Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Britney E. Graham"'
Publikováno v:
Human Genomics, Vol 15, Iss 1, Pp 1-16 (2021)
Abstract The genetic basis of phenotypic variation across populations has not been well explained for most traits. Several factors may cause disparities, from variation in environments to divergent population genetic structure. We hypothesized that a
Externí odkaz:
https://doaj.org/article/188bba6c82a34b26af586ea930e6842c
Autor:
Joseph D Romano, Van Truong, Rachit Kumar, Mythreye Venkatesan, Britney E Graham, Yun Hao, Nick Matsumoto, Xi Li, Zhiping Wang, Marylyn D Ritchie, Li Shen, Jason H Moore
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e46777 (2024)
BackgroundAs global populations age and become susceptible to neurodegenerative illnesses, new therapies for Alzheimer disease (AD) are urgently needed. Existing data resources for drug discovery and repurposing fail to capture relationships central
Externí odkaz:
https://doaj.org/article/484c4a7497fd40b4bfb9252d73687d5c
Autor:
Joseph D Romano, Van Truong, Rachit Kumar, Mythreye Venkatesan, Britney E. Graham, Yun Hao, Nick Matsumoto, Xi Li, Zhiping Wang, Marylyn Ritchie, Li Shen, Jason H. Moore
BACKGROUND As global populations age and become susceptible to neurodegenerative illnesses, new therapies for Alzheimer’s Disease (AD) are urgently needed. Existing data resources for drug discovery and repurposing fail to capture heterogeneous bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f1ad3b203db8db5c8f5604cf2f2569b
https://doi.org/10.2196/preprints.46777
https://doi.org/10.2196/preprints.46777
Autor:
Johanna M Huusko, Minna K Karjalainen, Britney E Graham, Ge Zhang, Emily G Farrow, Neil A Miller, Bo Jacobsson, Haley R Eidem, Jeffrey C Murray, Bruce Bedell, Patrick Breheny, Noah W Brown, Frans L Bødker, Nadia K Litterman, Pan-Pan Jiang, Laura Russell, David A Hinds, Youna Hu, andMe Research Team, Antonis Rokas, Kari Teramo, Kaare Christensen, Scott M Williams, Mika Rämet, Stephen F Kingsmore, Kelli K Ryckman, Mikko Hallman, Louis J Muglia
Publikováno v:
PLoS Genetics, Vol 14, Iss 9, p e1007673 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1007394.].
Externí odkaz:
https://doaj.org/article/68534e5341a74437bcb568d25963de72
Autor:
Johanna M Huusko, Minna K Karjalainen, Britney E Graham, Ge Zhang, Emily G Farrow, Neil A Miller, Bo Jacobsson, Haley R Eidem, Jeffrey C Murray, Bruce Bedell, Patrick Breheny, Noah W Brown, Frans L Bødker, Nadia K Litterman, Pan-Pan Jiang, Laura Russell, David A Hinds, Youna Hu, andMe Research Team, Antonis Rokas, Kari Teramo, Kaare Christensen, Scott M Williams, Mika Rämet, Stephen F Kingsmore, Kelli K Ryckman, Mikko Hallman, Louis J Muglia
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007394 (2018)
Preterm birth is a leading cause of morbidity and mortality in infants. Genetic and environmental factors play a role in the susceptibility to preterm birth, but despite many investigations, the genetic basis for preterm birth remain largely unknown.
Externí odkaz:
https://doaj.org/article/7bdfe94f52ba4590af932ccfbe8a2c30
Publikováno v:
Human Genomics
Human Genomics, Vol 15, Iss 1, Pp 1-16 (2021)
Human Genomics, Vol 15, Iss 1, Pp 1-16 (2021)
The genetic basis of phenotypic variation across populations has not been well explained for most traits. Several factors may cause disparities, from variation in environments to divergent population genetic structure. We hypothesized that a populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d472b7f0feee28dc9340ec85c13da3
http://europepmc.org/articles/PMC8670062
http://europepmc.org/articles/PMC8670062
Autor:
Jason H. Moore, Scott M. Williams, Louis J. Muglia, Minjun Huang, Britney E. Graham, Christian Darabos
Methods to identify genes or pathways associated with complex diseases are often inadequate to elucidate most risk because they make implicit and oversimplified assumptions about underlying models of disease etiology. These can lead to incomplete or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee4dfde9abf6fe7440980b63bbc314c
https://europepmc.org/articles/PMC5696086/
https://europepmc.org/articles/PMC5696086/
Autor:
Scott M. Williams, Nuri Kodaman, Ge Zhang, Minjun Huang, Britney E. Graham, Jason H. Moore, Louis J. Muglia, Reed Harder
Publikováno v:
BioData Mining
Genetic studies of human diseases have identified many variants associated with pathogenesis and severity. However, most studies have used only statistical association to assess putative relationships to disease, and ignored other factors for evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19041109dce210d0d32c97ac9444b155
https://doi.org/10.1186/s13040-016-0091-7
https://doi.org/10.1186/s13040-016-0091-7
Publikováno v:
ECAL
In biological organisms, a single genotype may map to several phenotypes and vice-versa. This many-to-many relationship is believed to be a major drive of the phenotypic robustness and genotypic evolvability found in all life forms. Given the inheren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7c5bd5265de7a73bcb2bcb62e139b8e
https://doi.org/10.7551/978-0-262-31709-2-ch051
https://doi.org/10.7551/978-0-262-31709-2-ch051
Publikováno v:
GECCO (Companion)
In biological organisms, a single genotype may map to several phenotypes and vice-versa. This many-to-many relationship is believed to be a major drive of the phenotypic robustness and genotypic evolvability found in all life forms. Given the inheren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e58190cbdcfe1ed2221154328cd98987
https://doi.org/10.1145/2464576.2480789
https://doi.org/10.1145/2464576.2480789