THE INFLAMMASOME DRIVES MICROVASCULAR IMPAIRMENT IN MOUSE MODELS OF INTRAVASCULAR HEMOLYSIS

Autor: Brito, PL, Azevedo, EMFG, Gushiken, LFS, Leonardo, FC, Costa, FF, Conran, N

Publikováno v: In Hematology, Transfusion and Cell Therapy October 2024 46 Supplement 4:S59-S59

PIEZO1 ACTIVATION INCREASES NEUTROPHIL ADHESIVE PROPERTIES IN SICKLE CELL ANEMIA

Autor: Leonardo, FC, Brito, PL, Egée, S, Nader, E, Connes, P, Saad, STO, Costa, FF, Conran, N

Publikováno v: In Hematology, Transfusion and Cell Therapy October 2023 45 Supplement 4:S46-S46

STANDARDIZATION OF THE MEASUREMENT AND IMAGING OF BLOOD PERFUSION OF THE SKIN MICROCIRCULATION IN TOWNES SICKLE CELL DISEASE MICE, USING THE LASER SPECKLE CONTRAST IMAGING TECHNIQUE

Autor: Gushiken, LFS, Azevedo, EMFG, Brito, PL, Leonardo, FC, Costa, FF, Conran, N

Publikováno v: In Hematology, Transfusion and Cell Therapy October 2023 45 Supplement 4:S43-S44

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Targeting P-selectin and interleukin-1β in mice with sickle cell disease: effects on vaso-occlusion, liver injury and organ iron deposition.

Autor: Gotardo ÉMF; Hematology Center, University of Campinas - UNICAMP, Campinas - São Paulo., Torres LS; Hematology Center, University of Campinas - UNICAMP, Campinas - São Paulo, Brazil; Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, New York, NY 10461., Zaidan BC; Federal University of Triângulo Mineiro, UFTM, Minas Gerais., Gushiken LFS; Hematology Center, University of Campinas - UNICAMP, Campinas - São Paulo., Brito PL; Hematology Center, University of Campinas - UNICAMP, Campinas - São Paulo., Leonardo FC; Hematology Center, University of Campinas - UNICAMP, Campinas - São Paulo., Pellizzon CH; São Paulo State University (UNESP), Institute of Biosciences, Botucatu., Millholland J; Novartis Precision Medicine, Cambridge, MA., Agoulnik S; Novartis Precision Medicine, Cambridge, MA, USA (former affiliation)., Kovarik J; Novartis Biomedical Research, Novartis Campus, CH-4056 Basel, Switzerland., Costa FF; Hematology Center, University of Campinas - UNICAMP, Campinas - São Paulo., Conran N; Hematology Center, University of Campinas - UNICAMP, Campinas - São Paulo. conran@unicamp.br.

Publikováno v: Haematologica [Haematologica] 2024 Nov 21. Date of Electronic Publication: 2024 Nov 21.