Zobrazeno 1 - 10
of 16 251
pro vyhledávání: '"Broad-spectrum"'
Autor:
Jinchao Zhang, Qian Zhang, Hang Zou, Jialei Yu, Wei Cao, Shifu Wu, Shuai Qin, Qiang Zhao, Erez Gilad
Publikováno v:
Nuclear Engineering and Technology, Vol 56, Iss 10, Pp 4335-4354 (2024)
Some core designs integrate high-enriched fuel and moderator materials to enhance neutron utilization. This combination results in a broad spectrum within the system, posing challenges in resonance calculation. This paper introduces a general framewo
Externí odkaz:
https://doaj.org/article/1001fabcaaa344c0a5212e99c95f9960
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract In this study, pure V6O13 and nickel ion-doped V6O13 powders were synthesized by a simple hydrothermal-calcination method, and their broad-spectrum antimicrobial properties and mechanisms were investigated. The crystal structure, morphology,
Externí odkaz:
https://doaj.org/article/6ca3b54d62d04268aa18af8e0a10a8ab
Publikováno v:
Natural Products and Bioprospecting, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract Iminosugars, a class of polyhydroxylated cyclic alkaloids with intriguing properties, hold promising therapeutic potentials against a broad spectrum of enveloped viruses, including DENV, HCV, HIV, and influenza viruses. Mechanistically, imin
Externí odkaz:
https://doaj.org/article/7bdfcbfbbe6a45fea3dc0a40949e4908
Publikováno v:
BioMed, Vol 4, Iss 3, Pp 318-337 (2024)
Overuse or misuse of broad-spectrum antibiotics increases the risk of the emergence of antibiotic-resistant bacteria, which increases the possibility of antimicrobial-resistant (AMR) bacterial infections, and subsequently raises healthcare costs. The
Externí odkaz:
https://doaj.org/article/02fec70b5d2e49b98808793973fd7194
Autor:
Chris Chun-Yiu Chan, Qian Guo, Jasper Fuk-Woo Chan, Kaiming Tang, Jian-Piao Cai, Kenn Ka-Heng Chik, Yixin Huang, Mei Dai, Bo Qin, Chon Phin Ong, Allen Wing-Ho Chu, Wan-Mui Chan, Jonathan Daniel Ip, Lei Wen, Jessica Oi-Ling Tsang, Tong-Yun Wang, Yubin Xie, Zhenzhi Qin, Jianli Cao, Zi-Wei Ye, Hin Chu, Kelvin Kai-Wang To, Xing-Yi Ge, Tao Ni, Dong-Yan Jin, Sheng Cui, Kwok-Yung Yuen, Shuofeng Yuan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4028-4044 (2024)
There are only eight approved small molecule antiviral drugs for treating COVID-19. Among them, four are nucleotide analogues (remdesivir, JT001, molnupiravir, and azvudine), while the other four are protease inhibitors (nirmatrelvir, ensitrelvir, le
Externí odkaz:
https://doaj.org/article/e580066405f243c6820a3a4400b16bcf
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4189-4192 (2024)
Externí odkaz:
https://doaj.org/article/12464dbf511143de968887e923a534db
Autor:
Wenjie Zuo, Guobin Yin, Luyao Zhang, Weijiao Zhang, Ruirui Xu, Yang Wang, Jianghua Li, Zhen Kang
Publikováno v:
Synthetic and Systems Biotechnology, Vol 10, Iss 1, Pp 49-57 (2025)
As a fundamental tool in synthetic biology, promoters are pivotal in regulating gene expression, enabling precise genetic control and spurring innovation across diverse biotechnological applications. However, most advances in engineered genetic syste
Externí odkaz:
https://doaj.org/article/10493838cf304e13bdc7528d7aebf780
Autor:
Arunmozhiarasi Armugam, Diane S.W. Lim, Siti Nurhanna Riduan, Shook Pui Chan, Jerome Asugan, Yugen Zhang
Publikováno v:
Green Chemical Engineering, Vol 5, Iss 4, Pp 473-482 (2024)
Antimicrobial materials are a crucial component in eradicating and managing the spread of infectious diseases. They are expected to act on a broad-spectrum of microbes, including emerging pathogens which could cause the next Disease X. Herein, we rea
Externí odkaz:
https://doaj.org/article/6743ddd8fdb445dcaa9e94bada2471b4
Autor:
Kh. A. Abduvosidov, S. M. Chudnykh, V. S. Egorov, A. Yu. Filimonov, I. A. Korolyova, A. S. Kamrukov, V. V. Bagrov, A. V. Kondrat’ev
Publikováno v:
Biomedical Photonics, Vol 13, Iss 2, Pp 26-33 (2024)
The study aimed to investigate the bactericidal eŠcacy of high-intensity pulsed broadband irradiation in the treatment of infected wounds. An experimental study was conducted on 90 mature male Wistar rats. An infected wound model was created by cont
Externí odkaz:
https://doaj.org/article/47632de569b742769733a1f598563e7b