Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Britt I, Drögemöller"'
Autor:
Deanne Nixie R. Miao, MacKenzie A. P. Wilke, John Pham, Feryal Ladha, Mansumeet Singh, Janilyn Arsenio, Emilia Luca, Alain Dabdoub, Wejian Yang, Jun J. Yang, Britt I. Drögemöller
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-9 (2024)
Abstract Background Cisplatin-induced ototoxicity (CIO), characterized by irreversible and progressive bilateral hearing loss, is a prevalent adverse effect of cisplatin chemotherapy. Alongside clinical risk factors, genetic variants contribute to CI
Externí odkaz:
https://doaj.org/article/667b8ba4552f40ea9190cfb73b71c7f6
Autor:
Erika N. Scott, Galen E. B. Wright, Britt I. Drögemöller, Jafar S. Hasbullah, Erandika P. Gunaretnam, Fudan Miao, Amit P. Bhavsar, Fei Shen, Bryan P. Schneider, Bruce C. Carleton, Colin J. D. Ross
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract Anthracyclines are highly effective chemotherapeutic agents; however, their clinical utility is limited by severe anthracycline-induced cardiotoxicity (ACT). Genome-wide association studies (GWAS) have uncovered several genetic variants asso
Externí odkaz:
https://doaj.org/article/ef67d46dd6034a2687778555b536d940
Autor:
Jorge E. B. da Rocha, Houcemeddine Othman, Gerrit Botha, Laura Cottino, David Twesigomwe, Samah Ahmed, Britt I. Drögemöller, Faisal M. Fadlelmola, Philip Machanick, Mamana Mbiyavanga, Sumir Panji, Galen E. B. Wright, Clement Adebamowo, Mogomotsi Matshaba, Michéle Ramsay, Gustave Simo, Martin C. Simuunza, Caroline T. Tiemessen, Sandra Baldwin, Mathias Chiano, Charles Cox, Annette S. Gross, Pamela Thomas, Francisco-Javier Gamo, Scott Hazelhurst
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Introduction: Investigating variation in genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are key to characterizing pharmacogenomic (PGx) relationships. ADME gene variation is relatively well characterized in
Externí odkaz:
https://doaj.org/article/99ceb47f7191413f978d2697836a9538
Autor:
Sarah M. Lyle, Samah Ahmed, Jason E. Elliott, Elisabet Stener-Victorin, Mark W. Nachtigal, Britt I. Drögemöller
Publikováno v:
Journal of Human Genetics. 68:347-353
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd04c24c80576d4ae09d089204d008db
https://doi.org/10.1038/s10038-023-01120-w
https://doi.org/10.1038/s10038-023-01120-w
Autor:
Cristina Rodriguez‐Antona, Jessica L. Savieo, Volker M. Lauschke, Katrin Sangkuhl, Britt I. Drögemöller, Danxin Wang, Ron H. N. van Schaik, Andrei A. Gilep, Arul P. Peter, Erin C. Boone, Bronwyn E. Ramey, Teri E. Klein, Michelle Whirl‐Carrillo, Victoria M. Pratt, Andrea Gaedigk
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:1159-1171
The Pharmacogene Variation Consortium (PharmVar) catalogs star (*) allele nomenclature for the polymorphic human CYP3A5 gene. Genetic variation within the CYP3A5 gene locus impacts the metabolism of several clinically important drugs, including the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b850582462fe0001640da5796eadb7
https://doi.org/10.1002/cpt.2563
https://doi.org/10.1002/cpt.2563
Autor:
Catrina M. Loucks, Jennifer J. Lin, Jessica N. Trueman, Britt I. Drögemöller, Galen E. B. Wright, Wan‐Chun Chang, Kathy H. Li, Eric M. Yoshida, Jo‐Ann Ford, Samuel S. Lee, Pam Crotty, Richard B. Kim, Bandar Al‐Judaibi, Ute I. Schwarz, Alnoor Ramji, Jeanette F. Farivar, Edward Tam, Lori Lee Walston, Colin J. D. Ross, Bruce C. Carleton
Publikováno v:
Liver International. 42:796-808
According to pivotal clinical trials, cure rates for sofosbuvir-based antiviral therapy exceed 96%. Treatment failure is usually assumed to be because of virological resistance-associated substitutions or clinical risk factors, yet the role of patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465b554b7658b273b9d5cc50cce82eae
https://doi.org/10.1111/liv.15175
https://doi.org/10.1111/liv.15175
Autor:
Colin J.D. Ross, Bruce C. Carleton, Karen A. Gelmon, Michael R. Hayden, Philippe L. Bedard, Christian K. Kollmannsberger, Daniel J. Renouf, Geoffrey Liu, Galen E.B. Wright, José G. Monzon, Carol Critchley, Beth Brooks, Britt I. Drögemöller
Table S1 provides a summary of the genetic association results in the European only cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85c21eaad2879e0c986dc21e2c768eb
https://doi.org/10.1158/1078-0432.22464969
https://doi.org/10.1158/1078-0432.22464969
Autor:
Colin J.D. Ross, Bruce C. Carleton, Karen A. Gelmon, Michael R. Hayden, Philippe L. Bedard, Christian K. Kollmannsberger, Daniel J. Renouf, Geoffrey Liu, Galen E.B. Wright, José G. Monzon, Carol Critchley, Beth Brooks, Britt I. Drögemöller
Figure S4 provides examples of audiogram configurations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9332c9bd1ae298f8b3bc001d431858
https://doi.org/10.1158/1078-0432.22464972
https://doi.org/10.1158/1078-0432.22464972
Autor:
Colin J.D. Ross, Bruce C. Carleton, Karen A. Gelmon, Michael R. Hayden, Philippe L. Bedard, Christian K. Kollmannsberger, Daniel J. Renouf, Geoffrey Liu, Galen E.B. Wright, José G. Monzon, Carol Critchley, Beth Brooks, Britt I. Drögemöller
Purpose: Adverse drug reactions such as ototoxicity, which occurs in approximately one-fifth of adult patients who receive cisplatin treatment, can incur large socioeconomic burdens on patients with testicular cancer who develop this cancer during ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19ecc34e7e0205be4948d4651b5603f
https://doi.org/10.1158/1078-0432.c.6525879
https://doi.org/10.1158/1078-0432.c.6525879
Autor:
Kristen M, Gibson, Britt I, Drögemöller, Dirk, Foell, Susanne M, Benseler, Jinko, Graham, Robert E W, Hancock, Raashid A, Luqmani, David A, Cabral, Kelly L, Brown, Colin J, Ross, Heidi, Stapp
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare, life-threatening inflammation of blood vessels that can affect both adults and children. Compared to adult-onset disease, AAV is especially rare in children with an an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3321248f37e8b0d4f584b89a3ca2f403
https://pubmed.ncbi.nlm.nih.gov/36530128
https://pubmed.ncbi.nlm.nih.gov/36530128