Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Brinda Chandar"'
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Improper use of antibiotics has led to a great concern in the development of pathogenic microbial resistance. New Delhi metallo-β-lactamase 1 (NDM-1) producing bacteria are resistant to most of the β-lactam antibiotics, and so far, no new compounds
Externí odkaz:
https://doaj.org/article/6351a4f3c70a4273995ceaedd7bb9a53
Autor:
Inga V. Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S. Walker, Brian Squadroni, Carl J. Balibar, Nihar Kinarivala, Lisa C. Standke, Henning U. Voss, Derek S. Tan, Valentin V. Rybenkov, Helen I. Zgurskaya
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Gram-negative bacteria are notoriously more resistant to antibiotics than Gram-positive bacteria, primarily due to the presence of the outer membrane and a plethora of active efflux pumps. However, the potency of antibiotics also varies dramatically
Autor:
Ziwei Hu, Inga V. Leus, Brinda Chandar, Bradley S. Sherborne, Quentin P. Avila, Valentin V. Rybenkov, Helen I. Zgurskaya, Adam S. Duerfeldt
Publikováno v:
Journal of medicinal chemistry. 65(20)
The clinical success of linezolid for treating Gram-positive infections paired with the high conservation of bacterial ribosomes predicts that if oxazolidinones were engineered to accumulate in Gram-negative bacteria, then this pharmacological class
Autor:
Attilio Vittorio Vargiu, Giuliano Malloci, Brinda Chandar, Paolo Ruggerone, Helen I. Zgurskaya
Publikováno v:
Curr Opin Microbiol
All mechanisms of clinical antibiotic resistance benefit from activities of polyspecific efflux pumps acting to reduce intracellular accumulation of toxins and antibiotics. In Gram-negative bacteria, the major polyspecific efflux transporters belong
Autor:
Haimanti Bhattacharya, Bipasa Kar, Brinda Chandar, Suman Smruti Rachana, Debdutta Bhattacharya
Publikováno v:
Journal of Herbal Medicine. 32:100502
Worldwide rapid spread of multi drug resistance among the community as well as healthcare associated bacterial infections has impaired the current antimicrobial therapy, warranting the search for other alternatives. The current study aimed to find th
Publikováno v:
Indian Journal of Medical Research, Vol 147, Iss 1, Pp 97-101 (2018)
The Indian Journal of Medical Research
The Indian Journal of Medical Research
Background & objectives: New Delhi metallo-β-lactamase 1 (NDM-1) cleaves the beta-lactam ring, and confers bacterial resistance against most of the beta-lactam antibiotics, except tigecycline and colistin. Among these two antibiotics, colistin is co
Autor:
Brinda Chandar, Debdutta Bhattacharya
Publikováno v:
Current topics in medicinal chemistry. 19(10)
A rapid growth in drug resistance has brought options for treating antimicrobial resistance to a halt. Bacteria have evolved to accumulate a multitude of genes that encode resistance for a single drug within a single cell. Alternations of drug transp
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 8 (2017)
Frontiers in Microbiology, Vol 8 (2017)
Improper use of antibiotics has led to a great concern in the development of pathogenic microbial resistance. New Delhi metallo-β-lactamase 1 (NDM-1) producing bacteria are resistant to most of the β-lactam antibiotics, and so far, no new compounds
Autor:
Brinda Chandar, Ramasamy, M. K.
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9aac637a2906217f7b743c9a27cec70c
http://www.scopus.com/inward/record.url?eid=2-s2.0-84978162127&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-84978162127&partnerID=MN8TOARS