Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Britta Frensch"'
Autor:
Britta Frensch, Thorsten Lechtenberg, Michel Kather, Zeynep Yunt, Martin Betschart, Bernd Kammerer, Steffen Lüdeke, Michael Müller, Jörn Piel, Robin Teufel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Rubromycin family of natural products belongs to aromatic polyketides with diverse bioactivities, but details of their biosynthesis are limited. Here, the authors report the complete in vitro reconstitution of enzymatic formation of the spiroketal mo
Externí odkaz:
https://doaj.org/article/2c66fdf660624127ac29372efbed73b9
Publikováno v:
Chemical Science. 13:7157-7164
The often complex control of bacterial natural product biosynthesis typically involves global and pathway-specific transcriptional regulators of gene expression, which often limits the yield of bioactive compounds under laboratory conditions. However
Autor:
Robin Teufel, David L. Zechel, Olga Tsypik, Britta Frensch, Thomas Paululat, Andreas Bechthold, Roman Makitrynskyy
Publikováno v:
Journal of the American Chemical Society. 142:5913-5917
The structural diversity of type II polyketides is largely generated by tailoring enzymes. In rishirilide biosynthesis by Streptomyces bottropensis, 13C-labeling studies previously implied extraordinary carbon backbone and side-chain rearrangements.
Autor:
Ralph Kluge, Hartmut Fuess, Irina Kempter, Britta Frensch, René Csuk, Jens Hartung, Thomas Kopf, Ingrid Svoboda
Publikováno v:
Tetrahedron. 70:1918-1927
Four diastereomers of 2-[(trimethylammonium)-methyl]-5-methyltetrahydrofuran-3-ol, trivially named isomuscarine, allo-isomuscarine, epi-isomuscarine, and epiallo-isomuscarine, were prepared as bromide salts from 2,4-like and 2,4-unlike diastereomers