Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Brittany J. Bisnett"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
The coat protein complex II (COPII) mediates forward trafficking of protein and lipid cargoes from the endoplasmic reticulum. COPII is an ancient and essential pathway in all eukaryotes and COPII dysfunction underlies a range of human diseases. Despi
Externí odkaz:
https://doaj.org/article/c7ebcdf9ce754b63bb922ba92c4a4aa7
Autor:
Nathan J. Cox, Peter M. Luo, Timothy J. Smith, Brittany J. Bisnett, Erik J. Soderblom, Michael Boyce
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
O-linked β-N-acetylglucosamine (O-GlcNAc) is an abundant and essential intracellular form of protein glycosylation in animals and plants. In humans, dysregulation of O-GlcNAcylation occurs in a wide range of diseases, including cancer, diabetes, and
Externí odkaz:
https://doaj.org/article/7d169bf0fd414700a3cf6ca7c1ca19b7
Autor:
Natalia Gomez-Navarro, Julija Maldutyte, Kristina Poljak, Sew-Yeu Peak-Chew, Jonathon Orme, Brittany J. Bisnett, Caitlin H. Lamb, Michael Boyce, Davide Gianni, Elizabeth A. Miller
Protein secretion is an essential cellular process that permits cell growth, movement and communication. Traffic of proteins within the eukaryotic secretory pathway is mediated by transport intermediates that bud from one compartment, populated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c254111bf93abe231f5d61061a89ba
Autor:
Brett M Condon, Timothy J. Smith, Caitlin H. Lamb, George R. Georgiou, Duc T. Huynh, Jimin Hu, Noah A. Linhart, Michael Boyce, Jingyi Bai, Brittany J. Bisnett
Publikováno v:
Glycobiology
O-linked β-N-acetylglucosamine (O-GlcNAc) is a dynamic form of intracellular glycosylation common in animals, plants and other organisms. O-GlcNAcylation is essential in mammalian cells and is dysregulated in myriad human diseases, such as cancer, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d066f01f7582221bc1e246d91374a2
https://europepmc.org/articles/PMC8457363/
https://europepmc.org/articles/PMC8457363/
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
The coat protein complex II (COPII) mediates forward trafficking of protein and lipid cargoes from the endoplasmic reticulum. COPII is an ancient and essential pathway in all eukaryotes and COPII dysfunction underlies a range of human diseases. Despi
Autor:
Anjon Audhya, Timothy J. Smith, Ela W. Knapik, Michael G. Hanna, Gokhan Unlu, Brett M Condon, Nathan J. Cox, Thomas R. Meister, Abhishek Chhetri, Peter M Luo, Erik J. Soderblom, Brittany J. Bisnett, Michael Boyce
Publikováno v:
Biochemistry. 57:91-107
The COPII coat complex, which mediates secretory cargo trafficking from the endoplasmic reticulum, is a key control point for subcellular protein targeting. Because misdirected proteins cannot function, protein sorting by COPII is critical for establ
Autor:
Timothy J. Smith, Po-Han Chen, Farhan Khan, Priscila F. Siesser, Michael Boyce, Maxwell Hogue, Brittany J. Bisnett, Jen-Tsan Chi, Jeffrey R. Marks, Michael B. Major, Flora Tang, Erik J. Soderblom, Jianli Wu, Benjamin M. Swarts
Publikováno v:
The EMBO Journal. 36:2233-2250
O‐GlcNAcylation is an essential, nutrient‐sensitive post‐translational modification, but its biochemical and phenotypic effects remain incompletely understood. To address this question, we investigated the global transcriptional response to per
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Timothy J. Smith, Nathan J. Cox, Erik J. Soderblom, Peter M Luo, Brittany J. Bisnett, Michael Boyce
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Frontiers in Endocrinology
Frontiers in Endocrinology
O-linked β-N-acetylglucosamine (O-GlcNAc) is an abundant and essential intracellular form of protein glycosylation in animals and plants. In humans, dysregulation of O-GlcNAcylation occurs in a wide range of diseases, including cancer, diabetes, and
Autor:
Andrew J. Rouff, Jack T. Bragg, Brittany J. Bisnett, Margot G. Paulick, Terence S. Fu, Sudhir Khetan, Hannah K. D'Ambrosio, Caroline A. Gorka, Michael Boyce, Faraz A. Khan, Joshua T. Rose, Timothy J. Smith
Publikováno v:
Chembiochem : a European journal of chemical biology. 18(18)
Trehalose is a disaccharide produced by many organisms to better enable them to survive environmental stresses, including heat, cold, desiccation, and reactive oxygen species. Mammalian cells do not naturally biosynthesize trehalose; however, when in