of dose and genetic polymorphisms on BP metabolism and on extrapyramidal symptoms (EPS). The Tmax (3.9 ± 0
Autor:
Zeping Xiao, Tsuyoshi Kondo, Mingdao Zhang, Hiroto Hokama, Jijun Wang, Shin Tanaka, Yoshio Hirayasu
Publikováno v:
Psychiatry and Clinical Neurosciences. 59:209-214
P300 amplitude reduction in schizophrenia is, according to previous studies, partially recovered by treatment with neuroleptics. However, whether this medication-induced P300 recovery is associated with duration of untreated psychosis (DUP) remains u