Corrigendum to "TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43" [Neurobiology of disease Volume 193, April 2024, 106437].

Autor: Godoy-Corchuelo JM; Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain., Ali Z; Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain; MRC Harwell Institute, Oxfordshire, UK., Brito Armas JM; Unidad de Investigación, Hospital Universitario de Canarias, ITB-ULL and CIBERNED, La Laguna, Spain., Martins-Bach AB; Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, UK., García-Toledo I; Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain., Fernandez-Beltrán LC; Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain; Department of Medicine, Universidad Complutense de Madrid, Madrid, Spain., Lopez-Carbonero JI; Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain., Bascunana P; Brain Mapping Group, Hospital Clínico San Carlos, IdISSC, Madrid, Spain., Spring S; Mouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada., Jimenez-Coca I; Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain., Muñozde Bustillo Alfaro RA; Unidad de Investigación, Hospital Universitario de Canarias, ITB-ULL and CIBERNED, La Laguna, Spain., Sanchez-Barrena MJ; Department of Crystallography and Structural Biology, Institute of Physical Chemistry 'Blas Cabrera', CSIC, Madrid, Spain., Nair RR; MRC Harwell Institute, Oxfordshire, UK; Nucleic Acid Therapy Accelerator (NATA), Harwell Campus, Oxfordshire, UK., Nieman BJ; Mouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, Canada., Lerch JP; Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, UK., Miller KL; Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, UK., Ozdinler HP; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Fisher EMC; Department of Neuromuscular Diseases, UCL Queen Square Motor Neuron Disease Centre, UCL, Institute of Neurology, London, UK., Cunningham TJ; MRC Harwell Institute, Oxfordshire, UK; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, UK., Acevedo-Arozena A; Unidad de Investigación, Hospital Universitario de Canarias, ITB-ULL and CIBERNED, La Laguna, Spain., Corrochano S; Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain; MRC Harwell Institute, Oxfordshire, UK. Electronic address: silvia.corrochano@salud.madrid.org.

Publikováno v: Neurobiology of disease [Neurobiol Dis] 2024 Nov; Vol. 202, pp. 106708. Date of Electronic Publication: 2024 Oct 28.

Pridopidine Promotes Synaptogenesis and Reduces Spatial Memory Deficits in the Alzheimer's Disease APP/PS1 Mouse Model.

Autor: Estévez-Silva HM; Departamento de Ciencias Médicas Básicas, Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, Tenerife, Spain.; Department of Integrative Medical Biology, Umeå University, Umeå, Sweden., Cuesto G; Departamento de Ciencias Médicas Básicas, Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, Tenerife, Spain., Romero N; Departamento de Ciencias Médicas Básicas, Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, Tenerife, Spain., Brito-Armas JM; Unidad de Investigación, Hospital Universitario de Canarias, ITB-ULL/CIBERNED, Tenerife, Spain., Acevedo-Arozena A; Unidad de Investigación, Hospital Universitario de Canarias, ITB-ULL/CIBERNED, Tenerife, Spain., Acebes Á; Departamento de Ciencias Médicas Básicas, Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, Tenerife, Spain. aacebesv@ull.edu.es., Marcellino DJ; Department of Integrative Medical Biology, Umeå University, Umeå, Sweden. daniel.marcellino@umu.se.

Publikováno v: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2022 Sep; Vol. 19 (5), pp. 1566-1587. Date of Electronic Publication: 2022 Aug 02.

Generation and analysis of innovative genomically humanized knockin SOD1 , TARDBP (TDP-43), and FUS mouse models.

Autor: Devoy A; Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Price G; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., De Giorgio F; Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Bunton-Stasyshyn R; Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Thompson D; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Gasco S; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Allan A; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Codner GF; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Nair RR; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Tibbit C; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., McLeod R; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Ali Z; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Noda J; Research Unit, Hospital Universitario de Canarias; ITB-ULL and CIBERNED, 38320 La Laguna, Spain., Marrero-Gagliardi A; Research Unit, Hospital Universitario de Canarias; ITB-ULL and CIBERNED, 38320 La Laguna, Spain., Brito-Armas JM; Research Unit, Hospital Universitario de Canarias; ITB-ULL and CIBERNED, 38320 La Laguna, Spain., Williams C; Department of Integrative Medical Biology, Umeå University, 901 87, Umeå, Sweden., Öztürk MM; Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Simon M; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., O'Neill E; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Bryce-Smith S; Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Harrison J; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Atkins G; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Corrochano S; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Stewart M; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Gilthorpe JD; Department of Integrative Medical Biology, Umeå University, 901 87, Umeå, Sweden., Teboul L; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK., Acevedo-Arozena A; Research Unit, Hospital Universitario de Canarias; ITB-ULL and CIBERNED, 38320 La Laguna, Spain., Fisher EMC; Department of Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK., Cunningham TJ; UK MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD, UK.

Publikováno v: IScience [iScience] 2021 Nov 15; Vol. 24 (12), pp. 103463. Date of Electronic Publication: 2021 Nov 15 (Print Publication: 2021).

Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.

Autor: Fratta P; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK p.fratta@ucl.ac.uk aacevedo@ull.edu.es., Sivakumar P; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Humphrey J; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK.; UCL Genetics Institute, London, UK., Lo K; UCL Genetics Institute, London, UK., Ricketts T; MRC Mammalian Genetics Unit, Harwell, UK., Oliveira H; MRC Mammalian Genetics Unit, Harwell, UK., Brito-Armas JM; Unidad de Investigación, Hospital Universitario de Canarias, Fundación Canaria de Investigación Sanitaria and Instituto de Tecnologías Biomédicas (CIBICAN), La Laguna, Spain., Kalmar B; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Ule A; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Yu Y; UCL Centre for Advanced Biomedical Imaging, University College London, London, UK., Birsa N; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Bodo C; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Collins T; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Conicella AE; Graduate Program in Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA., Mejia Maza A; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Marrero-Gagliardi A; Unidad de Investigación, Hospital Universitario de Canarias, Fundación Canaria de Investigación Sanitaria and Instituto de Tecnologías Biomédicas (CIBICAN), La Laguna, Spain., Stewart M; MRC Mary Lyon Centre, Harwell, UK., Mianne J; MRC Mary Lyon Centre, Harwell, UK., Corrochano S; MRC Mammalian Genetics Unit, Harwell, UK., Emmett W; UCL Genetics Institute, London, UK., Codner G; MRC Mary Lyon Centre, Harwell, UK., Groves M; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Fukumura R; Mutagenesis and Genomics Team, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan., Gondo Y; Mutagenesis and Genomics Team, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan., Lythgoe M; UCL Centre for Advanced Biomedical Imaging, University College London, London, UK., Pauws E; UCL Institute of Child Health, London, UK., Peskett E; UCL Institute of Child Health, London, UK., Stanier P; UCL Institute of Child Health, London, UK., Teboul L; MRC Mary Lyon Centre, Harwell, UK., Hallegger M; UCL Institute of Neurology and Francis Crick Institute, London, UK., Calvo A; Rita Levi Montalcini Department of Neuroscience, University of Turin, Turin, Italy., Chiò A; Rita Levi Montalcini Department of Neuroscience, University of Turin, Turin, Italy., Isaacs AM; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK.; UK Dementia Research Institute at UCL, UCL Institute of Neurology, London, UK., Fawzi NL; Department of Molecular Pharmacology, Physiology & Biotechnology, Brown University, Providence, RI, USA., Wang E; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Housman DE; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Baralle F; International Center for Genomic Engineering and Biotechnology (ICGEB), Trieste, Italy., Greensmith L; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Buratti E; International Center for Genomic Engineering and Biotechnology (ICGEB), Trieste, Italy., Plagnol V; UCL Genetics Institute, London, UK., Fisher EM; UCL Institute of Neurology, and MRC Centre for Neuromuscular Disease, London, UK., Acevedo-Arozena A; MRC Mammalian Genetics Unit, Harwell, UK p.fratta@ucl.ac.uk aacevedo@ull.edu.es.; Unidad de Investigación, Hospital Universitario de Canarias, Fundación Canaria de Investigación Sanitaria and Instituto de Tecnologías Biomédicas (CIBICAN), La Laguna, Spain.

Publikováno v: The EMBO journal [EMBO J] 2018 Jun 01; Vol. 37 (11). Date of Electronic Publication: 2018 May 15.

Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits.

Autor: Hu, Yiying^1,2,3 (AUTHOR), Hruscha, Alexander¹ (AUTHOR), Pan, Chenchen^4,5 (AUTHOR), Schifferer, Martina^1,6 (AUTHOR), Schmidt, Michael K.⁷ (AUTHOR), Nuscher, Brigitte² (AUTHOR), Giera, Martin⁸ (AUTHOR), Kostidis, Sarantos⁸ (AUTHOR), Burhan, Özge¹ (AUTHOR), van Bebber, Frauke¹ (AUTHOR), Edbauer, Dieter^1,2,6 (AUTHOR), Arzberger, Thomas^7,9 (AUTHOR), Haass, Christian^1,2,6 (AUTHOR), Schmid, Bettina¹ (AUTHOR) bettina.schmid@dzne.de

Publikováno v: Molecular Neurodegeneration. 6/20/2024, Vol. 19 Issue 1, p1-23. 23p.