Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure.

Autor: Broeders JJ; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands. Electronic address: jessica.broeders@ctgb.nl., Parmentier C; Kaly-Cell, 20A Rue du Général Leclerc, Plobsheim, France., Truisi GL; Non-Clinical Safety, Merck Serono, Merck KGaA, Darmstadt, Germany; Institut für Angewandte Biowissenschaften, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Jossé R; Institut National de la Santé et de la Recherche Médicale U991, Université de Rennes 1, Rennes, France., Alexandre E; Kaly-Cell, 20A Rue du Général Leclerc, Plobsheim, France., Savary CC; Institut National de la Santé et de la Recherche Médicale U991, Université de Rennes 1, Rennes, France., Hewitt PG; Non-Clinical Safety, Merck Serono, Merck KGaA, Darmstadt, Germany., Mueller SO; Non-Clinical Safety, Merck Serono, Merck KGaA, Darmstadt, Germany; Institut für Angewandte Biowissenschaften, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Guillouzo A; Institut National de la Santé et de la Recherche Médicale U991, Université de Rennes 1, Rennes, France., Richert L; Kaly-Cell, 20A Rue du Général Leclerc, Plobsheim, France., van Eijkeren JC; National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Hermens JL; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands., Blaauboer BJ; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2015 Dec 25; Vol. 30 (1 Pt A), pp. 52-61. Date of Electronic Publication: 2014 Nov 04.

Transport of chlorpromazine in the Caco-2 cell permeability assay: a kinetic study.

Autor: Broeders JJ; Institute for Risk Assessment Sciences (IRAS), Utrecht University, P.O. Box 80.177, NL-3508 TD Utrecht, The Netherlands. j.j.w.broeders@uu.nl, van Eijkeren JC, Blaauboer BJ, Hermens JL

Publikováno v: Chemical research in toxicology [Chem Res Toxicol] 2012 Jul 16; Vol. 25 (7), pp. 1442-51. Date of Electronic Publication: 2012 Jun 25.

Novel SPME fibers based on a plastic support for determination of plasma protein binding of thiosemicarbazone metal chelators: a case example of DpC, an anti-cancer drug that entered clinical trials.

Autor: Reimerová, Petra¹ (AUTHOR), Stariat, Ján¹ (AUTHOR), Bavlovič Piskáčková, Hana¹ (AUTHOR), Jansová, Hana¹ (AUTHOR), Roh, Jaroslav¹ (AUTHOR), Kalinowski, Danuta S.² (AUTHOR), Macháček, Miloslav¹ (AUTHOR), Šimůnek, Tomáš¹ (AUTHOR), Richardson, Des R.² (AUTHOR) d.richardson@med.usyd.edu.au, Štěrbová-Kovaříková, Petra¹ (AUTHOR) petra.kovarikova@faf.cuni.cz

Publikováno v: Analytical & Bioanalytical Chemistry. Apr2019, Vol. 411 Issue 11, p2383-2394. 12p.

Oxidative-stress and long-term hepatotoxicity: comparative study in Upcyte human hepatocytes and hepaRG cells.

Autor: Donato, M. Teresa, Jiménez, Nuria, Pelechá, María, Tolosa, Laia

Publikováno v: Archives of Toxicology; Apr2022, Vol. 96 Issue 4, p1021-1037, 17p

Permeation characteristics of hypericin across Caco‐2 monolayers in the presence of single flavonoids, defined flavonoid mixtures or Hypericum extract matrix.

Autor: Verjee, Sheela, Butterweck, Veronika, Kelber, Olaf, Kolb, Christiane, Abdel‐Aziz, Heba

Publikováno v: Journal of Pharmacy & Pharmacology; Jan2019, Vol. 71 Issue 1, p58-69, 12p