The predicted transmembrane fragment 17 of the human multidrug resistance protein 1 (MRP1) behaves as an interfacial helix in membrane mimics

Autor: Manuel Garrigos, Béatrice de Foresta, Nadège Jamin, Michel Vincent, Jacques Gallay

Publikováno v: Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, 2007, pp.538-552

The human multidrug resistance protein MRP1 (or ABCC1) is one of the most important members of the large ABC transporter family, in terms of both its biological (tissue defense) and pharmacological functions. Many studies have investigated the functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad94ff8d75ba9ab45d84d4251f66c1b
https://doi.org/10.1016/j.bbamem.2006.11.021

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Interaction with membrane mimics of transmembrane fragments 16 and 17 from the human multidrug resistance ABC transporter 1 (hMRP1/ABCC1) and two of their tryptophan variants

Autor: Jacques Gallay, Manuel Garrigos, Michel Vincent, Béatrice de Foresta

Publikováno v: Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (3), pp.401-414. ⟨10.1016/j.bbamem.2009.11.019⟩

The human multidrug resistance-associated protein 1 (hMRP1/ABCC1) belongs to the ATP-binding cassette transporter superfamily. Together with P-glycoprotein (ABCB1) and the breast cancer resistance protein (BCRP/ABCG2), hMRP1 confers resistance to a l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22cfc4bf8673e41ef6338319cada3c4