Zobrazeno 1 - 10
of 831
pro vyhledávání: '"Brivanlou A"'
Autor:
De Santis, Riccardo, Rice, Eleni, Croft, Gist, Yang, Min, Rosado-Olivieri, Edwin A., Brivanlou, Ali H.
Publikováno v:
In Stem Cell Reports 9 January 2024 19(1):41-53
Publikováno v:
BMC Genomics, Vol 6, Iss 1, p 123 (2005)
Abstract Background Research using the model system Xenopus laevis has provided critical insights into the mechanisms of early vertebrate development and cell biology. Large scale sequencing efforts have provided an increasingly important resource fo
Externí odkaz:
https://doaj.org/article/73a07fb50c8642d2a18b179190a0e40b
Autor:
Tiago L. Laundos, Shu Li, Eric Cheang, Riccardo De Santis, Francesco M. Piccolo, Ali H. Brivanlou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Huntington’s disease (HD) remains an incurable and fatal neurodegenerative disease long after CAG-expansion mutation in the huntingtin gene (HTT) was identified as the cause. The underlying pathological mechanism, whether HTT loss of
Externí odkaz:
https://doaj.org/article/e7ba6f5e50f34c0986aabc6e6020dad0
Autor:
Metzger, Jakob J., Pereda, Carlota, Adhikari, Arjun, Haremaki, Tomomi, Galgoczi, Szilvia, Siggia, Eric D., Brivanlou, Ali H., Etoc, Fred
Publikováno v:
In Cell Reports Methods 19 September 2022 2(9)
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Organizing centers act to pattern surrounding tissues during embryogenesis through the secretion of morphogens. Here the authors model human organizers using light stimulus to geometrically confine SHH expression in differentiating hESCs, generating
Externí odkaz:
https://doaj.org/article/b12f2668d87e40dab43931a94022f9b3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-4 (2021)
In the next 10 years, the continued exploration of human embryology holds promise to revolutionize regenerative and reproductive medicine with important societal consequences. In this Comment we speculate on the evolution of recent advances made and
Externí odkaz:
https://doaj.org/article/cedeb93626a4430aa706ef19120cdd7e
Autor:
Ali H. Brivanlou, Norbert Gleicher
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-4 (2021)
As it fulfills an irresistible need to understand our own origins, research on human development occupies a unique niche in scientific and medical research. In this Comment, we explore the progress in our understanding of human development over the p
Externí odkaz:
https://doaj.org/article/d8485659654241eab1832e08e188d721
Publikováno v:
In Trends in Molecular Medicine August 2021 27(8):731-742
Autor:
Jakob J. Metzger, Carlota Pereda, Arjun Adhikari, Tomomi Haremaki, Szilvia Galgoczi, Eric D. Siggia, Ali H. Brivanlou, Fred Etoc
Publikováno v:
Cell Reports: Methods, Vol 2, Iss 9, Pp 100297- (2022)
Summary: Organoids are carrying the promise of modeling complex disease phenotypes and serving as a powerful basis for unbiased drug screens, potentially offering a more efficient drug-discovery route. However, unsolved technical bottlenecks of repro
Externí odkaz:
https://doaj.org/article/f5db8f46d9f243f3a2072ea7ecf2fe31