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Publikováno v:
Israel Journal of Chemistry. 63
Autor:
Daniel Abegg, Dominic Gregor Hoch, Brendan G. Dwyer, Zhensheng Zhao, Dany Pechalrieu, Anton Shuster, Nan Qiu, Brittney Racioppo, Alexander Adibekian, Chao Wang
Publikováno v:
Angewandte Chemie International Edition. 60:3071-3079
Herein, we report arylazopyrazole ureas and sulfones as a novel class of photoswitchable serine hydrolase inhibitors and present a chemoproteomic platform for rapid discovery of optically controlled serine hydrolase targets in complex proteomes. Spec