Výsledky vyhledávání - "Brigitte Voutsinos-Porche"

Akademický článek

Temporal patterns of the cerebral inflammatory response in the rat lithium–pilocarpine model of temporal lobe epilepsy

Autor: Brigitte Voutsinos-Porche, Estelle Koning, Hervé Kaplan, Arielle Ferrandon, Moncef Guenounou, Astrid Nehlig, Jacques Motte

Publikováno v: Neurobiology of Disease, Vol 17, Iss 3, Pp 385-402 (2004)

To better understand the role of inflammatory responses in temporal lobe epilepsy, we characterized Interleukin1-β (IL1-β), Nuclear Factor-κB (NF-κB), and Cyclooxygenase-2 (COX-2) expression together with neurodegeneration in the rat lithium–pi

Externí odkaz: https://doaj.org/article/4046a5c0bf1448198e3acc736dad3e33

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EAAC1 Glutamate Transporter Expression in the Rat Lithium-Pilocarpine Model of Temporal Lobe Epilepsy

Autor: Astrid Nehlig, Estelle Koning, Arielle Ferrandon, Jacques Motte, Hervé Kaplan, Yann Clément, Brigitte Voutsinos-Porche

Publikováno v: Journal of Cerebral Blood Flow & Metabolism. 26:1419-1430

Glutamate excitotoxicity has been involved in the pathophysiology of epilepsy. Normal functioning of glutamate transporters clears the synaptically released glutamate to prevent excitotoxic neuronal death. Using densitometric immunohistochemical anal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8ae5532a5d041edd22845da6a53b72
https://doi.org/10.1038/sj.jcbfm.9600295

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Role of astrocytes in coupling synaptic activity to glucose utilization

Autor: Brigitte Voutsinos-Porche, Pierre J. Magistretti, Kohichi Tanaka, Luc Pellerin, Jean-Yves Chatton, Jean-François Brunet, Gilles Bonvento

Publikováno v: The tripartite synapse : glia in synaptic transmission

Recently, in vitro evidence has suggested that astrocytes might play an important role in coupling neuronal activity to glucose utilization. The mechanism proposed to explain such coupling involves the uptake of glutamate by astrocytes via specific t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b7e01d6a5e17b618ee928046981070f
https://doi.org/10.1016/s0531-5131(02)00186-3

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Adrenomedullin expression and regulation in human glioblastoma, cultured human glioblastoma cell lines and pilocytic astrocytoma

Autor: Brigitte Voutsinos-Porche, Dominique Figarella-Branger, Dominique Intagliata, Caroline Berenguer, Philippe Metellus, Olivier Chinot, Anderson Loundou, Nadège Dussault, Françoise Boudouresque, Pierre-Marie Martin, Carole Colin, Frédéric Fina, L'Houcine Ouafik, Isabelle Nanni-Metellus

Publikováno v: European Journal of Cancer
European Journal of Cancer, Elsevier, 2011, 47 (11), pp.1727-1735. ⟨10.1016/j.ejca.2011.02.021⟩

Clinical and experimental studies suggest that angiogenesis is a prerequisite for solid tumour growth. Glioblastoma (GBM) and pilocytic astrocytoma (PA), both angiogenic tumours display strong contrast enhancement associated with peripheral oedema in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9fc1a3a1b10980cf1fc3bef053f302
https://pubmed.ncbi.nlm.nih.gov/21458987

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High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas

Autor: Olivier Chinot, Dominique Intagliata, Frédéric Fina, Dominique Figarella-Branger, Janko Kos, L'Houcine Ouafik, Tamara T. Lah, Philippe Metellus, Corinne Bouvier, Anderson Loundou, N. Baeza, Brigitte Voutsinos-Porche, Carole Colin, Christine Delfino, Pierre-Marie Martin, Isabelle Nanni

Publikováno v: Acta Neuropathologica
Acta Neuropathologica, Springer Verlag, 2009, 118 (6), pp.745-754. ⟨10.1007/s00401-009-0592-2⟩

In contrast to pilocytic astrocytomas (WHO grade I gliomas) that are circumscribed and cured by surgical resection, invasion is a hallmark of grades II-IV gliomas. Proteases play a major role in the invasion process and correlations between glioma gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8da679d3a96242c23b6abccbe640d6
https://hal-amu.archives-ouvertes.fr/hal-01848025

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Pilocytic astrocytoma of the optic pathway: a tumour deriving from radial glia cells with a specific gene signature

Autor: Dominique Intagliata, Brigitte Voutsinos-Porche, Aurélie Tchoghandjian, Ikbale El Ayachi, Caroline Fraslon-Vanhulle, Frédéric Fina, Dominique Figarella-Branger, L'Houcine Ouafik, Carla Fernandez, Didier Scavarda, Marie-Dominique Piercecchi-Marti, Carole Colin

Publikováno v: Brain-A Journal of Neurology
Brain-A Journal of Neurology, 2009, 132 (6), pp.1523-1535. ⟨10.1093/brain/awp048⟩
Brain-A Journal of Neurology, Oxford University Press (OUP), 2009, 132 (6), pp.1523-1535. ⟨10.1093/brain/awp048⟩

International audience; Pilocytic astrocytomas are WHO grade I gliomas that occur predominantly in childhood. They share features of both astroglial and oligodendroglial lineages. These tumours affect preferentially the cerebellum (benign clinical co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f64e7f770866d9f31b2525672c3e9c3
https://hal-amu.archives-ouvertes.fr/hal-01848070

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Molecular characterization of the response to chemotherapy in conventional osteosarcomas: predictive value of HSD17B10 and IFITM2

Autor: Brigitte Voutsinos-Porche, Catherine Charbonnel, Pascal Jézéquel, Sébastien Salas, Dominique Figarella-Branger, Wilfried Gouraud, Corinne Bouvier, Jean-Claude Gentet, Jean-Laurent Deville, Florence Duffaud, Frédéric Chibon, Anne Brouchet, Catherine Bartoli, Loïc Campion

Publikováno v: International journal of cancer. 125(4)

The therapy regimen of high-grade osteosarcoma includes chemotherapy followed by surgical resection and postoperative chemotherapy. The degree of necrosis following definitive surgery remains the only reliable prognostic factor and is used to guide t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8325c862b584b30c9974c2debe405014
https://pubmed.ncbi.nlm.nih.gov/19449377

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The Astrocyte—Neuron Lactate Shuttle: A Debated but still Valuable Hypothesis for Brain Imaging

Autor: Anne-Sophie Hérard, Gilles Bonvento, Brigitte Voutsinos-Porche

Publikováno v: Journal of Cerebral Blood Flow and Metabolism
Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2005, 25 (10), pp.1394-1399. ⟨10.1038/sj.jcbfm.9600127⟩
Journal of Cerebral Blood Flow and Metabolism, 2005, 25 (10), pp.1394-1399. ⟨10.1038/sj.jcbfm.9600127⟩

International audience; Ten years ago, Luc Pellerin and Pierre Magistretti in Lausanne (Switzerland) made the first observation that glutamate stimulates, in a dose-dependent manner, glucose uptake into cultured astrocytes. The second observation was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e06909fdc9c2d98d8049ca69f8528c
https://hal.archives-ouvertes.fr/hal-02155604

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Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex

Autor: Brigitte Voutsinos-Porche, Kohichi Tanaka, Pierre J. Magistretti, Gilles Bonvento, Egbert Welker, Luc Pellerin, Jean-Yves Chatton, Pascal Steiner

Publikováno v: Neuron. 37(2)

Neuron-glia interactions are essential for synaptic function, and glial glutamate (re)uptake plays a key role at glutamatergic synapses. In knockout mice, for either glial glutamate transporters, GLAST or GLT-1, a classical metabolic response to syna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15595a71f4d7105fc3ce964743a05914
https://pubmed.ncbi.nlm.nih.gov/12546812

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