Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Brizaida, Oliva"'
Cancer is a disease with high incidence. Other therapies as surgery and radiotherapy is also used in the treatment of this disease. However, the effect adverse and the metastasis limited the use of these therapies. Target anticancer Targeted cancer t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45a5408536ba857fca597bd8c7e1920b
https://doi.org/10.22541/au.167335893.33287810/v1
https://doi.org/10.22541/au.167335893.33287810/v1
Autor:
Teresa Núñez de Villavicencio-Díaz, Yassel Ramos Gómez, Brizaida Oliva Argüelles, Julio R. Fernández Masso, Arielis Rodríguez-Ulloa, Yiliam Cruz García, Osmany Guirola-Cruz, Yasset Perez-Riverol, Luis Javier González, Inés Tiscornia, Sabina Victoria, Mariela Bollati-Fogolín, Vladimir Besada Pérez, Maribel Guerra Vallespi
Publikováno v:
Data in Brief, Vol 4, Iss C, Pp 468-473 (2015)
CIGB-552 is a second generation antitumor peptide that displays potent cytotoxicity in lung and colon cancer cells. The nuclear subproteome of HT-29 colon adenocarcinoma cells treated with CIGB-552 peptide was identified and analyzed [1]. This data a
Externí odkaz:
https://doaj.org/article/39fdbd6dad7040039e6ea3301f8e2744
Publikováno v:
Br J Pharmacol
Peptide‐based cancer therapy has been of great interest due to the unique advantages of peptides, such as their low MW, the ability to specifically target tumour cells, easily available and low toxicity in normal tissues. Therefore, identifying and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88dae327633af627c705683b42671fe9
https://doi.org/10.1111/bph.15132
https://doi.org/10.1111/bph.15132
Autor:
Yolanda Gomez Rodriguez, Brizaida Oliva Arguelles, Mario Riera Romo, Jorge Fernandez-De-Cossio, Hilda Elisa Garay Perez, Julio Raul Fernandez Masso, Maribel Guerra Vallespi
Non-small cell lung cancer constitutes one the most frequent and lethal forms of the disease. The antitumor peptide CIGB-552 is a new targeted anticancer therapy which molecular mechanism is associated with the inhibition of the transcription factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29487235fa68d7a51b88a88ef6f0726e
https://doi.org/10.21203/rs.3.rs-620068/v1
https://doi.org/10.21203/rs.3.rs-620068/v1
Autor:
Maribel G, Vallespi, Braulio, Mestre, Maria A, Marrero, Rolando, Uranga, Diana, Rey, Martha, Lugiollo, Mircea, Betancourt, Kirenia, Silva, Danay, Corrales, Yanet, Lamadrid, Yamilka, Rodriguez, Anaelys, Maceo, Pedro P, Chaviano, Gilda, Lemos, Ania, Cabrales, Freya M, Freyre, Hector, Santana, Hilda E, Garay, Brizaida, Oliva, Julio R, Fernandez
Publikováno v:
International journal of cancerREFERENCES. 149(6)
CIGB-552 is a synthetic peptide that interacts with COMMD1 and upregulates its protein levels. The objectives of this phase I study were safety, pharmacokinetic profile, evaluation of the lymphocytes CD4+ and CD8+ and preliminary activity in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d3909af6a241c4044657bc43099172e
https://pubmed.ncbi.nlm.nih.gov/34019700
https://pubmed.ncbi.nlm.nih.gov/34019700
Autor:
Reynold Morales, Carolina Tafalla, Brizaida Oliva, Aymé Oliva, Carolina Aquilino, Tirso Pons, Mario Pablo Estrada, Juana María Lugo
Publikováno v:
Repositorio de Resultados de Investigación del INIA
INIA: Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a regulatory neuropeptide that belongs to the secretin/glucagon superfamily, of which some members have shown antimicrobial activities. Contrasting to mammals, published studies on the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d46ccb5be9d3c2f6592f785bc42568ce
http://hdl.handle.net/20.500.12792/874
http://hdl.handle.net/20.500.12792/874
Autor:
Arielis Rodríguez-Ulloa, Osmany Guirola-Cruz, Julio Raúl Fernández Massó, Vladimir Besada Perez, Luis Javier González, Maribel G. Vallespi, Inés Tiscornia, Sabina Victoria, Yassel Ramos Gómez, Teresa Núñez de Villavicencio-Díaz, Mariela Bollati-Fogolín, Brizaida Oliva Arguelles, Yiliam Cruz García, Yasset Perez-Riverol
Publikováno v:
Journal of Proteomics. 126:163-171
The second generation peptide CIGB-552 has a pro-apoptotic effect on H460 non-small cell lung cancer cells and displays a potent cytotoxic effect in HT-29 colon adenocarcinoma cells though its action mechanism is ill defined. Here, we present the fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd97a1e08cfbbf5f9b0a997bb805155
https://doi.org/10.1016/j.jprot.2015.05.024
https://doi.org/10.1016/j.jprot.2015.05.024
Autor:
Osvaldo Reyes, Brizaida Oliva, Iraida Sanchez, Julio Garza, Hilda Garay, Juan C. Rodriguez, Gilmara Pimentel, Osmani Mendoza, Iduna Fichtner, Maria Rivera Markelova, Tais Basaco, Mariela Bollati-Fogolín, Yolanda Gomez, Ania Cabrales-Rico, Carlos F Calderón, Maribel G. Vallespi, Soledad Astrada
Publikováno v:
Journal of Peptide Science. 20:850-859
Accumulation of the COMMD1 protein as a druggable pharmacology event to target cancer cells has not been evaluated so far in cancer animal models. We have previously demonstrated that a second-generation peptide, with cell-penetrating capacity, terme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74439ba739efab18fe2b096127cabac
https://doi.org/10.1002/psc.2676
https://doi.org/10.1002/psc.2676
Autor:
Fernández Massó, Julio R.1, Argüelles, Brizaida Oliva2, Tejeda, Yelaine1, Astrada, Soledad3, Garay, Hilda4, Reyes, Osvaldo4, Delgado-Roche, Livan5, Bollati-Fogolín, Mariela3, Vallespí, Maribel G.2 maribel.guerra@cigb.edu.cu
Publikováno v:
Journal of Amino Acids. 2013, p1-13. 13p.
Autor:
Livan Delgado-Roche, Maribel G. Vallespi, Hilda Garay, Brizaida Oliva Arguelles, Mariela Bollati-Fogolín, Yelaine Tejeda, Julio Raúl Fernández Massó, Osvaldo Reyes, Soledad Astrada
Publikováno v:
Journal of Amino Acids
Journal of Amino Acids, 2013, 2013, pp.251398. ⟨10.1155/2013/251398⟩
Journal of Amino Acids, 2013, 2013, pp.251398. ⟨10.1155/2013/251398⟩
We have demonstrated that the peptide L-2 designed from an alanine scanning of the Limulus-derived LALF32-51 region is a potential candidate for the anticancer therapy and its cell-penetrating capacity is an associated useful property. By the modific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b5f0553418e284473ae401202ed80a
https://doi.org/10.1155/2013/251398
https://doi.org/10.1155/2013/251398