Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Britt Duijndam"'
Autor:
Paola Nolé, Britt Duijndam, Adam Stenman, C Christofer Juhlin, Mikael Kozyra, Catharina Larsson, Magnus Ingelman-Sundberg, Inger Johansson
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162379 (2016)
Human cytochome P450 2W1 (CYP2W1) enzyme is expressed in fetal colon and in colon tumors. The level of expression is higher in colon metastases than in the parent tumors and the enzyme is a possible drug target for treatment of colorectal cancer, as
Externí odkaz:
https://doaj.org/article/ff9c1d5a9fd742749d354195a0e247fb
Autor:
Annemieke Aartsma-Rus, Willeke van Roon-Mom, Marlen Lauffer, Christine Siezen, Britt Duijndam, Tineke Coenen-de Roo, Rebecca Schüle, Matthis Synofzik, Holm Graessner
Publikováno v:
RNA 29(4), 446-454 (2023). doi:10.1261/rna.079540.122
Splice-modulating antisense oligonucleotides (ASOs) offer treatment options for rare neurological diseases, including those with very rare mutations, where patient-specific, individualized ASOs have to be developed. Inspired by the development of mil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d05f57802f70ee534d3b4f2e7de8dbe
https://pub.dzne.de/record/257309
https://pub.dzne.de/record/257309
Autor:
Tineke van den Hoorn, Jan Willem van der Laan, Peter Bouwman, Annabel Goudriaan, Sylvia E. Le Dévédec, Wanda van der Stel, Bob van de Water, Britt Duijndam
Publikováno v:
Toxicological Sciences
Toxicological Sciences, 181(2), 187-198. Oxford University Press (OUP)
Toxicological Sciences, 181(2), 187-198. Oxford University Press (OUP)
Estrogen receptor alpha (ERα) belongs to the nuclear hormone receptor family of ligand-inducible transcription factors and regulates gene networks in biological processes such as cell growth and proliferation. Disruption of these networks by chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc2ab5cb7a285a46135273e8519eebd
https://doi.org/10.1093/toxsci/kfab037
https://doi.org/10.1093/toxsci/kfab037
Changing the field of carcinogenicity testing of human pharmaceuticals by emphasizing mode of action
Autor:
Tineke van den Hoorn, Bob van de Water, Ruud Woutersen, Jan Willem van der Laan, Britt Duijndam
Publikováno v:
Current Opinion in Toxicology, 3, 55-61
Lifetime testing for carcinogenicity of pharmaceuticals in rodents has been a controversial issue since the start of the International Conference on Harmonisation in 1990. Since 2010 the debate reached a new level following the proposal that a negati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437b5c3071632ccd92d54e5610448e68
https://doi.org/10.1016/j.cotox.2017.06.004
https://doi.org/10.1016/j.cotox.2017.06.004
Autor:
Britt Duijndam, Paola Nolé, Adam Stenman, Mikael Kozyra, Catharina Larsson, C. Christofer Juhlin, Magnus Ingelman-Sundberg, Inger Johansson
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162379 (2016)
PLoS ONE
PLoS ONE
Human cytochome P450 2W1 (CYP2W1) enzyme is expressed in fetal colon and in colon tumors. The level of expression is higher in colon metastases than in the parent tumors and the enzyme is a possible drug target for treatment of colorectal cancer, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f6c9e01a16dc4db42f0c8a51a50191
http://europepmc.org/articles/PMC5012573?pdf=render
http://europepmc.org/articles/PMC5012573?pdf=render