Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Brittany Baur"'
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Cancer risk by environmental exposure is modulated by an individual’s genetics and age at exposure. This age-specific period of susceptibility is referred to as the “Window of Susceptibility” (WOS). Rats have a similar WOS for developing breast
Externí odkaz:
https://doaj.org/article/f9995dd867954be6a4ec2e001051b5df
A Feature Selection Algorithm to Compute Gene Centric Methylation from Probe Level Methylation Data.
Autor:
Brittany Baur, Serdar Bozdag
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148977 (2016)
DNA methylation is an important epigenetic event that effects gene expression during development and various diseases such as cancer. Understanding the mechanism of action of DNA methylation is important for downstream analysis. In the Illumina Infin
Externí odkaz:
https://doaj.org/article/3ff0c489d34c422d803fcfea3dfa315f
Autor:
Mikhail Dozmorov, Maggie Marshall, Narmeen Rashid, Jacqueline Grible, Aaron D. Valentine, Amy Olex, Kavita Murthy, Abhijit Chakraborty, Joaquin Reyna, Daniela Salgado Figueroa, Da-Inn Lee, Brittany Baur, Sushmita Roy, Ferhat Ay, Chuck Harrell
Publikováno v:
Cancer Research. 83:P1-13
Changes in the three-dimensional (3D) structure of the genome are an emerging hallmark of cancer. Cancer-associated copy number variants and single nucleotide polymorphisms promote rewiring of chromatin loops, disruption of topologically associating
Publikováno v:
Journal of Science Policy & Governance. 18
To address changing climate patterns, cities in the US are expanding sustainable transportation options and implementing green infrastructure. Sustainable infrastructure projects help communities adapt, decrease CO2 emissions, promote community healt
Autor:
William Stafford Noble, Sushmita Roy, Yi Zhang, Jacob Schreiber, Junha Shin, Brittany Baur, Jun S. Song, Mohith Manjunath, Shilu Zhang
Understanding the impact of regulatory variants on complex phenotypes is a significant challenge because the genes and pathways that are targeted by such variants are typically unknown. Furthermore, a regulatory variant might influence a particular g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13d3ca420d8553f6bbdaa966f38b2e69
https://doi.org/10.1101/2021.08.29.458098
https://doi.org/10.1101/2021.08.29.458098
Publikováno v:
Journal of Science Policy & Governance. 18
Public transportation brings numerous benefits to communities when it provides people with mobility and access to opportunities. A well-designed and widely utilized system is required for regions to gain access to these benefits. Transit policies mus
Publikováno v:
Curr Opin Syst Biol
Transcriptional regulatory networks control context-specific gene expression patterns and play important roles in normal and disease processes. Advances in genomics are rapidly increasing our ability to measure different components of the regulation
Autor:
Daniel M. Gatti, Gregory R. Keele, Richard Mott, Joseph Fox, Brittany Baur, Jeremy W. Prokop, William Valdar, Maie Zagloul, Sanja Francic, Melanie Robinson, Michael J. Flister, Leilei Cui, Leah C. Solberg Woods, Hong He, Shawn Levy, Shirng Wern Tsaih, Michael Tschannen, Katie Holl, Karl W. Broman, Yunjung Kim, John Littrell, Aaron Deal
Publikováno v:
Obesity. 26:213-222
OBJECTIVE Obesity is a major risk factor for multiple diseases and is in part heritable, yet the majority of causative genetic variants that drive excessive adiposity remain unknown. Here, outbred heterogeneous stock (HS) rats were used in controlled
Autor:
Brittany Baur, Serdar Bozdag
Publikováno v:
Genomics. 109:233-240
Copy number amplifications and deletions that are recurrent in cancer samples harbor genes that confer a fitness advantage to cancer tumor proliferation and survival. One important challenge in computational biology is to separate the causal (i.e., d
Genome-wide association studies (GWAS) have hitherto identified several genetic variants associated with cancer susceptibility, but the molecular functions of these risk modulators remain largely uncharacterized. Recent studies have begun to uncover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059b4a58c50db9e29ab2185b3e8c82c7