Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Britnie R. James"'
Autor:
Lyse A Norian, Timothy P Kresowik, Henry M Rosevear, Britnie R James, Timothy R Rosean, Andrew J Lightfoot, Tamara A Kucaba, Christopher Schwarz, Christine J Weydert, Michael D Henry, Thomas S Griffith
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31085 (2012)
Despite evidence that antitumor immunity can be protective against renal cell carcinoma (RCC), few patients respond objectively to immunotherapy and the disease is fatal once metastases develop. We asked to what extent combinatorial immunotherapy wit
Externí odkaz:
https://doaj.org/article/4fe1df20141b475bafe5b1f1f928699e
Autor:
Tamara A. Kucaba, Britnie R. James, Thomas S. Griffith, Andrew Wilber, Frances V. Sjaastad, Katherine A. Murphy, Hyunjoon Kim, Erik L. Brincks, Streamson C. Chua
Publikováno v:
The Journal of Immunology. 201:1837-1841
Various malignancies are reproducibly cured in mouse models, but most cancer immunotherapies show objective responses in a fraction of treated patients. One reason for this disconnect may be the use of young, lean mice lacking immune-altering comorbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81f756bbf9a1ab9f9910800c08fe769
https://doi.org/10.4049/jimmunol.1701738
https://doi.org/10.4049/jimmunol.1701738
Autor:
Thomas S. Griffith, Lin Niu, Tamara A. Kucaba, Britnie R. James, Katherine A. Murphy, Jayanth Panyam, Hyunjoon Kim, David M. Ferguson, Peter Larson
Publikováno v:
Biomaterials. 164:38-53
Cytotoxic T lymphocytes (CTLs) play a major role in cancer immunotherapy because of their ability to directly kill tumor cells and secrete tumor suppressive cytokines. Anticancer vaccines aim to provoke tumor-specific CTL responses, which require act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d22e8d9c751f5adc78532ed9c493412
https://doi.org/10.1016/j.biomaterials.2018.02.034
https://doi.org/10.1016/j.biomaterials.2018.02.034
Autor:
Britnie R. James, Veena Sangwan, Sulagna Banerjee, Thomas S. Griffith, Kathryn L. Schwertfeger, Katherine A. Murphy, Tamara A. Kucaba, Erik L. Brincks, Ashok K. Saluja
Publikováno v:
FEBS Journal. 282:4747-4765
Renal cell carcinoma (RCC) is resistant to traditional cancer therapies, and metastatic RCC (mRCC) is incurable. The shortcomings in current therapeutic options for patients with mRCC provide the rationale for the development of novel treatment proto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc2562cb1cd731e1965355617e7529a
https://doi.org/10.1111/febs.13532
https://doi.org/10.1111/febs.13532
Autor:
Britnie R. James, Thomas S. Griffith, Yue Guan, Andrew Wilber, Donald S. Torry, Katherine A. Murphy
Publikováno v:
Human Vaccines & Immunotherapeutics. 11:1612-1620
Clinical observations of spontaneous disease regression in some renal cell carcinoma (RCC) patients implicate a role for tumor immunity in controlling this disease. Puzzling, however, are findings that high levels of tumor infiltrating lymphocytes (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a90bbaada7e97d436d592fd0addb50
https://doi.org/10.1080/21645515.2015.1035849
https://doi.org/10.1080/21645515.2015.1035849
Autor:
Britnie R. James, Thomas S. Griffith, Deepa Rai, Tamara A. Kucaba, Vladimir P. Badovinac, Stephanie A. Condotta, Javier Cabrera-Perez, Sakeen W. Kashem, Erik L. Brincks
Publikováno v:
The Journal of Immunology. 194:1609-1620
Patients surviving the acute stages of sepsis develop compromised T cell immunity and increased susceptibility to infection. Little is known about the decreased CD4 T cell function after sepsis. We tracked the loss and recovery of endogenous Ag-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26e7c28944e49dbec09f3edb4e69fd84
https://doi.org/10.4049/jimmunol.1401711
https://doi.org/10.4049/jimmunol.1401711
Publikováno v:
Journal of Visualized Experiments.
Renal cell carcinoma (RCC) affects > 60,000 people in the United States annually, and ~ 30% of RCC patients have multiple metastases at the time of diagnosis. Metastatic RCC (mRCC) is incurable, with a median survival time of only 18 months. Immune-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb37bedd3ca61c5812a9136aacdf349
https://doi.org/10.3791/55080-v
https://doi.org/10.3791/55080-v
Autor:
Britnie R. James, Vaiva Vezys, Heungsup Sung, Kristin G. Anderson, Thomas S. Griffith, Daniel L. Barber, Lalit K. Beura, Katrin D. Mayer-Barber, Justin J. Taylor, Lindor Qunaj, David Masopust
Publikováno v:
Nature Protocols. 9:209-222
Characterization of the cellular participants in tissue immune responses is crucial to understanding infection, cancer, autoimmunity, allergy, graft rejection and other immunological processes. Previous reports indicate that leukocytes in lung vascul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567e728a0c8deadb1e5c617b79808142
https://doi.org/10.1038/nprot.2014.005
https://doi.org/10.1038/nprot.2014.005
Autor:
Kathy Robinson, Yue Guan, Shaheen Alanee, Christopher B. Chambers, Britnie R. James, Max Nutt, Donald S. Torry, Thomas S. Griffith, Andrew Wilber
Publikováno v:
Journal of Urology. 195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::757de47ea72dc98ff380270f365b89d2
https://doi.org/10.1016/j.juro.2016.02.2637
https://doi.org/10.1016/j.juro.2016.02.2637
Autor:
Britnie R. James, Thomas S. Griffith, Tamara A. Kucaba, Eric J. Askeland, Ann Tomanek-Chalkley, Lyse A. Norian
Publikováno v:
The Journal of Immunology. 189:1311-1321
Obesity is a mounting health concern in the United States and is associated with an increased risk for developing several cancers, including renal cell carcinoma (RCC). Despite this, little is known regarding the impact of obesity on antitumor immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6ab45f2d02727bcfae1f4a36f1449e
https://doi.org/10.4049/jimmunol.1100587
https://doi.org/10.4049/jimmunol.1100587