Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Brijesh Kumar Singh"'
Autor:
Reddemma Sandireddy, Suganya Sakthivel, Priyanka Gupta, Jatin Behari, Madhulika Tripathi, Brijesh Kumar Singh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is the most common liver disorder worldwide, with an estimated global prevalence of more than 31%. Metabolic dysfunction-
Externí odkaz:
https://doaj.org/article/2743a4cc294e4557961a319afae5bacc
Autor:
Jin Zhou, Jeremy Pang, Madhulika Tripathi, Jia Pei Ho, Anissa Anindya Widjaja, Shamini Guna Shekeran, Stuart Alexander Cook, Ayako Suzuki, Anna Mae Diehl, Enrico Petretto, Brijesh Kumar Singh, Paul Michael Yen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Spermidine, a polyamine reported to extend lifespan and reduce the risk of age-related diseases, serves as a substrate for the post-translational modification hypusination. Here the authors report that EIF5A hypusination, which regulates mitochondria
Externí odkaz:
https://doaj.org/article/27de688eb5a24929b14771a4cd8acfce
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/cfa87056e2ec43acba79aa394337ffe2
Autor:
Sachchida Nand Rai, Payal Singh, Ritu Varshney, Vivek K Chaturvedi, Emanuel Vamanu, M P Singh, Brijesh Kumar Singh
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 9, Pp 1730-1739 (2021)
Parkinson’s disease (PD) is one of the most debilitating brain diseases. Despite the availability of symptomatic treatments, response towards the health of PD patients remains scarce. To fulfil the medical needs of the PD patients, an efficacious a
Externí odkaz:
https://doaj.org/article/f3c4336de57040c59ca554b2a1708dfe
Autor:
Eveline Bruinstroop, Jin Zhou, Madhulika Tripathi, Winifred W. Yau, Anita Boelen, Brijesh Kumar Singh, Paul M. Yen
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101266- (2021)
Objective: Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from hepatosteatosis to progressive nonalcoholic steatohepatitis that can lead to cirrhosis. Humans with low levels of prohormone thyroxine (T4) have a higher incidence
Externí odkaz:
https://doaj.org/article/d879531f2fef46d28ca34500556eedee
Autor:
Winifred W. Yau, Kiraely Adam Wong, Jin Zhou, Nivetha Kanakaram Thimmukonda, Yajun Wu, Boon-Huat Bay, Brijesh Kumar Singh, Paul Michael Yen
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102434- (2021)
Summary: Autophagy plays an important role in lipid breakdown, mitochondrial turnover, and mitochondrial function during brown adipose tissue (BAT) activation by thyroid hormone, but its role in BAT during adaptive thermogenesis remains controversial
Externí odkaz:
https://doaj.org/article/28ac87c58a7c403097bab2ff00935f85
Autor:
Bhupender Kumar, Mukesh Choudhary, Pardeep Kumar, Krishan Kumar, Sonu Kumar, Brijesh Kumar Singh, Chayanika Lahkar, Meenakshi, Pushpendra Kumar, Zahoor Ahmed Dar, Rakesh Devlash, Karambir Singh Hooda, Satish Kumar Guleria, Sujay Rakshit
Publikováno v:
Genes, Vol 13, Iss 4, p 618 (2022)
Maize is an important cereal crop in the world for feed, food, fodder, and raw materials of industries. Turcicum leaf blight (TLB) is a major foliar disease that can cause more than 50% yield losses in maize. Considering this, the molecular diversity
Externí odkaz:
https://doaj.org/article/6c76908ac4904c2991e1a006e83b022a
Autor:
Bhupender Kumar, Sujay Rakshit, Sonu Kumar, Brijesh Kumar Singh, Chayanika Lahkar, Abhishek Kumar Jha, Krishan Kumar, Pardeep Kumar, Mukesh Choudhary, Shyam Bir Singh, John J. Amalraj, Bhukya Prakash, Rajesh Khulbe, Mehar Chand Kamboj, Neeraja N. Chirravuri, Firoz Hossain
Publikováno v:
Plants, Vol 11, Iss 6, p 799 (2022)
Several maize breeding programs in India have developed numerous inbred lines but the lines have not been characterized using high-density molecular markers. Here, we studied the molecular diversity, population structure, and linkage disequilibrium (
Externí odkaz:
https://doaj.org/article/be771f79ba1d4e29ae0a199333dd2814
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100064- (2020)
Summary: Previously developed senescent primary fibroblast models have limited relevance to study age-related changes in metabolically active tissues such as the liver. Here, we describe a protocol to generate senescent cells from the mouse hepatic c
Externí odkaz:
https://doaj.org/article/e6ee686542c84003b84e890e1d30daf6
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Externí odkaz:
https://doaj.org/article/e54c4bc02f294f47b5fc5d47e4b877fb