Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Britta Nubbemeyer"'
Autor:
Britta Nubbemeyer, Ajay Abisheck Paul George, Toni Kühl, Anna Pepanian, Maximilian Steve Beck, Rahma Maghraby, Maryam Shetab Boushehri, Maximilian Muehlhaupt, Eva Marie Pfeil, Suvi Katariina Annala, Hermann Ammer, Diana Imhof, Dehua Pei
Publikováno v:
ACS Chemical Biology. 17:463-473
Chemical probes that specifically modulate the activity of heterotrimeric G proteins provide excellent tools for investigating G protein-mediated cell signaling. Herein, we report a family of selective peptidyl Gαi/s modulators derived from peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a955ac768369ef3b2d6a0ea1f1609b
https://doi.org/10.1021/acschembio.1c00929
https://doi.org/10.1021/acschembio.1c00929
Autor:
Thomas Schmitz, Arijit Biswas, Torsten Steinmetzer, Charlotte A. Bäuml, Ajay Abisheck Paul George, Diana Imhof, Oliver Ohlenschläger, Britta Nubbemeyer
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 880, p 880 (2021)
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 880, p 880 (2021)
The saliva of blood-sucking leeches contains a plethora of anticoagulant substances. One of these compounds derived from Haementeria ghilianii, the 66mer three-disulfide-bonded peptide tridegin, specifically inhibits the blood coagulation factor FXII
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00447b334538739852da17bddb4d5335
Autor:
Charlotte A. Bäuml, Evi Kostenis, Daniel Tietze, Tobias Benkel, Desireé Kaufmann, Max Crüsemann, Toni Kühl, Stefan Kehraus, Raphael Reher, Justin Patrick Odhiambo, Britta Nubbemeyer, Suvi Annala, Diana Imhof, Gabriele M. König, Pascal Heimer
Publikováno v:
ChemMedChem. 13:1634-1643
Direct targeting of intracellular Gα subunits of G protein-coupled receptors by chemical tools is a challenging task in current pharmacological studies and in the development of novel therapeutic approaches. In this study we analyzed novel FR900359-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05eccf1f87ce43469c8c7aa866a539f1
https://doi.org/10.1002/cmdc.201800304
https://doi.org/10.1002/cmdc.201800304
Autor:
Etilia Dolja, Thomas Schmitz, T. Hoang Luu, Patrick Rabe, Britta Nubbemeyer, Jeroen S. Dickschat, Jan Rinkel
Publikováno v:
Angewandte Chemie. 129:2820-2823
Die Mechanismen von zwei Diterpencyclasen aus Streptomyceten – eine mit unbekanntem Produkt, das als der spirocyclische Kohlenwasserstoff Spiroviolen identifiziert wurde, und eine mit dem bekannten Produkt Tsukubadien – wurden detailliert durch I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6323917b1ea9b29fbef9b86a6886fb75
https://doi.org/10.1002/ange.201612439
https://doi.org/10.1002/ange.201612439
Autor:
Etilia Dolja, Patrick Rabe, Jan Rinkel, Britta Nubbemeyer, Jeroen S. Dickschat, T. Hoang Luu, Thomas Schmitz
Publikováno v:
Angewandte Chemie International Edition. 56:2776-2779
The mechanisms of two diterpene cyclases from streptomycetes-one with an unknown product that was identified as the spirocyclic hydrocarbon spiroviolene and one with the known product tsukubadiene-were investigated in detail by isotope labeling exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b83589359dd3a52d87c1975f92f1b3
https://doi.org/10.1002/anie.201612439
https://doi.org/10.1002/anie.201612439
Autor:
Feng Chen, Patrick Rabe, Tobias G. Köllner, Jeroen S. Dickschat, Britta Nubbemeyer, Jan Rinkel
Publikováno v:
Angewandte Chemie International Edition. 55:15420-15423
Genome sequences of social amoebae reveal the presence of terpene cyclases (TCs) in these organisms. Two TCs from Dictyostelium discoideum converted farnesyl diphosphate into (2S,3R,6S,9S)-(-)-protoillud-7-ene and (3S)-(+)-asterisca-2(9),6-diene. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fcc7a02dc4939bc23356c2336a2cf23
https://doi.org/10.1002/anie.201608971
https://doi.org/10.1002/anie.201608971
Autor:
Raphael, Reher, Toni, Kühl, Suvi, Annala, Tobias, Benkel, Desireé, Kaufmann, Britta, Nubbemeyer, Justin Patrick, Odhiambo, Pascal, Heimer, Charlotte Anneke, Bäuml, Stefan, Kehraus, Max, Crüsemann, Evi, Kostenis, Daniel, Tietze, Gabriele M, König, Diana, Imhof
Publikováno v:
ChemMedChem. 13(16)
Direct targeting of intracellular Gα subunits of G protein-coupled receptors by chemical tools is a challenging task in current pharmacological studies and in the development of novel therapeutic approaches. In this study we analyzed novel FR900359-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad5b2c25cadac7732a1092426f0a5678
https://pubmed.ncbi.nlm.nih.gov/29873888
https://pubmed.ncbi.nlm.nih.gov/29873888
Autor:
Suvi Annala, Charlotte A. Bäuml, Justin Patrick Odhiambo, Toni Kühl, Diana Imhof, Max Crüsemann, Gabriele M. König, Raphael Reher, Pascal Heimer, Britta Nubbemeyer, Daniel Tietze, Tobias Benkel, Evi Kostenis, Stefan Kehraus, Desireé Kaufmann
Publikováno v:
ChemMedChem. 13:1617-1617
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7977a15d42fcbe184910e1cec13f644e
https://doi.org/10.1002/cmdc.201800521
https://doi.org/10.1002/cmdc.201800521