Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Brittani L. Schnable"'
Autor:
Brittani L. Schnable, Matthew A. Schaich, Vera Roginskaya, Liam P. Leary, Tyler M. Weaver, Bret D. Freudenthal, Alexander C. Drohat, Bennett Van Houten
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Base excision repair is the main pathway involved in active DNA demethylation. 5-formylcytosine and 5-carboxylcytosine, two oxidized moieties of methylated cytosine, are recognized and removed by thymine DNA glycosylase (TDG) to generate an
Externí odkaz:
https://doaj.org/article/c5ab3255991842278bb091539a39a8ac
Autor:
Matthew A Schaich, Brittani L Schnable, Namrata Kumar, Vera Roginskaya, Rachel C Jakielski, Roman Urban, Zhou Zhong, Neil M Kad, Bennett Van Houten
Publikováno v:
Nucleic Acids Research. 51:e39-e39
Single-molecule characterization of protein–DNA dynamics provides unprecedented mechanistic details about numerous nuclear processes. Here, we describe a new method that rapidly generates single-molecule information with fluorescently tagged protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c613d6db38eb97ed0060c50810065b7
https://doi.org/10.1093/nar/gkad095
https://doi.org/10.1093/nar/gkad095
Publikováno v:
Biophysical Journal. 122:355a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe4e55cca9e3608cedbf18e2b553682c
https://doi.org/10.1016/j.bpj.2022.11.1967
https://doi.org/10.1016/j.bpj.2022.11.1967
Autor:
Bennett Van Houten, Sheila S. David, Chandrima Majumdar, Cindy Khuu, Matthew A. Schaich, Brittani L Schnable, Sunbok Jang, Simon C. Watkins
Publikováno v:
Nucleic acids research, vol 49, iss 14
Nucleic Acids Research
Nucleic Acids Research
The oxidative base damage, 8-oxo-7,8-dihydroguanine (8-oxoG) is a highly mutagenic lesion because replicative DNA polymerases insert adenine (A) opposite 8-oxoG. In mammalian cells, the removal of A incorporated across from 8-oxoG is mediated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdce6734987315aa70b2f26bec2dbeaa
https://escholarship.org/uc/item/7bs54080
https://escholarship.org/uc/item/7bs54080
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 43(5)
We highlight a recent study exploring the hand-off of UV damage to several key nucleotide excision repair (NER) proteins in the cascade: UV-DDB, XPC and TFIIH. The delicate dance of DNA repair proteins is choreographed by the dynamic hand-off of DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29667f3ad15599dc40a55274f82c937
https://pubmed.ncbi.nlm.nih.gov/33620094
https://pubmed.ncbi.nlm.nih.gov/33620094