Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Brittany C. Paporello"'
Publikováno v:
The Protein Journal. 32:337-342
PEGylation is a technology commonly used to enhance the bioavailability of therapeutic proteins in patients. Reductive alkylation of a protein amino terminal alpha amine in the presence of a polyethylene glycol (PEG) chain derivatized with propionald
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6102ae3e671d7a1475afd4ac6184e6c0
https://doi.org/10.1007/s10930-013-9491-4
https://doi.org/10.1007/s10930-013-9491-4
Autor:
Gulesi Ayanoglu, Erin Murphy, Scott P. Turner, Amy M Beebe, Ivan H. Chan, John B. Mumm, Venkataraman Sriram, Xueqing Zhang, Catherine Sheppard, Jeff Grein, Beth Basham, Martin Oft, Satya Medicherla, Jan Emmerich, Melanie A. Kleinschek, Lingling Wu, Michael Judo, Steven J. Blaisdell, Terrill K. McClanahan, Susan Cannon-Carlson, John L. Langowski, Danling Gu, Kyu Hong, Wolfgang Seghezzi, Smita Mauze, Brittany C. Paporello, Bela Desai, Saraswathi Naravula, Jie Dai, Drake LaFace, Collette M. Cutler
Publikováno v:
Cancer Cell. 20(6):781-796
Summary Tumor immune surveillance and cancer immunotherapies are thought to depend on the intratumoral infiltration of activated CD8 + T cells. Intratumoral CD8 + T cells are rare and lack activity. IL-10 is thought to contribute to the underlying im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be7a3a8453fea6fe1ae6913680436ca
Publikováno v:
Analytical biochemistry. 439(2)
A method capable of detecting both native and scrambled disulfide bonds has been established. Nonreduced protein digests were separated using a reversed-phase C18 column, partially reduced by post-column addition of a reducing reagent, and then analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fe56f82b85eda03a6816c492522fe6
https://pubmed.ncbi.nlm.nih.gov/23639491
https://pubmed.ncbi.nlm.nih.gov/23639491
Publikováno v:
Analytical biochemistry. 436(1)
Cyclization of N-terminal glutamine to pyroglutamate is a common modification of recombinant monoclonal antibodies that has often been identified by liquid chromatography mass spectrometry (LC-MS) analysis using separated fractions. An alternative ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07951f0227480cda746bcbaa137727a5
https://pubmed.ncbi.nlm.nih.gov/23357233
https://pubmed.ncbi.nlm.nih.gov/23357233