Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion.

Autor: Brix DM; Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark., Tvingsholm SA; Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark., Hansen MB; Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark., Clemmensen KB; Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark., Ohman T; Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, 00014UH, Helsinki, Finland., Siino V; Institute for Immunotechnology, Medicon Village, Lund University, 223 81, Lund, Sweden., Lambrughi M; Computational Biology Laboratory, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, 2100, Copenhagen, Denmark., Hansen K; Biotech Research and Innovation Center, Copenhagen University, 2200, Copenhagen, Denmark., Puustinen P; Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark., Gromova I; Breast Cancer Biology, Unit of Genome Integrity, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, 2100, Copenhagen, Denmark., James P; Turku Centre for Biotechnology, Åbo Akademi University and University of Turku, 20014, Turku, Finland., Papaleo E; Computational Biology Laboratory, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, 2100, Copenhagen, Denmark., Varjosalo M; Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, 00014UH, Helsinki, Finland., Moreira J; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark., Jäättelä M; Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark. mj@cancer.dk., Kallunki T; Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark. tk@cancer.dk.; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark. tk@cancer.dk.

Publikováno v: Oncogene [Oncogene] 2019 Apr; Vol. 38 (17), pp. 3170-3184. Date of Electronic Publication: 2019 Jan 08.

Screening and identification of small molecule inhibitors of ErbB2-induced invasion.

Autor: Brix DM; Unit of Cell Death and Metabolism, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark., Rafn B; Unit of Cell Death and Metabolism, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark., Bundgaard Clemmensen K; Unit of Cell Death and Metabolism, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark., Andersen SH; Unit of Cell Death and Metabolism, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark., Ambartsumian N; Department of Neuroscience and Pharmacology, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark., Jäättelä M; Unit of Cell Death and Metabolism, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark., Kallunki T; Unit of Cell Death and Metabolism, Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark. Electronic address: tk@cancer.dk.

Publikováno v: Molecular oncology [Mol Oncol] 2014 Dec; Vol. 8 (8), pp. 1703-18. Date of Electronic Publication: 2014 Jul 12.

RNA aptamers as conformational probes and regulatory agents for plasminogen activator inhibitor-1.

Autor: Madsen JB; Danish-Chinese Center for Proteases and Cancer, Aarhus University,10C Gustav Wieds Vej, 8000 Aarhus C, Denmark., Dupont DM, Andersen TB, Nielsen AF, Sang L, Brix DM, Jensen JK, Broos T, Hendrickx ML, Christensen A, Kjems J, Andreasen PA

Publikováno v: Biochemistry [Biochemistry] 2010 May 18; Vol. 49 (19), pp. 4103-15.