Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Brigitte Obermaier"'
Autor:
Andreas Eisenhardt, Kurt Werner Schmid, Kathrin Riemann, Brigitte Obermaier, Henrike Struwe, Winfried Siffert
Publikováno v:
Pharmacogenetics and Genomics. 18:999-1008
PURPOSE Polymorphisms in genes encoding subunits of heterotrimeric G proteins have been repeatedly associated with various cancers. As G beta gamma signaling is presumed to be involved in proliferation and invasion processes, we analyzed genetic vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34c81550bf31953f080d2d1000e8d8f
https://doi.org/10.1097/fpc.0b013e3283117d79
https://doi.org/10.1097/fpc.0b013e3283117d79
Autor:
Stefan Wiemann, Brigitte Obermaier, Stefan Bauersachs, Bernd Weil, Bernhard Korn, Michael Böcher, Michaela Klein, Wilhelm Ansorge, Dagmar Heubner, Hans-Werner Mewes, Sabine Glassl, Jürgen Lauber, Birgit Ottenwälder, Karl Köhrer, R. Wambutt, Andreas Beyer, Ruth Wellenreuther, Helmut Blum, A. Düsterhöft, Jens Tampe, Johannes Gassenhuber, Helmut Blöcker, Normann Strack, Annemarie Poustka
Publikováno v:
Genome Research. 11:422-435
With the complete human genomic sequence being unraveled, the focus will shift to gene identification and to the functional analysis of gene products. The generation of a set of cDNAs, both sequences and physical clones, which contains the complete a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419dfdcdab4b8c5e47faa389a77dd1f4
https://doi.org/10.1101/gr.154701
https://doi.org/10.1101/gr.154701
Autor:
Reinhold P. Linke, Klaus Denzel, Pia Winter, Dieter E. Jenne, Klaus Altland, Petra Blatzinger, Brigitte Obermaier
Publikováno v:
Proceedings of the National Academy of Sciences. 93:6302-6307
The most frequent form of inherited amyloidoses is associated with mutations in the transthyretin (TTR) gene coding for 127-amino acid residues of four identical, noncovalently linked subunits that form a pair of dimers in the plasma protein complex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0ab3a5e8d77ae66f0ff4052cb7b013
https://doi.org/10.1073/pnas.93.13.6302
https://doi.org/10.1073/pnas.93.13.6302
Publikováno v:
Yeast. 11:1103-1112
We report the sequence analysis of a 78,601 bp DNA segment on the left arm of chromosome II of Saccharomyces cerevisiae. This 78·6 kb segment spans the region from the start of a subtelomeric Y′ element up to the ILS1 gene. It contains 49 open rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdc5a0dddea9e17bc252c5ec3040591b
https://doi.org/10.1002/yea.320111112
https://doi.org/10.1002/yea.320111112
Autor:
Ernst J.M. Helmreich, Petra H. Bauer, Stefan Müller, Mechthild Puzicha, Martin J. Lohse, Brigitte Obermaier, Susanne Pippig
Publikováno v:
Nature. 358:73-76
Signal transduction by G-protein-coupled receptors is regulated by various mechanisms acting at the receptor level; those studied most thoroughly are from the beta-adrenergic receptor/Gs/adenylyl cyclase system. We report here a regulatory mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47136865fa2552ae40e07aabe2f27ceb
https://doi.org/10.1038/358073a0
https://doi.org/10.1038/358073a0
Autor:
Kathrin, Riemann, Henrike, Struwe, Hakan, Alakus, Brigitte, Obermaier, Klaus J, Schmitz, Kurt W, Schmid, Winfried, Siffert
Publikováno v:
Anticancer research. 29(4)
Polymorphisms in genes encoding subunits of heterotrimeric G proteins have been repeatedly associated with the course of cancer. As previously shown, intron 1 of GNB4 harbours distinct haplotype blocks and block 1 is associated with survival and dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e05e73392da6161bfa18c48746a4c15
https://pubmed.ncbi.nlm.nih.gov/19414374
https://pubmed.ncbi.nlm.nih.gov/19414374
Autor:
Heidi Rossmann, Ursula Seidler, Seth L. Alper, Alan K. Stuart-Tilley, Oliver Bachmann, Gary E. Shull, Brigitte Obermaier, Zhuo Wang
Publikováno v:
The Journal of physiology. 534(Pt 3)
1. The anion exchanger isoform 2 (AE2) gene encodes three subtypes (AE2a, b and c), which have different N-termini and tissue distributions. AE2 is expressed at high levels in the stomach, where it is thought to mediate basolateral base exit during a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae905c27b8f15485f71859c5bb6254b
https://pubmed.ncbi.nlm.nih.gov/11483713
https://pubmed.ncbi.nlm.nih.gov/11483713
Publikováno v:
Science (New York, N.Y.). 274(5290)
Entry into anaphase and proteolysis of B-type cyclins depend on a complex containing the tetratricopeptide repeat proteins Cdc16p, Cdc23p, and Cdc27p. This particle, called the anaphase-promoting complex (APC) or cyclosome, functions as a cell cycle-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9725ce83bd2b5f9cce331762db0a89
https://pubmed.ncbi.nlm.nih.gov/8895471
https://pubmed.ncbi.nlm.nih.gov/8895471
Publikováno v:
Insect biochemistry and molecular biology. 25(3)
Epidermal mRNA of freshly ecdysed pupae of Galleria mellonella was used to establish a cDNA library in phage lambda gtll. A cDNA clone was isolated by means of a pupal cuticle protein (PCP) specific antibody. Nucleic acid sequence data show an insert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49697033af2f9dfe7e52e856c2efb9e
https://pubmed.ncbi.nlm.nih.gov/7773255
https://pubmed.ncbi.nlm.nih.gov/7773255
Autor:
Dieter E. Jenne, Peter Lichter, Hartmut Wekerle, Thomas M. Fink, Michael Zimmer, Daniel Pilat, Brigitte Obermaier-Skrobanek
Publikováno v:
Genomics. 24(3)
Cosmid clones containing the genes for the human and murine natural killer cell serine protease Met-ase (gene symbol GZMM; granzyme M) were identified by screening human and murine cosmid libraries with rat Met-ase (RNK-Met-1) cDNA. The human gene ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c29c3d31da2ee69b6f25aa67594f715
https://pubmed.ncbi.nlm.nih.gov/7713495
https://pubmed.ncbi.nlm.nih.gov/7713495