Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Brijesh K. Garg"'
Autor:
Anish Deshpande, Remitha M. Vinayakamoorthy, Brijesh K. Garg, Jaya Prakash Thummapudi, Gauri Oza, Ketaki Adhikari, Aayush Agarwal, Parnika Dalvi, Swetha Iyer, Sarulatha Thulasi Raman, Vijay Ramesh, Akshitha Rameshbabu, Alexandra Rezvaya, Sneha Sukumaran, Sweta Swaminathan, Bhargav Tilak, Zhiyuan Wang, Phu V. Tran, Ralph H. Loring
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 470 (2020)
Alpha7 nicotinic acetylcholine receptors (α7nAChRs) are interesting not only because of their physiological effects, but because this receptor requires chaperones to traffic to cell surfaces (measured by alpha-bungarotoxin [αBGT] binding). While kn
Externí odkaz:
https://doaj.org/article/f567f2bd8446406ebedf129b5720431b
Autor:
Brijesh K Garg, Ralph H Loring
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214942 (2019)
α7 Nicotinic acetylcholine receptors (nAChRs) reportedly reduce inflammation by blocking effects of the important pro-inflammatory transcription factor, nuclear factor kappa-light chain-enhancer of B cells (NFκB). The α7 nAChR partial agonist GTS-
Externí odkaz:
https://doaj.org/article/746e8632d8294813afabd73aff08eee6
Autor:
Sarulatha Thulasi Raman, Zhiyuan Wang, Vijay Ramesh, Akshitha Rameshbabu, Aayush Agarwal, Sneha Sukumaran, Gauri Oza, Jaya Prakash Thummapudi, Phu V. Tran, Alexandra Rezvaya, Remitha M. Vinayakamoorthy, Ketaki Adhikari, Sweta Swaminathan, Bhargav Tilak, Brijesh K. Garg, Anish Deshpande, Ralph H. Loring, Swetha Iyer, Parnika Dalvi
Publikováno v:
Biomolecules
Volume 10
Issue 3
Biomolecules, Vol 10, Iss 3, p 470 (2020)
Volume 10
Issue 3
Biomolecules, Vol 10, Iss 3, p 470 (2020)
Alpha7 nicotinic acetylcholine receptors (&alpha
7nAChRs) are interesting not only because of their physiological effects, but because this receptor requires chaperones to traffic to cell surfaces (measured by alpha-bungarotoxin [&alpha
BGT
7nAChRs) are interesting not only because of their physiological effects, but because this receptor requires chaperones to traffic to cell surfaces (measured by alpha-bungarotoxin [&alpha
BGT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47d13d51f97c3bc1252bf3135b2215c
Autor:
Brijesh K. Garg, Ralph H. Loring
Publikováno v:
Journal of Histochemistry & Cytochemistry. 65:499-512
Alpha7 nicotinic acetylcholine receptors (α7 nAChRs) are important drug targets in neurological disorders and inflammation, making their detection and localization by validated antibodies highly desirable. However, tests in knockout animals raised q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbec5b2cc8730a8ebf0c48c28652211
https://doi.org/10.1369/0022155417725304
https://doi.org/10.1369/0022155417725304
Publikováno v:
Curr Protoc Protein Sci
Affinity purification followed by mass spectrometry has become the technique of choice to identify binding partners in biochemical complexes isolated from a physiologic cellular context. In this report we detail our protocol for tandem affinity purif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f8fa3efb4ed85699d446d3a03652fc
https://pubmed.ncbi.nlm.nih.gov/30706993
https://pubmed.ncbi.nlm.nih.gov/30706993
Autor:
Priya S. Chockalingam, Stephen Fait, Hans Boehringer, Zhiwei Zhou, Roy B. Chung, Brijesh K. Garg
Publikováno v:
International Immunopharmacology. 83:106526
Hereditary Angioedema (HAE) is a rare, autosomal dominant disease caused by mutations in SERPING1 gene leading to dysfunction/deficiency of C1-esterase inhibitor (C1-INH) protein and subsequent dysregulation of the contact system and bradykinin overp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b00b5b8e0b186bab2edc497445e3e3
https://doi.org/10.1016/j.intimp.2020.106526
https://doi.org/10.1016/j.intimp.2020.106526
Publikováno v:
International Immunopharmacology. 81:106348
Hereditary angioedema (HAE) types I and II are characterized by functional C1 inhibitor (fC1-INH) deficiency which results in bradykinin overproduction. Sensitive, specific and robust methods to quantitate fC1-INH in human samples are required for di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43735d303f976bcd357c4964c4421053
https://doi.org/10.1016/j.intimp.2020.106348
https://doi.org/10.1016/j.intimp.2020.106348
Autor:
Guillaume Adelmant, Jarrod A. Marto, Bijan Sobhian, Pamela A. Silver, Brijesh K. Garg, Jean Bernard Lazaro, Yi Zhang, Anne S. Calkins, Yoshihiro Nakatani, Alex Miron, Manor Askenazi, Joseph D. Card, J. Dirk Iglehart
Publikováno v:
Molecular & Cellular Proteomics. 11:411-421
The Ku heterodimer plays an essential role in non-homologous end-joining and other cellular processes including transcription, telomere maintenance and apoptosis. While the function of Ku is regulated through its association with other proteins and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69b5aee6df4dfb51f4dcec99fbdbb94
https://doi.org/10.1074/mcp.m111.013581
https://doi.org/10.1074/mcp.m111.013581
Autor:
Ralph H. Loring, Brijesh K. Garg
Publikováno v:
The FASEB Journal. 29
α7 nicotinic receptors (α7 AChRs) reportedly play anti-inflammatory roles in innate immune function, in part by blocking the transcription factor NFkB. We tested whether heterologously expressed α7...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3010865927c949c170edcd5eb1e652ee
https://doi.org/10.1096/fasebj.29.1_supplement.lb510
https://doi.org/10.1096/fasebj.29.1_supplement.lb510
Publikováno v:
The FASEB Journal. 27
TNF (Tumor necrosis factor alpha) and IL-6 (Interleukin 6) are cytokines with important inflammation and cancer roles that exhibit different interactions depending on cell context, e.g. TNF sometim...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff01abb839d8f75d2aff8a530bef9e2a
https://doi.org/10.1096/fasebj.27.1_supplement.lb552
https://doi.org/10.1096/fasebj.27.1_supplement.lb552