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Secondary mitochondria-derived activator of caspases (SMAC) mimetics are being tested in dozens of clinical trials to treat cancer. These targeted therapies mimic endogenous molecules that promote apoptosis by antagonizing inhibitors of apoptosis (IA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12fff8e79754f793dd2597de660282c6
https://doi.org/10.1101/2021.11.09.466489
https://doi.org/10.1101/2021.11.09.466489
Publikováno v:
Brittany Ligman
Second mitochondria-derived activator of caspase (SMAC) mimetics are small molecule drugs currently in cancer clinical trials. They are thought to act by antagonizing inhibitors of apoptosis (IAPs), which are often overexpressed in malignancies. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0c1be6ded88acc4a40a80c026e2d4a
https://journals.aai.org/jimmunol/article-split/204/1_Supplement/246.13/63353/The-effect-of-SMAC-mimetics-on-human-T-cell
https://journals.aai.org/jimmunol/article-split/204/1_Supplement/246.13/63353/The-effect-of-SMAC-mimetics-on-human-T-cell