Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Brittney Dienes"'
Autor:
Suresh Kumar Balasubramanian, Cassandra M. Hirsch, Michael J. Clemente, Bhumika J. Patel, Mikkael A. Sekeres, Brittney Dienes, Hideki Makishima, Jaroslaw P. Maciejewski, Swapna Thota, Bartlomiej P Przychodzen
Publikováno v:
Oncotarget
Using next generation sequencing we have systematically analyzed a large cohort of 489 patients with bone marrow failure (BMF), including myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), aplastic anemia (AA), and related conditions for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c5526efc7bc918979d16c3c32b73d5
http://europepmc.org/articles/PMC5788620
http://europepmc.org/articles/PMC5788620
Autor:
Satoru Miyano, Kenichi Chiba, Eckhard Jankowsky, Hiroko Tanaka, Yuichi Shiraishi, Bartlomiej P Przychodzen, Daniel J. Lindner, Yvonne Parker, Yang Du, Brittney Dienes, Jaroslaw P. Maciejewski, Wolfgang E. Berdel, James G. Phillips, Hans-Ulrich Klein, Richard A. Padgett, Lucy A. Godley, Kevin Oakley, Chantana Polprasert, Jane E. Churpek, Yogen Saunthararajah, Martin Dugas, Hideki Makishima, Sudipto Mukherjee, Michael J. Clemente, Utz Krug, Carsten Müller-Tidow, Xiaorong Gu, Naoko Hosono, Kenichi Yoshida, Mikkael A. Sekeres, Isabell Schulze, Daniel A. Pollyea, Jarnail Singh, Nhu Nguyen, Caroline Pabst, Seishi Ogawa
Publikováno v:
Cancer Cell. 27:658-670
SummaryMost cases of adult myeloid neoplasms are routinely assumed to be sporadic. Here, we describe an adult familial acute myeloid leukemia (AML) syndrome caused by germline mutations in the DEAD/H-box helicase gene DDX41. DDX41 was also found to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ceaa19decd33a9642a3214196e3d20
https://doi.org/10.1016/j.ccell.2015.03.017
https://doi.org/10.1016/j.ccell.2015.03.017
Autor:
Naoko Hosono, Inés Gómez-Seguí, Torsten Haferlach, Hiroko Tanaka, Yusuke Sato, Yusuke Shiozawa, Swapna Thota, Teodora Kuzmanovic, Cassandra M. Hirsch, Kenichi Yoshida, Mikkael A. Sekeres, Lee Yung Shih, Claudia Haferlach, Seishi Ogawa, Manja Meggendorfer, Kenichi Chiba, Bartlomie J. Przychodzen, Aiko Sato-Otsubo, Brittney Dienes, Yusuke Okuno, Hiromichi Suzuki, Wolfgang Kern, Masashi Sanada, Tsuyoshi Nakamaki, Kathryn M Guinta, Yogen Saunthararajah, Hideki Makishima, Shigeru Chiba, Thomas LaFramboise, Tetsuichi Yoshizato, Yasunobu Nagata, Yuichi Shiraishi, Jaroslaw P. Maciejewski, Tomas Radivoyevitch, Satoru Miyano, Holleh D Husseinzadeh, Shuichi Miyawaki
Publikováno v:
Nat Genet
To elucidate differential roles of mutations in myelodysplastic syndromes (MDS), we investigated clonal dynamics using whole-exome and/or targeted sequencing of 699 patients, of whom 122 were analyzed longitudinally. Including the results from previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63656a01c7407f19e5f1d21042cdf59b
https://pubmed.ncbi.nlm.nih.gov/27992414
https://pubmed.ncbi.nlm.nih.gov/27992414
Autor:
Vicente Vicente, Ana María Hurtado, Bartlomiej P Przychodzen, F de Arriba, Tzu Hua Chen-Liang, María-Dolores García-Malo, Jaroslaw P. Maciejewski, Brittney Dienes, Francisco José Ortuño, C. Hamedi, Andres Jerez, Ana Isabel Antón, Raúl Teruel-Montoya, Julia Muñoz-Ballester
Publikováno v:
Blood Cancer Journal
An increasing numbers of patients are being diagnosed with asymptomatic early-stage chronic lymphocytic leukemia (CLL), with no treatment indication at baseline. We applied a high-throughput deep-targeted analysis, especially designed for covering wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ac54265c84b0602dd533354cf2b105
https://pubmed.ncbi.nlm.nih.gov/26314984
https://pubmed.ncbi.nlm.nih.gov/26314984
Autor:
Manja Meggendorfer, Yasunobu Nagata, Seishi Ogawa, Inés Gómez-Seguí, Kenichi Chiba, Tetsuichi Yoshizato, Yusuke Sato, Hiromichi Suzuki, Yusuke Shiozawa, Swapna Thota, Shuichi Miyawaki, Satoru Miyano, Bartlomiej P Przychodzen, Holleh D Husseinzadeh, Masashi Sanada, Kenichi Yoshida, Cassandra M. Hirsch, Tsuyoshi Nakamaki, Kathryn M Guinta, Yogen Saunthararajah, Hiroko Tanaka, Aiko Sato-Otsubo, Claudia Haferlach, Lee-Yung Shih, Teodora Kuzmanovic, Wolfgang Kern, Yusuke Okuno, Tomas Radivoyevitch, Shigeru Chiba, Thomas LaFramboise, Yuichi Shiraishi, Jaroslaw P. Maciejewski, Torsten Haferlach, Brittney Dienes, Hideki Makishima, Naoko Hosono, Mikkael A. Sekeres
Publikováno v:
Blood. 128:4287-4287
Myelodysplastic syndromes (MDS) are a heterogeneous group of chronic myeloid neoplasms, in which disease progression is quite common, eventually terminating in secondary acute myeloid leukemia (sAML). To elucidate differential roles of mutations in M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e34d304f6cefc94d78a25685344eaad7
https://doi.org/10.1182/blood.v128.22.4287.4287
https://doi.org/10.1182/blood.v128.22.4287.4287
Autor:
Matt Kalaycio, Hetty E. Carraway, Sudipto Mukherjee, Jaroslaw P. Maciejewski, Bartlomiej P Przychodzen, Mikkael A. Sekeres, Brittney Dienes, David J. Seastone, Tom Radivoyevitch, Anjali S. Advani, Aziz Nazha, Jennifer S. Carew, Aaron T. Gerds
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 15:S195-S196
230 ASXL1 Mutations in AML: Molecular Biomarker for Secondary AML? Jingmei Hsu, MD/PhD, Anita Kumar, MD/MS, Martin Carroll, MD, Noelle Frey, MD, Nirav Shah, MD, Jianhua Zhao, PhD, Elizabeth Hexner, MD, Alison Loren, MD/PhD, Alexander Perl, MD, David
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddbe7961ab87f2242c9e68251b40bee5
https://doi.org/10.1016/j.clml.2015.04.048
https://doi.org/10.1016/j.clml.2015.04.048
Autor:
Brittney Dienes, Satu Mustjoki, Hanna Rajala, Michael J. Clemente, Holleh D Husseinzadeh, Bartlomiej P Przychodzen, Marcin W. Wlodarski, Manuel G. Afable, Jaroslaw P. Maciejewski, Andres Jerez
Publikováno v:
Blood. 122(25)
New massively parallel sequencing technology enables, through deep sequencing of rearranged T-cell receptor (TCR) Vβ complementarity-determining region 3 (CDR3) regions, a previously inaccessible level of TCR repertoire analysis. The CDR3 repertoire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e00943efb6bf066890c2fba59b0dc3
https://pubmed.ncbi.nlm.nih.gov/24149287
https://pubmed.ncbi.nlm.nih.gov/24149287
Autor:
Masashi Sanada, Tsuyoshi Nakamaki, Kathryn M Guinta, Yogen Saunthararajah, Lee-Yung Shih, Michael J. Clemente, Kenichi Chiba, Bartlomiej P Przychodzen, Shigeru Chiba, Kenichi Yoshida, Brittney Dienes, Tetsuichi Yoshizato, Hideki Makishima, Hiromichi Suzuki, Satoru Miyano, Holleh D Husseinzadeh, Seishi Ogawa, Thomas LaFramboise, Yusuke Sato, Yusuke Shiozawa, Naoko Hosono, Swapna Thota, Matthew Ruffalo, Hiroko Tanaka, Shuichi Miyawaki, Inés Gómez-Seguí, Aiko Sato-Otsubo, Mikkael A. Sekeres, Yusuke Okuno, Yuichi Shiraishi, Jaroslaw P. Maciejewski, Yasunobu Nagata
Publikováno v:
Blood. 126:709-709
MDS and related disorders, including MDS/MPN and sAML that evolved from these conditions constitute disease continuum characterized by a wide spectrum of molecular lesions which often overlap. Here, we defined general mutational spectrum and clonal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a24dd161c94a1545318dbc705f021399
https://doi.org/10.1182/blood.v126.23.709.709
https://doi.org/10.1182/blood.v126.23.709.709
Autor:
Kenichi Yoshida, Carsten Müller-Tidow, Seishi Ogawa, Hiroko Tanaka, Satoru Miyano, Yuichi Shiraishi, Kenichi Chiba, Brittney Dienes, Jaroslaw P. Maciejewski, Wolfgang E. Berdel, Chantana Polprasert, Hideki Makishima, Jarnail Singh, Bartlomiej P Przychodzen, Martin Dugas, Hans-Ulrich Klein, Xiaorong Gu, Naoko Hosono, Richard A. Padgett, Mikkael A. Sekeres, Michael J. Clemente, Utz Krug, Sudipto Mukherjee, Eckhard Jankowsky, Isabell Schulze
Publikováno v:
Blood. 124:125-125
Familial MDS is rare and usually occurs at a young age. Distinguishing familial from sporadic disease at the typical late age of disease onset is difficult. While investigating the genetic background in familial AML cases, we identified 5 families ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b32a2c80a1e37a0b059f25f3b81da369
https://doi.org/10.1182/blood.v124.21.125.125
https://doi.org/10.1182/blood.v124.21.125.125
Autor:
Hetty E. Carraway, Kristin Colaluca, Aziz Nazha, Jennifer S. Carew, Bartlomiej P Przychodzen, Gina Rupp, Mikkael A. Sekeres, Brittney Dienes, Anjali S. Advani, Aaron T. Gerds, Sudipto Mukherjee, Jaroslaw P. Maciejewski, Matt Kalaycio, David J. Seastone, Sean Hobson, Tomas Radivoyevitch
Publikováno v:
Blood. 124:3274-3274
Background: African-American (AA) patients (pts) have a younger age at diagnosis and worse outcomes compared to whites (WTs) across many cancers, including acute myeloid and lymphoblastic leukemias. This difference may be related to disease biology r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f246ee39cdc1698e0bceb3e86204e1dc
https://doi.org/10.1182/blood.v124.21.3274.3274
https://doi.org/10.1182/blood.v124.21.3274.3274