Genetic and phenotypic selection affect natural (auto-) antibody reactivity of chickens.

Autor: Britt G de Jong, Aart Lammers, Leonora A A Oberendorf, Mike G B Nieuwland, Huub F J Savelkoul, Henk K Parmentier

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e72276 (2013)

Specificity, antibody isotype distribution and levels of natural antibodies (NAb) may be potential informative parameters for immune mediated natural disease resistance, immune modulation, and maintenance of physiological homeostasis. A large proport

Externí odkaz: https://doaj.org/article/5b53f1d888ba479880e3b6031fe50718

Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age

Autor: Hanna IJspeert, Menno C. van Zelm, Bruno G. Loos, Britt G. De Jong, Lemelinda Marques, Jacques J.M. van Dongen, Mirjam van der Burg

Publikováno v: de Jong, B G, IJspeert, H, Marques, L, van der Burg, M, van Dongen, J J M, Loos, B G & van Zelm, M C 2017, ' Human IgG2-and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age ', Immunology and cell biology, vol. 95, no. 9, pp. 744-752 . https://doi.org/10.1038/icb.2017.43
Immunology and Cell Biology, 95(9), 744-752. Springer Nature
Immunology & Cell Biology, 95(9), 744-752. John Wiley & Sons Inc.
Immunology and Cell Biology
Immunology and cell biology, 95(9), 744-752. Nature Publishing Group

The mechanisms involved in sequential immunoglobulin G (IgG) class switching are still largely unknown. Sequential IG class switching is linked to higher levels of somatic hypermutation (SHM) in vivo, but it remains unclear if these are generated tem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3892415ebd399954f65868c64862f5
https://research.vu.nl/en/publications/77770ed4-07e9-46d2-bbf2-ab18e9a07659