Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Britta Maecker-Kolhoff"'
Autor:
Sandra Nay, Nora Möhn, Lea Grote-Levi, Agnes Bonifacius, Mieke L. Saßmann, Kevin Karacondi, Sabine Tischer-Zimmermann, Henning Pöter, Nima Mahmoudi, Mike P. Wattjes, Britta Maecker-Kolhoff, Günter Höglinger, Britta Eiz-Vesper, Thomas Skripuletz
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Opportunistic viral infections in individuals with severe immunodeficiency can lead to fatal conditions such as progressive multifocal leukoencephalopathy (PML), for which treatment options are limited. These infections pose significant risks, especi
Externí odkaz:
https://doaj.org/article/42788b5c76d24749ba2d21114f3a2ad6
Autor:
Markus Benedikt Krueger, Agnes Bonifacius, Anna Christina Dragon, Maria Michela Santamorena, Björn Nashan, Richard Taubert, Ulrich Kalinke, Britta Maecker-Kolhoff, Rainer Blasczyk, Britta Eiz-Vesper
Publikováno v:
Transplant International, Vol 37 (2024)
Infectious complications, including widespread human cytomegalovirus (CMV) disease, frequently occur after hematopoietic stem cell and solid organ transplantation due to immunosuppressive treatment causing impairment of T-cell immunity. Therefore, in
Externí odkaz:
https://doaj.org/article/2510528d4a8b4271b8afed71ba6d2b25
Autor:
Anna Christina Dragon, Luca Marie Beermann, Melina Umland, Agnes Bonifacius, Chiara Malinconico, Louisa Ruhl, Patrik Kehler, Johanna Gellert, Lisa Weiß, Sarah Mayer-Hain, Katharina Zimmermann, Sebastian Riese, Felicitas Thol, Gernot Beutel, Britta Maecker-Kolhoff, Fumiichiro Yamamoto, Rainer Blasczyk, Axel Schambach, Michael Hust, Michael Hudecek, Britta Eiz-Vesper
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionChimeric antigen receptor-engineered T cells (CAR-Ts) are investigated in various clinical trials for the treatment of cancer entities beyond hematologic malignancies. A major hurdle is the identification of a target antigen with high exp
Externí odkaz:
https://doaj.org/article/46ba9e9337d34affb73dc677378f3afa
Autor:
Agnes Bonifacius, Britta Lamottke, Sabine Tischer-Zimmermann, Rebecca Schultze-Florey, Lilia Goudeva, Hans-Gert Heuft, Lubomir Arseniev, Rita Beier, Gernot Beutel, Gunnar Cario, Birgit Fröhlich, Johann Greil, Leo Hansmann, Justin Hasenkamp, Michaela Höfs, Patrick Hundsdoerfer, Edgar Jost, Kinan Kafa, Oliver Kriege, Nicolaus Kröger, Stephan Mathas, Roland Meisel, Michaela Nathrath, Mervi Putkonen, Sarina Ravens, Hans Christian Reinhardt, Elisa Sala, Martin G. Sauer, Clemens Schmitt, Roland Schroers, Nina Kristin Steckel, Ralf Ulrich Trappe, Mareike Verbeek, Daniel Wolff, Rainer Blasczyk, Britta Eiz-Vesper, Britta Maecker-Kolhoff
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
BACKGROUND Adoptive transfer of EBV-specific T cells can restore specific immunity in immunocompromised patients with EBV-associated complications.METHODS We provide results of a personalized T cell manufacturing program evaluating donor, patient, T
Externí odkaz:
https://doaj.org/article/90b7781e7f1547e9ab2df6d697ea2d7d
Autor:
Stefanie Maier, Miroslav Zivicnjak, Lorenz Grigull, Julia B. Hennermann, Charlotte Aries, Britta Maecker‐Kolhoff, Martin Sauer, Anibh M. Das, Rita Beier
Publikováno v:
JIMD Reports, Vol 63, Iss 4, Pp 371-378 (2022)
Abstract Mucopolysaccharidosis type I (MPS I) is an autosomal‐recessive metabolic disorder caused by an enzyme deficiency of lysosomal alpha‐l‐iduronidase (IDUA). Haematopoietic stem cell transplantation (HSCT) is the therapeutic option of choi
Externí odkaz:
https://doaj.org/article/52cea79855a24201b1c82a3a2e227ca8
Autor:
Birgit Burkhardt, Ulf Michgehl, Jonas Rohde, Tabea Erdmann, Philipp Berning, Katrin Reutter, Marius Rohde, Arndt Borkhardt, Thomas Burmeister, Sandeep Dave, Alexandar Tzankov, Martin Dugas, Sarah Sandmann, Falko Fend, Jasmin Finger, Stephanie Mueller, Nicola Gökbuget, Torsten Haferlach, Wolfgang Kern, Wolfgang Hartmann, Wolfram Klapper, Ilske Oschlies, Julia Richter, Udo Kontny, Mathias Lutz, Britta Maecker-Kolhoff, German Ott, Andreas Rosenwald, Reiner Siebert, Arend von Stackelberg, Brigitte Strahm, Wilhelm Woessmann, Martin Zimmermann, Myroslav Zapukhlyak, Michael Grau, Georg Lenz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Survival outcomes in Burkitt lymphoma differ between adult and paediatric patients. Here, the authors show differences in mutational frequencies between age groups, and a transition between mutational profiles which occurs between 25 and 40 years.
Externí odkaz:
https://doaj.org/article/23e93bbbffce48e295f023de9062df49
Autor:
Sabine Tischer-Zimmermann, Elisabeth Salzer, Tamires Bitencourt, Nelli Frank, Christine Hoffmann-Freimüller, Julia Stemberger, Britta Maecker-Kolhoff, Rainer Blasczyk, Volker Witt, Gerhard Fritsch, Wolfgang Paster, Thomas Lion, Britta Eiz-Vesper, René Geyeregger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAspergillus fumigatus (Asp) infections constitute a major cause of morbidity and mortality in patients following allogeneic hematopoietic stem cell transplantation (HSCT). In the context of insufficient host immunity, antifungal drugs sho
Externí odkaz:
https://doaj.org/article/e7579928abb04b849c28a29c88411a08
Autor:
Sabine Tischer-Zimmermann, Agnes Bonifacius, Maria Michela Santamorena, Philip Mausberg, Sven Stoll, Marius Döring, Ulrich Kalinke, Rainer Blasczyk, Britta Maecker-Kolhoff, Britta Eiz-Vesper
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn immunocompromised patients, Epstein-Barr virus (EBV) infection or reactivation is associated with increased morbidity and mortality, including the development of B-cell lymphomas. The first-line treatment consists of reduction of immun
Externí odkaz:
https://doaj.org/article/a835f60d638343ba896921dd0b07be9b
Autor:
Ulrich Baumann, Johannes H. Schulte, Jonathan P. Groß, Rita Beier, Marius Ludwig, Volker Wahn, Jörg Hofmann, Britta Maecker-Kolhoff, Martin Sauer, Petra Kaiser-Labusch, Negin Karimian, Ulrike Blume-Peytavi, Franziska Ghoreschi, Hagen Ott, Ludmila Perelygina, Christian Klemann, Oliver Blankenstein, Horst von Bernuth, Renate Krüger
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
We report two patients with DNA repair disorders (Artemis deficiency, Ataxia telangiectasia) with destructive skin granulomas, presumably triggered by live-attenuated rubella vaccinations. Both patients showed reduced naïve T cells. Rapid resolution
Externí odkaz:
https://doaj.org/article/74676d116b12464bbeaa7e1f70c43e0f
Autor:
Michael Koldehoff, Britta Eiz-Vesper, Britta Maecker-Kolhoff, Nina K. Steckel, Ulf Dittmer, Peter A. Horn, Monika Lindemann
Publikováno v:
Vaccines, Vol 11, Iss 4, p 845 (2023)
The BK virus (BKV) causes severe hemorrhagic cystitis in hematopoietic stem cell transplant (HSCT) recipients. To eliminate reactivated BKV, symptomatic patients can be treated with a reduction of the immunosuppressive therapy, with the antiviral dru
Externí odkaz:
https://doaj.org/article/ce9eeaa5f6fd4371b5c01a6f155e7ec2