Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Brittany Masatsugu"'
Autor:
Kiev S. Ly, Andrew Richard Hudson, Christine Hoffmaster, James T. Limberis, J. Guy Breitenbucher, Richard Barido, De Michael Chung, Yingzhuo Yan, Gary Anderson, Vincent J. Santora, Dany Gitnick, Dong Lee, Brett C. Bookser, Anne Danks, Robert E. Petroski, Graeme Freestone, Varsha Gupta, Clifford Cabebe, Andrew Morse, Michael R. Kennedy, Kristen Sebring, Zachary W. Yoder, Douglas Zook, Marco Peters, Chih-Kun Chai, Joel Renick, Jim Na, Theresa A. Almos, Shouzhen Xia, Ali Tabatabaei, John Nikpur, Samantha Sevidal, Stephine Chow, Mi Chen, Jillian Basinger, Chris L. Bellows, Lindsay Heger, David Neul, Jenny Wen, Brittany Masatsugu, Nicola J. Broadbent, Alan P. Kaplan, Chi Ching Mak
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(14)
A strategy to conformationally restrain a series of GlyT1 inhibitors identified potent analogs that exhibited slowly interconverting rotational isomers. Further studies to address this concern led to a series of azetidine-based inhibitors. Compound 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912579fcc2f963bd82182bdd275301b0
https://pubmed.ncbi.nlm.nih.gov/32527538
https://pubmed.ncbi.nlm.nih.gov/32527538
Autor:
Tomonori Takeuchi, Jose-Maria Carames, Mohammad Zaki Bin Ibrahim, Brittany Masatsugu, Alice I Ayres, Nicola J. Broadbent, Marco Peters, Marta Corcoles, Dorothy Tse, Elizabeth Begg, Monica Munoz, Andrea Moreno, Theofilos Mazidzoglou, Richard G. M. Morris, Anna Padanyi, Lauren Strickland, Lucas Berend Lumeij
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60439e042f82a238ca9910222a53513f
https://doi.org/10.1111/ejn.14681/v2/response1
https://doi.org/10.1111/ejn.14681/v2/response1
Autor:
David Neul, Andrew Morse, Joel Renick, Brittany Masatsugu, Chi Ching Mak, James T. Limberis, Dany Gitnick, Zachary W. Yoder, Michael R. Kennedy, Kiev S. Ly, Samantha Sevidal, Richard Barido, Robert E. Petroski, Graeme Freestone, Clifford Cabebe, Jillian Basinger, Vincent J. Santora, Christine Hoffmaster, Chris L. Bellows, Yingzhuo Yan, Mi Chen, De Michael Chung, John Nikpur, Kristen Sebring, Jenny Wen, Ali Tabatabaei, Brett C. Bookser, Theresa A. Almos, Andrew Richard Hudson, J. Guy Breitenbucher, Chih-Kun Chai, Dong Lee, Lindsay Crickard, Anne Danks, Varsha Gupta, Marco Peters, Alan P. Kaplan, Jim Na, Nicola J. Broadbent, Stephine Chow, Douglas Zook
Publikováno v:
Journal of Medicinal Chemistry. 61:6018-6033
We report here the identification and optimization of a novel series of potent GlyT1 inhibitors. A ligand design campaign that utilized known GlyT1 inhibitors as starting points led to the identification of a novel series of pyrrolo[3,4- c]pyrazoles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3769bd94e72c5343ca6a4bb3a9739f64
https://doi.org/10.1021/acs.jmedchem.8b00372
https://doi.org/10.1021/acs.jmedchem.8b00372
Autor:
Mohammad Zaki Bin Ibrahim, Marta Corcoles, Andrea Moreno, Nicola J. Broadbent, Richard G. M. Morris, Anna Padanyi, Lauren Strickland, Mónica Muñoz-López, Elizabeth Begg, Lucas Berend Lumeij, Dorothy Tse, Jose-Maria Carames, Alice I Ayres, Brittany Masatsugu, Theofilos Mazidzoglou, Tomonori Takeuchi, Marco Peters
Publikováno v:
Broadbent, N, Lumeij, L, Corcoles-Parada, M, Ayres, A, bin Ibrahim, M Z, Masatsugu, B, Moreno, A, Carames Tejedor, J, Begg, E, Strickland, L, Mazidzoglou, T, Padanyi, A, Munoz, M, Takeuchi, T, Peters, M, Morris, R & Tse, D 2020, ' A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory ', European Journal of Neuroscience . https://doi.org/10.1111/ejn.14681
Broadbent, N, Lumeij, L B, Corcoles, M, Ayres, A I, Bin Ibrahim, M Z, Masatsugu, B, Moreno, A, Carames, J M, Begg, E, Strickland, L, Mazidzoglou, T, Padanyi, A, Munoz-Lopez, M, Takeuchi, T, Peters, M, Morris, R G M & Tse, D 2020, ' A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory ', European Journal of Neuroscience, vol. 51, no. 7, pp. 1539-1558 . https://doi.org/10.1111/ejn.14681
Takeuchi, T 2020, ' A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory ', European Journal of Neuroscience . https://doi.org/10.1111/ejn.14681
Broadbent, N, Lumeij, L B, Corcoles, M, Ayres, A I, Bin Ibrahim, M Z, Masatsugu, B, Moreno, A, Carames, J M, Begg, E, Strickland, L, Mazidzoglou, T, Padanyi, A, Munoz-Lopez, M, Takeuchi, T, Peters, M, Morris, R G M & Tse, D 2020, ' A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory ', European Journal of Neuroscience, vol. 51, no. 7, pp. 1539-1558 . https://doi.org/10.1111/ejn.14681
Takeuchi, T 2020, ' A stable home-base promotes allocentric memory representations of episodic-like everyday spatial memory ', European Journal of Neuroscience . https://doi.org/10.1111/ejn.14681
A key issue in neurobiological studies of episodic-like memory is the geometric frame of reference in which memory traces of experience are stored. Assumptions are sometimes made that specific protocols favour either allocentric (map-like) or egocent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070daa9e756bde0da8d2f7a70e5932f1
https://pubmed.ncbi.nlm.nih.gov/31944427
https://pubmed.ncbi.nlm.nih.gov/31944427