Interfering with UDP-GlcNAc Metabolism and Heparan Sulfate Expression Using a Sugar Analogue Reduces Angiogenesis

Autor: Wijk, X.M.R. van, Thijssen, V.L., Lawrence, R., Broek, S.A. van den, Dona, M., Naidu, N., Oosterhof, A., Westerlo, E.M.A. van de, Kusters, L.J., Khaled, Y., Jokela, T.A., Nowak-Sliwinska, P., Kremer, H., Stringer, S.E., Griffioen, A.W., Wijk, E. van, Delft, F.L. van, Kuppevelt, T.H. van

Publikováno v: Acs Chemical Biology, 8, 10, pp. 2331-2338
Acs Chemical Biology, 8, 2331-8
van Wijk, X M, Thijssen, V L, Lawrence, R, van den Broek, S A, Dona, M, Naidu, N, Oosterhof, A, van de Westerlo, E M, Kusters, L J, Khaled, Y, Jokela, T A, Nowak-Sliwinska, P, Kremer, H, Stringer, S E, Griffioen, A W, van Wijk, E, van Delft, F L & van Kuppevelt, T H 2013, ' Interfering with UDP-GlcNAc Metabolism and Heparan Sulfate Expression Using a Sugar Analogue Reduces Angiogenesis ', Acs chemical biology, vol. 8, no. 10, pp. 2331-2338 . https://doi.org/10.1021/cb40043321
Acs chemical biology, 8(10), 2331-2338. American Chemical Society
Acs Chemical Biology, 8, 2331-2338
Acs Chemical Biology, 8, 10, pp. 2331-8

Item does not contain fulltext Heparan sulfate (HS), a long linear polysaccharide, is implicated in various steps of tumorigenesis, including angiogenesis. We successfully interfered with HS biosynthesis using a peracetylated 4-deoxy analogue of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2c399838368cb5943855fe80a20ac4d2
https://hdl.handle.net/2066/123211