Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brittany Brookner"'
Publikováno v:
J Mol Diagn
Many patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency have CAH-X syndrome, a connective tissue dysplasia consistent with hypermobility-type Ehlers-Danlos syndrome due to a contiguous gene deletion involving the adja
Autor:
Adina F. Turcu, Smita Jha, Richard J. Auchus, Brittany Brookner, Deborah P. Merke, Ninet Sinaii
Publikováno v:
J Endocr Soc
Context Serum 17-hydroxyprogesterone (17OHP) and androstenedione (A4) are the conventional biomarkers used to assess disease control in patients with 21-hydroxylase deficiency (21OHD). However, discrepancy between the two is not uncommon, limiting in
Autor:
Deborah P. Merke, Maggie Dwiggins, Kylie Fowler, Brittany Brookner, Veronica Gomez-Lobo, Padmasree Veeraraghavan
Publikováno v:
J Endocr Soc
Context 46,XX patients with classic congenital adrenal hyperplasia (CAH) are exposed to elevated androgens in utero causing varying levels of virilization. The majority undergo feminizing genitoplasty early in life, with potential impact on sexual fu
Autor:
Adina F. Turcu, Brittany Brookner, Padmasree Veeraraghavan, Ashwini Mallappa, Ninet Sinaii, Smita Jha, Deborah P. Merke, Richard J. Auchus
Publikováno v:
Journal of the Endocrine Society
Background 21-hydroxylase-deficiency (21OHD) accounts for more than 95% of CAH cases. Serum 17-hydroxyprogesteron (17OHP) and androstenedione (A4) are traditional biomarkers for monitoring therapy. While generally there is good linear correlation bet
Autor:
Megan Startzell, Richard J. Auchus, Rebecca J. Brown, Deborah P. Merke, Adina F. Turcu, Brittany Brookner, Smita Jha, Brent Samuel Abel
Publikováno v:
Journal of the Endocrine Society
Background Patients with severe insulin resistance have ovarian hyperthecosis, high testosterone (T) and minimal adipose tissue. Recent studies have found elevated levels of 11-oxygenated (11-oxy) androgens in women with polycystic ovary syndrome (PC
Autor:
Maggie Dwiggins, Padmasree Veeraraghavan, Kathleen Bren, Deborah P. Merke, Brittany Brookner, Kylie G. Fowler, Veronica Gomez-Lobo
Publikováno v:
Journal of Pediatric and Adolescent Gynecology. 32:238