Rational immunosilencing of a promiscuous T-cell epitope in the capsid of an adeno-associated virus.

Autor: Bing SJ; Division of Gene Therapy 2, Office of Gene Therapy, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Seirup M; Promega Corporation, Madison, WI, USA., Hoang TT; Promega Corporation, Madison, WI, USA., Najera SS; Division of Gene Therapy 2, Office of Gene Therapy, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Britten C; Waters | Wyatt Technology, Santa Barbara, CA, USA., Warrington SL; Division of Gene Therapy 2, Office of Gene Therapy, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Chu SL; Division of Gene Therapy 2, Office of Gene Therapy, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA., Mazor R; Division of Gene Therapy 2, Office of Gene Therapy, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA. ronit.mazor@fda.hhs.gov.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2024 Feb; Vol. 8 (2), pp. 193-200. Date of Electronic Publication: 2023 Nov 23.

O1–125 - PH 1 Study of PI3KMTOR Inhibitors PF-04691502 or PF-05212384 + MEK Inhibitor PD-0325901 or Irinotecan in Advanced Cancer

Autor: Britten, C., Wainberg, Z., Tabernero, J., Maqueda, M.A., Leong, S., Sessa, C., Millham, R., Hirohashi, T., Siu, L.L., Brana, I.

Publikováno v: In Annals of Oncology November 2013 24 Supplement 9:ix42-ix42

Improving precision for detecting change in the shape of the cornea in patients with keratoconus

Autor: Brunner, M, Czanner, G, Vinciguerra, R, Romano, V, Ahmad, S, Batterbury, M, Britten, C, Willoughby, CE, Kaye, SB

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Scientific Reports
SCIENTIFIC REPORTS

To investigate a method for precision analysis to discriminate true corneal change from measurement imprecision in keratoconus (KC). Thirty patients with KC and 30 healthy controls were included. Coefficients of repeatability and limits of agreement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bdd8718c7efec6d607d069706a14a6f0
https://hdl.handle.net/11379/571501

Preoperative autologous blood donation for bone marrow harvests: Are we wasting donors' time and blood?

Autor: Mijovic, A.^1,2 aleksandar.mijovic@kingsch.nhs.uk, Britten, C.¹, Regan, F.², Harrison, J.²

Publikováno v: Transfusion Medicine. Feb2006, Vol. 16 Issue 1, p57-62. 6p. 3 Charts, 3 Graphs.

Robustness Assessment of Oncology Dose-Finding Trials Using the Modified Fragility Index.

Autor: Shi, Amy X.¹ (AUTHOR), Zhou, Heng² (AUTHOR) heng.zhou@merck.com, Nie, Lei³ (AUTHOR) lei.nie@fda.hhs.gov, Lin, Lifeng⁴ (AUTHOR) lifenglin@arizona.edu, Li, Hongjian⁵ (AUTHOR) hongjian.li@astrazeneca.com, Chu, Haitao^6,7 (AUTHOR) chux0051@umn.edu

Publikováno v: Cancers. Oct2024, Vol. 16 Issue 20, p3504. 11p.