Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Brittany D Needham"'
Autor:
Timothy R Sampson, Collin Challis, Neha Jain, Anastasiya Moiseyenko, Mark S Ladinsky, Gauri G Shastri, Taren Thron, Brittany D Needham, Istvan Horvath, Justine W Debelius, Stefan Janssen, Rob Knight, Pernilla Wittung-Stafshede, Viviana Gradinaru, Matthew Chapman, Sarkis K Mazmanian
Publikováno v:
eLife, Vol 9 (2020)
Amyloids are a class of protein with unique self-aggregation properties, and their aberrant accumulation can lead to cellular dysfunctions associated with neurodegenerative diseases. While genetic and environmental factors can influence amyloid forma
Externí odkaz:
https://doaj.org/article/a828d9d829724627bc449f3bc4f8d4bc
Autor:
John R Houser, Craig Barnhart, Daniel R Boutz, Sean M Carroll, Aurko Dasgupta, Joshua K Michener, Brittany D Needham, Ophelia Papoulas, Viswanadham Sridhara, Dariya K Sydykova, Christopher J Marx, M Stephen Trent, Jeffrey E Barrick, Edward M Marcotte, Claus O Wilke
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 8, p e1004400 (2015)
How do bacteria regulate their cellular physiology in response to starvation? Here, we present a detailed characterization of Escherichia coli growth and starvation over a time-course lasting two weeks. We have measured multiple cellular components,
Externí odkaz:
https://doaj.org/article/9de889c5ee104d68a308ff43690012fc
Autor:
Ina Nemet, Masanori Funabashi, Xinmin S. Li, Mohammed Dwidar, Naseer Sangwan, Sarah M. Skye, Kymberleigh A. Romano, Tomas Cajka, Brittany D. Needham, Sarkis K. Mazmanian, Adeline M. Hajjar, Federico E. Rey, Oliver Fiehn, W. H. Wilson Tang, Michael A. Fischbach, Stanley L. Hazen
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTp-Cresol sulfate (pCS) and indoxyl sulfate (IS), gut microbiome-derived metabolites, are traditionally associated with cardiovascular disease (CVD) risks in the setting of impaired kidney function. While pharmacologic provision of pCS or IS c
Externí odkaz:
https://doaj.org/article/b42c9dbc2abc4d00ac418c59c42a7a26
Autor:
Joseph C. Boktor, Mark D. Adame, Destanie R. Rose, Cynthia M. Schumann, Karl D. Murray, Melissa D. Bauman, Milo Careaga, Sarkis K. Mazmanian, Paul Ashwood, Brittany D. Needham
Publikováno v:
Molecular psychiatry, vol 27, iss 12
Mol Psychiatry
Mol Psychiatry
Epidemiological evidence implicates severe maternal infections as risk factors for neurodevelopmental disorders, such as ASD and schizophrenia. Accordingly, animal models mimicking infection during pregnancy, including the maternal immune activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871944e03223b1a96446dedd15fceb21
https://escholarship.org/uc/item/51r9k74s
https://escholarship.org/uc/item/51r9k74s
Autor:
James T. Morton, Dong-Min Jin, Robert H. Mills, Yan Shao, Gibraan Rahman, Daniel McDonald, Kirsten Berding, Brittany D. Needham, María Fernanda Zurita, Maude David, Olga V. Averina, Alexey S. Kovtun, Antonio Noto, Michele Mussap, Mingbang Wang, Daniel N. Frank, Ellen Li, Wenhao Zhou, Vassilios Fanos, Valery N. Danilenko, Dennis P. Wall, Paúl Cárdenas, Manuel E. Baldeón, Ramnik J. Xavier, Sarkis K. Mazmanian, Rob Knight, Jack A. Gilbert, Sharon M. Donovan, Trevor D. Lawley, Bob Carpenter, Richard Bonneau, Gaspar Taroncher-Oldenburg
Autism is a highly heritable neurodevelopmental disorder characterized by heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut-brain axis (GBA) has been implicated in autism, with dozens of cross-sectional microbio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afbe9e8ee0b342e57dec4a0489634748
https://doi.org/10.1101/2022.02.25.482050
https://doi.org/10.1101/2022.02.25.482050
Publikováno v:
Nature Reviews Neuroscience. 21:717-731
Mounting evidence suggests that the gut microbiome impacts brain development and function. Gut-brain connections may be mediated by an assortment of microbial molecules that are produced in the gastrointestinal tract, which can subsequently permeate
Autor:
Brittany D. Needham, Wei Li Wu, Catherine E. Schretter, Sarkis K. Mazmanian, Jacob T. Barlow, Viviana Gradinaru, James Ousey, Mark D. Adame, Tzu Ting Lai, Chia Wei Liou, Yuan Yuan Lin, Madelyn I. Wang, Reem Abdel-Haq, Weiyi Tang, Gil Sharon, Keith Beadle, Tzu Hsuan Yao, Rustem F. Ismagilov
Publikováno v:
Nature
Social interactions among animals mediate essential behaviours, including mating, nurturing, and defence1,2. The gut microbiota contribute to social activity in mice3,4, but the gut–brain connections that regulate this complex behaviour and its und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4fcbeeee454a97e8298dbbda5532894
https://resolver.caltech.edu/CaltechAUTHORS:20210706-202344110
https://resolver.caltech.edu/CaltechAUTHORS:20210706-202344110
Autor:
Brittany D. Needham, Masanori Funabashi, Mark D. Adame, Zhuo Wang, Joseph C. Boktor, Jillian Haney, Wei-Li Wu, Claire Rabut, Mark S. Ladinsky, Son-Jong Hwang, Yumei Guo, Qiyun Zhu, Jessica A. Griffiths, Rob Knight, Pamela J. Bjorkman, Mikhail G. Shapiro, Daniel H. Geschwind, Daniel P. Holschneider, Michael A. Fischbach, Sarkis K. Mazmanian
Publikováno v:
Nature, vol 602, iss 7898
Nature
Nature
Integration of sensory and molecular inputs from the environment shapes animal behaviour. A major site of exposure to environmental molecules is the gastrointestinal tract, in which dietary components are chemically transformed by the microbiota1 and
Autor:
Taren Thron, Sarkis K. Mazmanian, Mark S. Ladinsky, István T. Horváth, Anastasiya Moiseyenko, Neha Jain, Viviana Gradinaru, Rob Knight, Gauri G. Shastri, Timothy R. Sampson, Pernilla Wittung-Stafshede, Brittany D. Needham, Collin Challis, Matthew George Chapman, Stefan Janssen, Justine W. Debelius
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Amyloids are a class of protein with unique self-aggregation properties, and their aberrant accumulation can lead to cellular dysfunctions associated with neurodegenerative diseases. While genetic and environmental factors can influence amyloid forma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f412538818882f976d0c42055e52f4e
https://escholarship.org/uc/item/1nh000p8
https://escholarship.org/uc/item/1nh000p8
Autor:
Matthew George Chapman, Brittany D. Needham, Rob Knight, Collin Challis, Stefan Janssen, István T. Horváth, Anastasiya Moiseyenko, Pernilla Wittung-Stafshede, Neha Jain, Sarkis K. Mazmanian, Justine W. Debelius, Viviana Gradinaru, Gauri G. Shastri, Timothy R. Sampson, Taren Thron, Mark S. Ladinsky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993ab106121d07e13dc835fab459f2cf
https://doi.org/10.7554/elife.53111.sa2
https://doi.org/10.7554/elife.53111.sa2