EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis.

Autor: Kuo KH; Division of Medical Oncology and Hematology, University Health Network, Toronto, ON, Canada., Khan S; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada., Rand ML; Division of Hematology, Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada., Mian HS; Department of Medicine, University of Toronto, Toronto, ON, Canada., Brnjac E; Department of Clinical Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada., Sandercock LE; Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada., Akula I; Program in Molecular Structure and Function, The Hospital for Sick Children Research Institute, Toronto, ON, Canada., Julien JP; Program in Molecular Structure and Function, The Hospital for Sick Children Research Institute, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.; Department of Immunology, University of Toronto, Toronto, ON, Canada., Pai EF; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Campbell Family Cancer Research Institute, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Chesney AE; Department of Clinical Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

Publikováno v: PloS one [PLoS One] 2016 Mar 02; Vol. 11 (3), pp. e0149830. Date of Electronic Publication: 2016 Mar 02 (Print Publication: 2016).

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