Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Brittany Dobson"'
Autor:
Alexandra D. Zaitsev, Marcie A. Glicksman, Ross L. Stein, Brittany Dobson, Ken Auerbach, Zhenyu Yue, Min Liu, Kathleen Seyb, Shibu M. Poulose, Eli R. Schuman, Gregory D. Cuny
Publikováno v:
Analytical Biochemistry. 404:186-192
LRRK2 is a large and complex protein that possesses kinase and GTPase activities and has emerged as the most relevant player in PD pathogenesis possibly through a toxic gain-of-function mechanism. Kinase activity is a critical component of LRRK2 func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1355d152d1ee8eb13257db35da4c0ab
https://doi.org/10.1016/j.ab.2010.05.033
https://doi.org/10.1016/j.ab.2010.05.033
Publikováno v:
Biochemistry. 49:2008-2017
Recent studies have identified mutations in the leucine-rich repeat kinase2 gene (LRRK2) in the most common familial forms and some sporadic forms of Parkinson's disease (PD). LRRK2 is a large and complex protein that possesses kinase and GTPase acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5cdf60b96a81e29d705eddd737adcb
https://doi.org/10.1021/bi901851y
https://doi.org/10.1021/bi901851y
Autor:
Kenneth S. Kosik, Kenneth Auerbach, Ross L. Stein, Gregory D. Cuny, Marcie A. Glicksman, Min Liu, Brittany Dobson
Publikováno v:
Current Alzheimer research. 4(5)
Cyclin-dependent kinase 5 (cdk5) is a member of the serine-threonine kinase family of cyclin-dependent kinases. This family is known for its role in the cell cycle, but cdk5 differs due to its interaction with activators p35 or p39, both abundant in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4384e6bc6b437ffcea655dfcda0a4a
https://pubmed.ncbi.nlm.nih.gov/18220519
https://pubmed.ncbi.nlm.nih.gov/18220519