Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Broder Fredrich"'
Autor:
Jörn F. Ziegler, Chotima Böttcher, Marilena Letizia, Cansu Yerinde, Hao Wu, Inka Freise, Yasmina Rodriguez-Sillke, Ani K. Stoyanova, Martin E. Kreis, Patrick Asbach, Desiree Kunkel, Josef Priller, Ioannis Anagnostopoulos, Anja A. Kühl, Konstanze Miehle, Michael Stumvoll, Florian Tran, Broder Fredrich, Michael Forster, Andre Franke, Christian Bojarski, Rainer Glauben, Britt-Sabina Löscher, Britta Siegmund, Carl Weidinger
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The adipokine leptin modulates intestinal inflammation in mice. Here the authors describe a patient with inflammatory bowel disease and lipodystrophy, providing evidence that leptin aggravates intestinal inflammation with proinflammatory effects on l
Externí odkaz:
https://doaj.org/article/930d669ed7b944499b66502ad66aa5e6
Autor:
Broder Fredrich, Marcus Schmöhl, Olaf Junge, Sven Gundlach, David Ellinghaus, Arne Pfeufer, Thomas Bettecken, Roman Siddiqui, Andre Franke, Thomas F Wienker, Marc P Hoeppner, Michael Krawczak
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215618 (2019)
Massively parallel DNA sequencing of clinical samples holds great promise for the gene-based diagnosis of human inherited diseases because it allows rapid detection of putatively causative mutations at genome-wide level. Without additional evidence c
Externí odkaz:
https://doaj.org/article/1c9f50136d8a459098b9a522535bc363
Autor:
Rainer Glauben, Broder Fredrich, Anja A. Kühl, Josef Priller, Désirée Kunkel, Ioannis Anagnostopoulos, Andre Franke, Marilena Letizia, Inka Freise, Carl Weidinger, Florian Tran, Chotima Böttcher, Jörn F. Ziegler, Britt-Sabina Löscher, Patrick Asbach, Konstanze Miehle, Ani K. Stoyanova, Hao Wu, Christian Bojarski, Britta Siegmund, Martin E. Kreis, Michael Stumvoll, Cansu Yerinde, Yasmina Rodriguez-Sillke, Michael Forster
Publikováno v:
Nature Communications
Nature Communications 10(1), 5629 (2019). doi:10.1038/s41467-019-13559-7
Ziegler, J F, Böttcher, C, Letizia, M, Yerinde, C, Wu, H, Freise, I, Rodriguez-sillke, Y, Stoyanova, A K, Kreis, M E, Asbach, P, Kunkel, D, Priller, J, Anagnostopoulos, I, Kühl, A A, Miehle, K, Stumvoll, M, Tran, F, Fredrich, B, Forster, M, Franke, A, Bojarski, C, Glauben, R, Löscher, B, Siegmund, B & Weidinger, C 2019, ' Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease ', Nature Communications, vol. 10, no. 1 . https://doi.org/10.1038/s41467-019-13559-7
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications 10(1), 5629 (2019). doi:10.1038/s41467-019-13559-7
Ziegler, J F, Böttcher, C, Letizia, M, Yerinde, C, Wu, H, Freise, I, Rodriguez-sillke, Y, Stoyanova, A K, Kreis, M E, Asbach, P, Kunkel, D, Priller, J, Anagnostopoulos, I, Kühl, A A, Miehle, K, Stumvoll, M, Tran, F, Fredrich, B, Forster, M, Franke, A, Bojarski, C, Glauben, R, Löscher, B, Siegmund, B & Weidinger, C 2019, ' Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease ', Nature Communications, vol. 10, no. 1 . https://doi.org/10.1038/s41467-019-13559-7
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Leptin has been shown to modulate intestinal inflammation in mice. However, clinical evidence regarding its immune-stimulatory potential in human Crohn’s disease remains sparse. We here describe a patient with the unique combination of acquired gen
Autor:
Michael Krawczak, Broder Fredrich, Arne Pfeufer, Marc P. Hoeppner, Thomas Bettecken, Roman A. Siddiqui, Andre Franke, Thomas F. Wienker, David Ellinghaus, Marcus Schmöhl, Olaf Junge, Sven Gundlach
Publikováno v:
PLoS ONE
PLoS One
PLoS ONE, Vol 14, Iss 4, p e0215618 (2019)
PLoS One
PLoS ONE, Vol 14, Iss 4, p e0215618 (2019)
Massively parallel DNA sequencing of clinical samples holds great promise for the gene-based diagnosis of human inherited diseases because it allows rapid detection of putatively causative mutations at genome-wide level. Without additional evidence c
Publikováno v:
BMC Genetics
Recent advances in the development of sequencing technologies provide researchers with unprecedented possibilities for genetic analyses. In this review, we will discuss the history of genetic studies and the progress driven by next-generation sequenc