Active Mediated Transport of Chloramphenicol and Thiamphenicol in a Calu-3 Lung Epithelial Cell Model

Autor: Nurbaeti, Siti N., Olivier, Jean-Christophe, Adier, Christophe, Marchand, Sandrine, Couet, William, Brillault, Julien

Publikováno v: In Journal of Pharmaceutical Sciences April 2018 107(4):1178-1184

Control of the Lung Residence Time of Highly Permeable Molecules after Nebulization: Example of the Fluoroquinolones

Autor: Brillault, Julien, Tewes, Frederic

Publikováno v: Pharmaceutics
Pharmaceutics, MDPI, 2020, 12 (4), pp.E387. ⟨10.3390/pharmaceutics12040387⟩

International audience; Pulmonary drug delivery is a promising strategy to treat lung infectious disease as it allows for a high local drug concentration and low systemic side effects. This is particularly true for low-permeability drugs, such as tob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::433764c2258b74f9b47bfc83c40ef265
https://www.hal.inserm.fr/inserm-02558855

Inhalable microparticles loaded with a fluoroquinolone/metal cation complex for the treatment of respiratory diseases

Autor: Tewes, Frédéric, brillault, julien, Smyth, Hugh D.C.

Publikováno v: France, Patent n° : WO2018104759A1. 2018

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e33e5f86e69fabee46238fd6470ddf0e
https://hal.archives-ouvertes.fr/hal-02485017

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Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models

Autor: Lundquist, Stefan, Rentfel, M., brillault, julien, Fenart, Laurence, Cecchelli, Romeo, Dehouck, Marie-Pierre

Publikováno v: Pharmaceutical Research
Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2002, 19 (7), p. 976-981
Pharmacological Research
Pharmacological Research, Elsevier, 2002, ⟨10.1023/a:1016462205267⟩

International audience; Purpose. Studies were conducted to evaluate whether the use of an in vitro model of the blood-brain barrier (BBB) resulted in more accurate predictions of the in vivo transport of compounds compared to the use of a human intes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dcc04875015e3a657ba921187d7ef702
https://hal-univ-artois.archives-ouvertes.fr/hal-00537269