Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Brinda Vijaykumar"'
Autor:
Christine McInnis, Lakshmi Srinivasan, Anthony J Coyle, Shilpa Bhatia, Glenn J Hanna, Ann Marie Egloff, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Daniel C Pregibon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background High-risk human papillomavirus (HPV) is a primary cause of an increasing number of oropharyngeal squamous cell carcinomas (OPSCCs). The viral etiology of these cancers provides the opportunity for antigen-directed therapies that are restri
Externí odkaz:
https://doaj.org/article/8563618d2440465aa2a5fd3a1eb10376
Autor:
Ricardo Grieshaber-Bouyer, Felix A. Radtke, Pierre Cunin, Giuseppina Stifano, Anaïs Levescot, Brinda Vijaykumar, Nathan Nelson-Maney, Rachel B. Blaustein, Paul A. Monach, Peter A. Nigrovic, ImmGen Consortium
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Differentiating neutrophil functional states is difficult. Here the authors show, using single cell RNA-sequencing and trajectory analyses, that mouse neutrophils can be presented as a transcriptome continuum rather than discrete subsets, but are aff
Externí odkaz:
https://doaj.org/article/a869daba818542d3a779eb3e37bafc52
Autor:
Shilpa Bhatia, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Charles Quinn, Sean Donnelly, Ravindra Uppaluri, Ann Marie Egloff, Daniel Pregibon, Lakshmi Srinivasan, Anthony Coyle, Glenn Hanna, Christine McInnis
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Christine McInnis, Shilpa Bhatia, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles Quinn, Sean Donnelly, Ravindra Uppaluri, Ann Marie Egloff, Daniel Pregibon, Lakshmi Srinivasan, Anthony Coyle, Glenn Hanna
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Diane Mathis, Christophe Benoist, Elijah Willie, Evgeny Kiner, Kaitavjeet Chowdhary, Alexandra Schnell, Sara Mostafavi, Graham LeGros, Hugo Schmutz, Pratiksha I. Thakore, Brinda Vijaykumar, Jodie Chandler
Publikováno v:
PMC
CD4 effector lymphocytes (T ) are traditionally classified by the cytokines they produce. To determine the states that T cells actually adopt in frontline tissues in vivo, we applied single-cell transcriptome and chromatin analyses to colonic T cells
Autor:
Christophe Benoist, Kaitavjeet Chowdhary, Elke Mühlberger, Liang Yang, Hyung Suk Oh, Yangyang Zhu, Juliette Leon, Lael M. Yonker, Adam J. Hume, Silvia Galván-Peña, David M. Knipe, Daniel A Michelson, Brinda Vijaykumar, Felicia Chen, Judith Olejnik
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance By modeling in vitro the cross-talk between epithelial and immune cells, this work provides possible origins for the profound inflammatory perturbations that are a hallmark of COVID-19, and the relative protection of children from severe
Autor:
Evgeny Kiner, Elijah Willie, Brinda Vijaykumar, Diane Mathis, Christophe Benoist, Jodie Chandler, Graham LeGros, Hugo Schmutz, Alexandra Schnell, Sara Mostafavi, Pratiksha I. Thakore, Kaitavjeet Chowdhary
Publikováno v:
Nature Immunology. 22:666-668
In the version of this article initially published, in the second paragraph of Results section “Teff phenotypes over time,” “Tcra and Tcra genes” should have read “Tcra and Tcrb genes.” In numbered paragragh 3 of “New Teff populations,
Autor:
Felix A Radtke, Peter A. Nigrovic, Nathan Nelson-Maney, Paul A. Monach, Pierre Cunin, Anaïs Levescot, Giuseppina Stifano, Brinda Vijaykumar, Ricardo Grieshaber-Bouyer, Rachel B Blaustein
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Neutrophils are implicated in multiple homeostatic and pathological processes, but whether functional diversity requires discrete neutrophil subsets is not known. Here, we apply single-cell RNA sequencing to neutrophils from normal and inflamed mouse
Autor:
Xu G. Yu, Diane Mathis, Silvia Galván-Peña, Daniel P Worrall, Daniel A Michelson, Juliette Leon, Alicja Piechocka-Trocha, Bruce D. Walker, Christophe Benoist, Kaitavjeet Chowdhary, Jonathan Z. Li, Musie Ghebremichael, Felicia Chen, Liang Yang, Kathryn E Hall, Zachary Manickas-Hill, Brinda Vijaykumar, Angela Magnuson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
bioRxiv
bioRxiv
Significance Regulatory T cells (Tregs) are responsible for restraining excessive inflammation, a hallmark of COVID-19. We identified a striking phenotype in Tregs from patients with severe disease, as well as an interesting role for interleukin (IL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ddf4f9d210a708c6c959f65a15d242
https://doi.org/10.1101/2020.12.11.416180
https://doi.org/10.1101/2020.12.11.416180
Autor:
Christophe Benoist, Meenakshi Rao, Milena Rozenberg, Yiqing Yan, Shalev Itzkovitz, Diane Mathis, Munir Mosaheb, Kelly McGovern, Daniella Rastelli, Omar M. Yaghi, Brinda Vijaykumar, Tiphaine Voisin, Deepshika Ramanan, Isaac M. Chiu
Publikováno v:
Immunity. 54(3)
Summary The immune and enteric nervous (ENS) systems monitor the frontier with commensal and pathogenic microbes in the colon. We investigated whether FoxP3+ regulatory T (Treg) cells functionally interact with the ENS. Indeed, microbe-responsive ROR