Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Britta B. Thestrup"'
Publikováno v:
Wojdacz, T K, Thestrup, B B, Cold, S, Overgaard, J & Hansen, L L 2011, ' No difference in the frequency of locus-specific methylation in the peripheral blood DNA of women diagnosed with breast cancer and age-matched controls ', Future Oncology, vol. 7, no. 12, pp. 1451-5 . https://doi.org/10.2217/fon.11.123
There is no doubt that aberrant somatic (tumor-specific) methylation significantly contributes to the carcinogenic process. However, the question of the relevance of methylation pattern changes, acquired by individuals during their development and li
Publikováno v:
Diagnostic Pathology
Wojdacz, T K, Thestrup, B B, Overgaard, J & Hansen, L L 2011, ' Methylation of cancer related genes in tumor and peripheral blood DNA from the same breast cancer patient as two independent events ', Diagnostic Pathology, vol. 6, no. 1, pp. 116 . https://doi.org/10.1186/1746-1596-6-116
Diagnostic Pathology, Vol 6, Iss 1, p 116 (2011)
Wojdacz, T K, Thestrup, B B, Overgaard, J & Hansen, L L 2011, ' Methylation of cancer related genes in tumor and peripheral blood DNA from the same breast cancer patient as two independent events ', Diagnostic Pathology, vol. 6, no. 1, pp. 116 . https://doi.org/10.1186/1746-1596-6-116
Diagnostic Pathology, Vol 6, Iss 1, p 116 (2011)
Background Recently it has been suggested that acquisition of methylation of the BRCA1 promoter detectable in peripheral blood (PB) DNA, could give raise to development of breast cancer. In this study, we aimed to investigate a relationship between m
Autor:
Carsten Wiuf, Henrik Hager, Lasse Sommer Kristensen, Tomasz K. Wojdacz, Lise Lotte Hansen, Britta B. Thestrup
Publikováno v:
Kristensen, L S, Wojdacz, T K, Thestrup, B B, Wiuf, C H, Hager, H & Hansen, L L 2009, ' Quality assessment of DNA derived from up to 30 years old formalin fixed paraffin embedded (FFPE) tissue for PCR-based methylation analysis using SMART-MSP and MS-HRM ', B M C Cancer, vol. 9, no. 453, pp. 453 .
BMC Cancer
Aarhus University
BMC Cancer, Vol 9, Iss 1, p 453 (2009)
BMC Cancer
Aarhus University
BMC Cancer, Vol 9, Iss 1, p 453 (2009)
Background The High Resolution Melting (HRM) technology has recently been introduced as a rapid and robust analysis tool for the detection of DNA methylation. The methylation status of multiple tumor suppressor genes may serve as biomarkers for early
Autor:
Jens Overgaard, Johanne Agerlin Windeløv, Lise Lotte Hansen, Tine Engberg Damsgaard, Britta B. Thestrup, Tomasz K. Wojdacz
Publikováno v:
Cancer Research. 74:2308-2308
Breast cancer is a highly heterogeneous malignancy, which is best exemplified by the fact that despite similar clinical and pathological features large number breast cancer patients experience different outcome of the disease. Therefore there is an u
Autor:
Johanne Agerlin Windeløv, Tomasz K. Wojdacz, Lise Lotte Hansen, Tine Engberg Damsgaard, Britta B. Thestrup, Jens Overgaard
Publikováno v:
Breast Cancer Research : BCR
Wojdacz, T K, Windeløv, J A, Thestrup, B B, Damsgaard, T E, Overgaard, J & Hansen, L L 2014, ' Identification and characterization of locus specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis ', Breast Cancer Research (Online Edition), vol. 16, R17 . https://doi.org/10.1186/bcr3612
Wojdacz, T K, Windeløv, J A, Thestrup, B B, Damsgaard, T E, Overgaard, J & Hansen, L L 2014, ' Identification and characterization of locus specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis ', Breast Cancer Research (Online Edition), vol. 16, R17 . https://doi.org/10.1186/bcr3612
INTRODUCTION:Despite similar clinical and pathological features, large numbers of breast cancer patients experience different outcomes of the disease. This, together with the fact that the incidence of breast cancer is growing worldwide, emphasizes a
Autor:
Jens Overgaard, Lise Lotte Hansen, Tomasz K. Wojdacz, Tine Engberg Damsgaard, Britta B. Thestrup
Publikováno v:
Cancer Research. 72:1703-1703
Methylation is a process of regulation of gene expression. Methylation pattern changes are implicated in the pathology of cancer and other disorders but at the same time they can be used as biomarkers for clinical disease management. There are four p
Autor:
Tomasz K. Wojdacz, Lise Lotte Hansen, Lasse Sommer Kristensen, Britta B. Thestrup, Henrik Hager
Publikováno v:
Cancer Research. 70:4918-4918
Background: The High-Resolution Melting (HRM) technology has recently been introduced as a rapid and robust analysis tool for the detection of DNA methylation. The methylation status of multiple tumor suppressor genes may serve as biomarkers for earl
Autor:
Lasse Sommer Kristensen, Britta B. Thestrup, Lise Lotte Hansen, Tine Hørning Møller, Tomasz K. Wojdacz
Publikováno v:
Aarhus University
Wojdacz, T K, Møller, T H, Thestrup, B B, Kristensen, L S & Hansen, L L 2010, ' Limitations and advantages of MS-HRM and bisulfite sequencing for single locus methylation studies. ', Expert Review of Molecular Diagnostics, vol. 10, no. 5, pp. 575-580 .
Wojdacz, T K, Møller, T H, Thestrup, B B, Kristensen, L S & Hansen, L L 2010, ' Limitations and advantages of MS-HRM and bisulfite sequencing for single locus methylation studies. ', Expert Review of Molecular Diagnostics, vol. 10, no. 5, pp. 575-580 .
The methylation-sensitive high-resolution melting (MS-HRM) protocol, as described by Wojdacz and Dobrovic, enables detection of a methylated template in an unmethylated background, with sensitivity similar to that of methylation-specific PCR (MSP). F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb9daad176546cb6223e6ec62e30bcc
https://pure.au.dk/portal/en/publications/limitations-and-advantages-of-mshrm-and-bisulfite-sequencing-for-single-locus-methylation-studies(97a95f90-f886-11df-a891-000ea68e967b).html
https://pure.au.dk/portal/en/publications/limitations-and-advantages-of-mshrm-and-bisulfite-sequencing-for-single-locus-methylation-studies(97a95f90-f886-11df-a891-000ea68e967b).html