Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Britte C. Beaudette"'
Autor:
Sandra Zakrzewski, Patrick J. Stiff, Phong T. Le, Britte C. Beaudette-Zlatanova, Katherine L. Knight, Shubin Zhang, Mala Parthasarathy
Publikováno v:
Bone marrow transplantation
We evaluated immune reconstitution in 58 adults who received hematopoietic stem cell transplants from allogeneic siblings (allosib), matched unrelated donors (MUD), or cord blood (CB) at 90-day intervals for one year post-transplant. CB recipients ha
Autor:
Dale L. Greiner, Nancy E. Phillips, Raymond M. Welsh, Evelyn A. Kurt-Jones, John P. Mordes, Thomas B. Thornley, Thomas G. Markees, Leonard D. Shultz, Kapil Bahl, Aldo A. Rossini, Michael A. Brehm, Britte C. Beaudette-Zlatanova
Publikováno v:
The Journal of Immunology. 179:6620-6629
TLR activation of innate immunity prevents the induction of transplantation tolerance and shortens skin allograft survival in mice treated with costimulation blockade. The mechanism by which TLR signaling mediates this effect has not been clear. We n
Autor:
Aldo A. Rossini, Danny Zipris, Jean Leif, HA Drexhage, Dale L. Greiner, Mohammed Javeed I. Ansari, Jan Rozing, T Hunig, Christopher D. Benjamin, Hideo Yagita, Britte C. Beaudette-Zlatanova, Barbara J. Whalen, Henk Groen, Mohamed H. Sayegh, John P. Mordes
Publikováno v:
American Journal of Transplantation, 6(5), 894-902. Wiley-Blackwell Publishing Ltd
American Journal of Transplantation, 6(5), 894-902. Wiley
American Journal of Transplantation, 6(5), 894-902. Wiley
Costimulatory signals regulate T-cell activation. To investigate the role of costimulation in autoimmunity and transplantation, we studied the BB rat model of type 1 diabetes. Diabetes-prone BB (BBDP) rats spontaneously develop disease when 55-120 da
Autor:
Mark J. Shlomchik, Ian R. Rifkin, Ann Marshak-Rothstein, Elizabeth A. Leadbetter, Britte C. Beaudette, Andreas Hohlbaum
Publikováno v:
Nature. 416:603-607
Autoreactive B cells are present in the lymphoid tissues of healthy individuals, but typically remain quiescent. When this homeostasis is perturbed, the formation of self-reactive antibodies can have serious pathological consequences. B cells express
Autor:
Ian R. Rifkin, Padma L. Channavajhala, Heather L.B. Kiefer, Adrienne J. Carmack, Esther Landesman-Bollag, Britte C. Beaudette, Brian Jersky, David J. Salant, Shyr-Te Ju, Ann Marshak-Rothstein, David C. Seldin
Publikováno v:
The Journal of Immunology. 161:5164-5170
MRL-lpr/lpr mice have a Fas receptor mutation that leads to abnormalities of apoptosis, lymphoproliferation, and a lupus-like autoimmune disease associated with the production of autoantibodies. Other than Fas pathway defects, little is known about m
Autor:
Jianzhu Chen, Kathrin Linkemann, Britte C. Beaudette, Ann Marshak-Rothstein, Tara Schmidt, Marianne Boes
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 97(3)
Individuals with systemic lupus erythematosus and rheumatoid arthritis are characterized by the presence of high levels of circulating IgM and IgG autoantibodies. Although IgG autoantibodies often are pathogenic, the role of IgM autoantibodies in aut
Autor:
Katherine L. Knight, Patrick J. Stiff, Britte C. Beaudette-Zlatanova, Phong T. Le, Shubin Zhang
Publikováno v:
Clinical Immunology. 135:S89
Publikováno v:
The Journal of Immunology. 182:141.21-141.21
Successful cord blood (CB) transplantation in adults is hampered by low numbers of hematopoietic stem cells (HSC) and infection due to delayed establishment of immunocompetence. By performing CDR3 spectratype analysis of T and B lymphocytes from CB t
Autor:
Mark J. Shlomchik, Cornelia Kiani, Britte C. Beaudette, Ian R. Rifkin, Marc Monestier, Ann Marshak-Rothstein, Elizabeth A. Leadbetter
Publikováno v:
Europe PubMed Central
The fate of an autoreactive B cell is determined in part by the nature of the interaction of the B cell receptor with its autoantigen. In the lpr model of systemic autoimmunity, as well as in certain human diseases, autoreactive B cells expressing rh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541f4ca2e8402e4b36612dd614bf96ac
http://europepmc.org/abstract/med/10903773
http://europepmc.org/abstract/med/10903773