Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Britta Eiz-Vesper"'
Autor:
Fawad Khan, Thomas R. Müller, Bahram Kasmapour, Mario Alberto Ynga-Durand, Britta Eiz-Vesper, Jens von Einem, Dirk H. Busch, Luka Cicin-Sain
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHuman Cytomegalovirus (HCMV) is a betaherpesvirus that causes severe disease in immunocompromised transplant recipients. Immunotherapy with CD8 T cells specific for HCMV antigens presented on HLA class-I molecules is explored as strategy
Externí odkaz:
https://doaj.org/article/5383d64b68704ffa9711620b48d0c27e
Autor:
Bibiana Costa, Jennifer Becker, Tobias Krammer, Felix Mulenge, Verónica Durán, Andreas Pavlou, Olivia Luise Gern, Xiaojing Chu, Yang Li, Luka Čičin-Šain, Britta Eiz-Vesper, Martin Messerle, Lars Dölken, Antoine-Emmanuel Saliba, Florian Erhard, Ulrich Kalinke
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Human cytomegalovirus (HCMV) is a widespread pathogen that in immunocompromised hosts can cause life-threatening disease. Studying HCMV-exposed monocyte-derived dendritic cells by single-cell RNA sequencing, we observe that most cells are en
Externí odkaz:
https://doaj.org/article/7e57f2fc99c0427a90c6d097bb173ff7
Autor:
Sandra Nay, Nora Möhn, Lea Grote-Levi, Agnes Bonifacius, Mieke L. Saßmann, Kevin Karacondi, Sabine Tischer-Zimmermann, Henning Pöter, Nima Mahmoudi, Mike P. Wattjes, Britta Maecker-Kolhoff, Günter Höglinger, Britta Eiz-Vesper, Thomas Skripuletz
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Opportunistic viral infections in individuals with severe immunodeficiency can lead to fatal conditions such as progressive multifocal leukoencephalopathy (PML), for which treatment options are limited. These infections pose significant risks, especi
Externí odkaz:
https://doaj.org/article/42788b5c76d24749ba2d21114f3a2ad6
Autor:
Markus Benedikt Krueger, Agnes Bonifacius, Anna Christina Dragon, Maria Michela Santamorena, Björn Nashan, Richard Taubert, Ulrich Kalinke, Britta Maecker-Kolhoff, Rainer Blasczyk, Britta Eiz-Vesper
Publikováno v:
Transplant International, Vol 37 (2024)
Infectious complications, including widespread human cytomegalovirus (CMV) disease, frequently occur after hematopoietic stem cell and solid organ transplantation due to immunosuppressive treatment causing impairment of T-cell immunity. Therefore, in
Externí odkaz:
https://doaj.org/article/2510528d4a8b4271b8afed71ba6d2b25
Autor:
Anna Christina Dragon, Luca Marie Beermann, Melina Umland, Agnes Bonifacius, Chiara Malinconico, Louisa Ruhl, Patrik Kehler, Johanna Gellert, Lisa Weiß, Sarah Mayer-Hain, Katharina Zimmermann, Sebastian Riese, Felicitas Thol, Gernot Beutel, Britta Maecker-Kolhoff, Fumiichiro Yamamoto, Rainer Blasczyk, Axel Schambach, Michael Hust, Michael Hudecek, Britta Eiz-Vesper
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionChimeric antigen receptor-engineered T cells (CAR-Ts) are investigated in various clinical trials for the treatment of cancer entities beyond hematologic malignancies. A major hurdle is the identification of a target antigen with high exp
Externí odkaz:
https://doaj.org/article/46ba9e9337d34affb73dc677378f3afa
Autor:
Agnes Bonifacius, Britta Lamottke, Sabine Tischer-Zimmermann, Rebecca Schultze-Florey, Lilia Goudeva, Hans-Gert Heuft, Lubomir Arseniev, Rita Beier, Gernot Beutel, Gunnar Cario, Birgit Fröhlich, Johann Greil, Leo Hansmann, Justin Hasenkamp, Michaela Höfs, Patrick Hundsdoerfer, Edgar Jost, Kinan Kafa, Oliver Kriege, Nicolaus Kröger, Stephan Mathas, Roland Meisel, Michaela Nathrath, Mervi Putkonen, Sarina Ravens, Hans Christian Reinhardt, Elisa Sala, Martin G. Sauer, Clemens Schmitt, Roland Schroers, Nina Kristin Steckel, Ralf Ulrich Trappe, Mareike Verbeek, Daniel Wolff, Rainer Blasczyk, Britta Eiz-Vesper, Britta Maecker-Kolhoff
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
BACKGROUND Adoptive transfer of EBV-specific T cells can restore specific immunity in immunocompromised patients with EBV-associated complications.METHODS We provide results of a personalized T cell manufacturing program evaluating donor, patient, T
Externí odkaz:
https://doaj.org/article/90b7781e7f1547e9ab2df6d697ea2d7d
Autor:
Sabine Tischer-Zimmermann, Elisabeth Salzer, Tamires Bitencourt, Nelli Frank, Christine Hoffmann-Freimüller, Julia Stemberger, Britta Maecker-Kolhoff, Rainer Blasczyk, Volker Witt, Gerhard Fritsch, Wolfgang Paster, Thomas Lion, Britta Eiz-Vesper, René Geyeregger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAspergillus fumigatus (Asp) infections constitute a major cause of morbidity and mortality in patients following allogeneic hematopoietic stem cell transplantation (HSCT). In the context of insufficient host immunity, antifungal drugs sho
Externí odkaz:
https://doaj.org/article/e7579928abb04b849c28a29c88411a08
Autor:
Sabine Tischer-Zimmermann, Agnes Bonifacius, Maria Michela Santamorena, Philip Mausberg, Sven Stoll, Marius Döring, Ulrich Kalinke, Rainer Blasczyk, Britta Maecker-Kolhoff, Britta Eiz-Vesper
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn immunocompromised patients, Epstein-Barr virus (EBV) infection or reactivation is associated with increased morbidity and mortality, including the development of B-cell lymphomas. The first-line treatment consists of reduction of immun
Externí odkaz:
https://doaj.org/article/a835f60d638343ba896921dd0b07be9b
Autor:
Martijn Zoodsma, Aline H. de Nooijer, Inge Grondman, Manoj Kumar Gupta, Agnes Bonifacius, Valerie A. C. M. Koeken, Emma Kooistra, Gizem Kilic, Ozlem Bulut, Nina Gödecke, Nico Janssen, Matthijs Kox, Jorge Domínguez-Andrés, Adriaan J. van Gammeren, Anton A. M. Ermens, Andre J. A. M. van der Ven, Peter Pickkers, Rainer Blasczyk, Georg M. N. Behrens, Frank L. van de Veerdonk, Leo A. B. Joosten, Cheng-Jian Xu, Britta Eiz-Vesper, Mihai G. Netea, Yang Li
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The ongoing Coronavirus Disease 2019 (COVID-19) pandemic is caused by the highly infectious Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). There is an urgent need for biomarkers that will help in better stratification of patients and c
Externí odkaz:
https://doaj.org/article/bf3709bd973c499892bbf04526a3acf9
Autor:
Julia K. Bialek-Waldmann, Sabine Domning, Ruth Esser, Wolfgang Glienke, Mira Mertens, Krasimira Aleksandrova, Lubomir Arseniev, Suresh Kumar, Andreas Schneider, Johannes Koenig, Sebastian J. Theobald, Hsin-Chieh Tsay, Angela D.A. Cornelius, Agnes Bonifacius, Britta Eiz-Vesper, Constanca Figueiredo, Dirk Schaudien, Steven R. Talbot, Andre Bleich, Loukia M. Spineli, Constantin von Kaisenberg, Caren Clark, Rainer Blasczyk, Michael Heuser, Arnold Ganser, Ulrike Köhl, Farzin Farzaneh, Renata Stripecke
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 621-641 (2021)
Acute myeloid leukemia (AML) patients with minimal residual disease and receiving allogeneic hematopoietic stem cell transplantation (HCT) have poor survival. Adoptive administration of dendritic cells (DCs) presenting the Wilms tumor protein 1 (WT1)
Externí odkaz:
https://doaj.org/article/aa4cf9a177124c648d5410e058e734cf