Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Brittany L. Allen-Petersen"'
Autor:
Dmytro Grygoryev, Taelor Ekstrom, Elise Manalo, Jason M. Link, Amani Alshaikh, Dove Keith, Brittany L. Allen-Petersen, Brett Sheppard, Terry Morgan, Abdenour Soufi, Rosalie C. Sears, Jungsun Kim
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27221- (2024)
Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly intratumorally heterogeneous disease that includes several subtypes and is highly plastic. Effective gene delivery to all PDAC cells is essential for modulating gene expression and ident
Externí odkaz:
https://doaj.org/article/c2d0ac08375d4ae4ba0faf1e9613a512
Autor:
Vidhi M. Shah, Craig Dorrell, Adel Al-Fatease, Brittany L. Allen-Petersen, Yeonhee Woo, Yuliya Bortnyak, Rohi Gheewala, Brett C. Sheppard, Rosalie C. Sears, Adam WG. Alani
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 713 (2022)
Pancreatic ductal adenocarcinoma (PDAC) presents as an unmet clinical challenge for drug delivery due to its unique hypoxic biology. Vinblastine-N-Oxide (CPD100) is a hypoxia-activated prodrug (HAP) that selectively converts to its parent compound, v
Externí odkaz:
https://doaj.org/article/683dea412c074d39add29de2c831bed1
Autor:
Amy S. Farrell, Meghan Morrison Joly, Brittany L. Allen-Petersen, Patrick J. Worth, Christian Lanciault, David Sauer, Jason Link, Carl Pelz, Laura M. Heiser, Jennifer P. Morton, Nathiya Muthalagu, Megan T. Hoffman, Sara L. Manning, Erica D. Pratt, Nicholas D. Kendsersky, Nkolika Egbukichi, Taylor S. Amery, Mary C. Thoma, Zina P. Jenny, Andrew D. Rhim, Daniel J. Murphy, Owen J. Sansom, Howard C. Crawford, Brett C. Sheppard, Rosalie C. Sears
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Neuroendocrine differentiation of epithelial tumor cells can contribute to cancer cell resistance and survival. Here, the authors show that dysregulated c-Myc promotes neuroendocrine differentiation in pancreatic ductal adenocarcinoma, leading to poo
Externí odkaz:
https://doaj.org/article/dc766b609bac46f8805ef957d3259818
Autor:
Mara H. Sherman, Jurre J. Kamphorst, Rosalie C. Sears, Jim C. Norman, Jennifer P. Morton, Craig Dorrell, Colin Nixon, Ronald M. Evans, Rosa F. Hwang, David Novo, Michelle Schug, Esmee Vringer, Nicholas D. Kendsersky, Jason Link, Brittany L. Allen-Petersen, Sergey Tumanov, Sohinee Bhattacharyya, Mark Berry, Jacqueline Tait-Mulder, Chet Oon, Vinay Bulusu, Francesca R. Auciello
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b073e59a30c870401a24ddf83ddbc39
https://doi.org/10.1158/2159-8290.22532899
https://doi.org/10.1158/2159-8290.22532899
Autor:
Mara H. Sherman, Jurre J. Kamphorst, Rosalie C. Sears, Jim C. Norman, Jennifer P. Morton, Craig Dorrell, Colin Nixon, Ronald M. Evans, Rosa F. Hwang, David Novo, Michelle Schug, Esmee Vringer, Nicholas D. Kendsersky, Jason Link, Brittany L. Allen-Petersen, Sergey Tumanov, Sohinee Bhattacharyya, Mark Berry, Jacqueline Tait-Mulder, Chet Oon, Vinay Bulusu, Francesca R. Auciello
Figure S1-S5 with legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d112b8f8b610cdfc755fd1de6603a7d
https://doi.org/10.1158/2159-8290.22532902.v1
https://doi.org/10.1158/2159-8290.22532902.v1
Autor:
Mara H. Sherman, Jurre J. Kamphorst, Rosalie C. Sears, Jim C. Norman, Jennifer P. Morton, Craig Dorrell, Colin Nixon, Ronald M. Evans, Rosa F. Hwang, David Novo, Michelle Schug, Esmee Vringer, Nicholas D. Kendsersky, Jason Link, Brittany L. Allen-Petersen, Sergey Tumanov, Sohinee Bhattacharyya, Mark Berry, Jacqueline Tait-Mulder, Chet Oon, Vinay Bulusu, Francesca R. Auciello
Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f781a3ef8422e1dbaf631f79ca4982
https://doi.org/10.1158/2159-8290.22532896
https://doi.org/10.1158/2159-8290.22532896
Autor:
Rosalie C. Sears, Goutham Narla, Michael Ohlmeyer, Dale J. Christensen, Brett Sheppard, Charles D. Lopez, Owen J. Sansom, Jennifer P. Morton, Katherine R. Pelz, Mary C. Thoma, Zina P. Jenny, Zhiping Wang, Zipei Feng, Tyler Risom, Brittany L. Allen-Petersen
Results of Kinase Inhibitor Screen including compound names, IC50s, and fold change compared to vehicle.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298272d763f56207a4f8b0acbfb53814
https://doi.org/10.1158/0008-5472.22421378.v1
https://doi.org/10.1158/0008-5472.22421378.v1
Autor:
Rosalie C. Sears, Goutham Narla, Michael Ohlmeyer, Dale J. Christensen, Brett Sheppard, Charles D. Lopez, Owen J. Sansom, Jennifer P. Morton, Katherine R. Pelz, Mary C. Thoma, Zina P. Jenny, Zhiping Wang, Zipei Feng, Tyler Risom, Brittany L. Allen-Petersen
Viability assays, Soft agar, Immunoprecipitation, Kinase inhibitor screen, and Patient outcome data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446537c73f9efea03dca3e1abae52f85
https://doi.org/10.1158/0008-5472.22421369.v1
https://doi.org/10.1158/0008-5472.22421369.v1
Autor:
Rosalie C. Sears, Goutham Narla, Michael Ohlmeyer, Dale J. Christensen, Brett Sheppard, Charles D. Lopez, Owen J. Sansom, Jennifer P. Morton, Katherine R. Pelz, Mary C. Thoma, Zina P. Jenny, Zhiping Wang, Zipei Feng, Tyler Risom, Brittany L. Allen-Petersen
Results of the Phosphokinase Array with phosphorylation sites, fold change relative to vehicle, and Kmeans clustering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0088b85088bf7a980881e3de059f98
https://doi.org/10.1158/0008-5472.22421375.v1
https://doi.org/10.1158/0008-5472.22421375.v1
Autor:
Rosalie C. Sears, Goutham Narla, Michael Ohlmeyer, Dale J. Christensen, Brett Sheppard, Charles D. Lopez, Owen J. Sansom, Jennifer P. Morton, Katherine R. Pelz, Mary C. Thoma, Zina P. Jenny, Zhiping Wang, Zipei Feng, Tyler Risom, Brittany L. Allen-Petersen
Supplemental Figures S1-S9. S1: Kinase inhibitor screen and response of OP449 and INK128. S2: CI values for DT1154 combined with INK128 and viability curves. S3: Kmeans clusters and signaling in response to PP2A activators and INK128. S4: Oncoprint a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6733ae9b9a68b8a98c97af49a832aaad
https://doi.org/10.1158/0008-5472.22421372
https://doi.org/10.1158/0008-5472.22421372