Thioalbamide inhibits FoF1-ATPase in breast cancer cells and reduces tumor proliferation and invasiveness in breast cancer in vivo models

Autor: Frattaruolo, L., Malivindi, R., Brindisi, M., Rago, V., Curcio, R., Lauria, G., Fiorillo, M., Dolce, V., Truman, A.W., Cappello, A.R.

Publikováno v: In Molecular Metabolism February 2023 68

Tackling triple negative breast cancer with HDAC inhibitors: 6 is the isoform!

Autor: Guadagni A; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy., Barone S; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy., Alfano AI; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy., Pelliccia S; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy., Bello I; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy., Panza E; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy., Summa V; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy., Brindisi M; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131, Naples, Italy. Electronic address: margherita.brindisi@unina.it.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 Dec 05; Vol. 279, pp. 116884. Date of Electronic Publication: 2024 Sep 16.

A First-in-Class Pyrazole-isoxazole Enhanced Antifungal Activity of Voriconazole: Synergy Studies in an Azole-Resistant Candida albicans Strain, Computational Investigation and in Vivo Validation in a Galleria mellonella Fungal Infection Model.

Autor: Pelliccia S; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy., Russomanno P; Magnetic Resonance Centre (CERM), Consorzio Interuniversitario Risonanze Magnetiche di Metallo Proteine (CIRMMP) and Department of Chemistry 'Ugo Schiff', University of Florence, Via L. Sacconi 6, Sesto Fiorentino 50019, Italy., Barone S; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy., Mateu B; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy., Alfano AI; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy., Miranda M; Department of Pharmaceutical and Cell Biological Chemistry, Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany., Coretti L; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy., Lembo F; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy., Piccolo M; BioChemLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy., Irace C; BioChemLab, Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy., Friggeri L; Department of Cell and Development Biology, U4225 Medical Research Building III, 465 21st Avenue South Room 4160 MRB III Nashville, Tennessee 37232, United States., Hargrove TY; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States., Curtis A; Department of Biology, Maynooth University, W23 F2H6 Maynooth, Co. Kildare, Ireland., Lepesheva GI; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States., Kavanagh K; Department of Biology, Maynooth University, W23 F2H6 Maynooth, Co. Kildare, Ireland., Buommino E; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy., Brindisi M; Department of Pharmacy (DoE 2023-2027), University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Aug 22; Vol. 67 (16), pp. 14256-14276. Date of Electronic Publication: 2024 Aug 08.

New insights into cholesterol-mediated ERRα activation in breast cancer progression and pro-tumoral microenvironment orchestration.

Autor: Brindisi M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.; Cell Adhesion Unit, Vita-Salute San Raffaele University, Milan, Italy., Frattaruolo L; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy., Fiorillo M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.; Translational Medicine, School of Science, Engineering and the Environment (SEE), University of Salford, Greater Manchester, UK., Dolce V; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy., Sotgia F; Translational Medicine, School of Science, Engineering and the Environment (SEE), University of Salford, Greater Manchester, UK., Lisanti MP; Translational Medicine, School of Science, Engineering and the Environment (SEE), University of Salford, Greater Manchester, UK., Cappello AR; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.

Publikováno v: The FEBS journal [FEBS J] 2023 Mar; Vol. 290 (6), pp. 1481-1501. Date of Electronic Publication: 2022 Oct 26.

Potential influence of Type A personality on plasma C-reactive protein levels in people with diabetes

Autor: Chauvet-Gélinier, J.-C., Trojak, B., Lemogne, C., Aho-Glélé, L.-S., Brindisi, M.-C., Bouillet, B., Ponavoy, E., Meille, V., Simoneau, I., Chahraoui, K., Vaillant, G., Petit, J.-M., Consoli, S.M., Bonin, B., Vergès, B.

Publikováno v: In Diabetes and Metabolism April 2016 42(2):88-95