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pro vyhledávání: '"Brigitte R. Gaume"'
Autor:
Gerald W. Dorn, Stephen B. Liggett, Brigitte R. Gaume, Natalia Petrashevskaya, A B S Kathryn Mihlbachler
Publikováno v:
Clinical and Translational Science. 1:221-227
Cardiomyopathic effects of beta-adrenergic receptor (betaAR) signaling are primarily due to the beta(1)AR subtype. beta(1)/beta(2)AR and beta(1)/adenylyl cyclase type 5 (AC5) bitransgenic mice were created to test the hypothesis that beta(2)AR or AC5
Autor:
Charles G. Irvin, Stephen B. Liggett, Kelan G. Tantisira, John J. Lima, Deborah A. Meyers, Eugene R. Bleecker, Stephen P. Peters, Qing Ling Duan, Brigitte R. Gaume, John P. Hanrahan, Blanca E. Himes, Gregory A. Hawkins, Barbara J. Klanderman, Augusto A. Litonjua
Publikováno v:
American journal of respiratory and critical care medicine. 183(4)
β₂-agonists, the most common treatment for asthma, have a wide interindividual variability in response, which is partially attributed to genetic factors. We previously identified single nucleotide polymorphisms in the arginase 1 (ARG1) gene, which
The β1-adrenergic receptor (β1AR; ADRB1) polymorphism Arg389Gly is located in an intracellular loop and is associated with distinct human and mouse cardiovascular phenotypes. To test the hypothesis that β1-Arg389 and β1-Gly389 alleles could diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8857647e26ef22823b07405aa3cecf
https://europepmc.org/articles/PMC2536824/
https://europepmc.org/articles/PMC2536824/