Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane's antioxidant response element activation, even as they suppress Nrf2 protein accumulation.

Autor: Bauman BM; Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, United States., Jeong C; Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, United States., Savage M; Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, United States., Briker AL; Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, United States., Janigian NG; Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, United States., Nguyen LL; Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, United States., Kemmerer ZA; Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, United States., Eggler AL; Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, United States. Electronic address: aimee.eggler@villanova.edu.

Publikováno v: Free radical biology & medicine [Free Radic Biol Med] 2018 Aug 20; Vol. 124, pp. 532-540. Date of Electronic Publication: 2018 Jun 30.