Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Broekman, M. M. T. J."'
Autor:
Broekman, M. M. T. J.1 broekmanmark@gmail.com, Coenen, M. J. H.2, Wanten, G. J.1, van Marrewijk, C. J.2, Klungel, O. H.3, Verbeek, A. L. M.4, Hooymans, P. M.5, Guchelaar, H.‐J.6, Scheffer, H.2, Derijks, L. J. J.7, Wong, D. R.5, Jong, D. J.1
Publikováno v:
Alimentary Pharmacology & Therapeutics. Nov2017, Vol. 46 Issue 10, p953-963. 11p.
Autor:
Broekman, M M T J, Wong, D R, Wanten, G J A, Roelofs, H M, van Marrewijk, C J, Klungel, O H, Verbeek, A L M, Hooymans, P M, Guchelaar, H-J, Scheffer, H, Derijks, L J J, Coenen, M J H, de Jong, D J
The conversion of azathioprine (AZA) to mercaptopurine (MP) is mediated by glutathione transferase Mu1 (GSTM1), alpha1 (GSTA1) and alpha2 (GSTA2). We designed a case-control study with data from the TOPIC trial to explore the effects of genetic varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______101::18fa247c7726e9689f4ab8a01d7d9b1b
https://dspace.library.uu.nl/handle/1874/375235
https://dspace.library.uu.nl/handle/1874/375235
Autor:
Broekman, M M T J, Coenen, Marieke J H, Wanten, Geert J A, van Marrewijk, C. J., Klungel, O. H., Verbeek, A. L.M., Hooymans, Piet M, Guchelaar, H.J., Scheffer, H., Derijks, Luc J J, Wong, Dennis R, de Jong, D. J.
Background: Leucopenia is a common side effect in patients treated with thiopurines. Variants in the thiopurine S-methyltransferase (TPMT) gene are the best-known risk factor, but only explain up to 25% of leucopenia cases. Aim: To identify the clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______101::974784a33fba1aed5a9c2ae2f36dec56
https://dspace.library.uu.nl/handle/1874/359452
https://dspace.library.uu.nl/handle/1874/359452
Akademický článek
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Autor:
Lamers, M. H., Broekman, M. M. T. J., Boucher, C. A., Brouwer, J. T., Burger, D. M., Bart van Hoek, Hoepelman, A. I. M., Knegt, R. J., Reesink, H. W., Drenth, J. P. H.
Publikováno v:
Netherlands Journal of Medicine, 71, 7, pp. 377-85
Scopus-Elsevier
Netherlands Journal of Medicine, 71, 377-85
Scopus-Elsevier
Netherlands Journal of Medicine, 71, 377-85
Item does not contain fulltext In this new Dutch guideline for hepatitis C virus infection we provide recommendations for the management of hepatitis C infection. Until 2012 the standard for treatment consisted of pegylated interferon alpha (peg-IFNa
Publikováno v:
Alimentary Pharmacology & Therapeutics. Jan2018, Vol. 47 Issue 1, p130-131. 2p.