Výsledky vyhledávání - "Brittany Ricart"

Phase I Study of Entinostat in Combination with Enzalutamide for Treatment of Patients with Metastatic Castration-Resistant Prostate Cancer

Autor: Brittany Ricart, Alejandro Villagra, Yan Ma, Jacob Elkon, Satish Noonepalle, Brooke Burgess, Robert S. Siegel, Christian Zevallos-Delgado, Erica Palmer, Jianqing Lin

Publikováno v: Oncologist

Lessons Learned Entinostat at the selected dose levels in combination with a standard dose of enzalutamide showed a promising safety profile in this small phase I study Background Entinostat inhibits prostate cancer (PCa) growth and suppresses Treg c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b400a1699fa9868a970f1bbebeb2b68
https://pubmed.ncbi.nlm.nih.gov/34427023

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Phase I study of entinostat in combination with enzalutamide for treatment of patients with castration-resistant prostate cancer

Autor: Brooke Burgess, Alejandro Villagra, Yan Ma, Brittany Ricart, Jacob Elkon, Erica Palmer, Robert S. Siegel, Jianqing Lin

Publikováno v: Journal of Clinical Oncology. 39:96-96

96 Background: Entinostat (SNDX-275, MS-275) is an oral histone deacetylase (HDAC) inhibitor with selectivity towards class I and IV HDACs. Entinostat inhibits prostate cancer (PCa) growth and suppresses Treg cell function in vitro and in vivo. The p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e794dcf65d674c65abc5cfc0aad1a5d6
https://doi.org/10.1200/jco.2021.39.6_suppl.96

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