Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Brigitte Marian"'
Autor:
Lisa Gabler, Carola Nadine Jaunecker, Sonja Katz, Sushilla van Schoonhoven, Bernhard Englinger, Christine Pirker, Thomas Mohr, Petra Vician, Mirjana Stojanovic, Valentin Woitzuck, Anna Laemmerer, Dominik Kirchhofer, Lisa Mayr, Mery LaFranca, Friedrich Erhart, Sarah Grissenberger, Andrea Wenninger-Weinzierl, Caterina Sturtzel, Barbara Kiesel, Alexandra Lang, Brigitte Marian, Bettina Grasl-Kraupp, Martin Distel, Julia Schüler, Johannes Gojo, Michael Grusch, Sabine Spiegl-Kreinecker, Daniel J. Donoghue, Daniela Lötsch, Walter Berger
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Glioblastoma (GBM) is characterized by a particularly invasive phenotype, supported by oncogenic signals from the fibroblast growth factor (FGF)/ FGF receptor (FGFR) network. However, a possible role of FGFR4 remained elusive so far. Several
Externí odkaz:
https://doaj.org/article/a09b2bdbe34d4252a9676846e4f372c1
Autor:
Daniel Drev, Andrea Bileck, Zeynep N. Erdem, Thomas Mohr, Gerald Timelthaler, Andrea Beer, Christopher Gerner, Brigitte Marian
Publikováno v:
Clinical Proteomics, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background Cancer associated fibroblasts are activated in the tumor microenvironment and contribute to tumor progression, angiogenesis, extracellular matrix remodeling, and inflammation. Methods To identify proteins characteristic for fibrob
Externí odkaz:
https://doaj.org/article/b0af78978365402a84965ee5fe984106
Autor:
Zeynep N. Erdem, Stefanie Schwarz, Daniel Drev, Christine Heinzle, Andrea Reti, Petra Heffeter, Xenia Hudec, Klaus Holzmann, Bettina Grasl-Kraupp, Walter Berger, Michael Grusch, Brigitte Marian
Publikováno v:
Translational Oncology, Vol 10, Iss 3, Pp 332-339 (2017)
BACKGROUND: Irinotecan (IRI) is an integral part of colorectal cancer (CRC) therapy, but response rates are unsatisfactory and resistance mechanisms are still insufficiently understood. As fibroblast growth factor receptor 3 (FGFR3) mediates essentia
Externí odkaz:
https://doaj.org/article/ad7b73d6acc34f24a8adc7e89f31908a
Autor:
Eva Mittermair, Hanspeter Kählig, Ammar Tahir, Stefanie Rindler, Xenia Hudec, Hemma Schueffl, Petra Heffeter, Brigitte Marian, Liselotte Krenn
Publikováno v:
Molecules, Vol 25, Iss 19, p 4449 (2020)
The tree fern Metaxya rostrata (Kunth) C. Presl is common in the rainforests of Central and South America, where suspensions of the dried rhizome are traditionally used to treat intestinal diseases. Two compounds from this plant, 2-deprenyl-rheediaxa
Externí odkaz:
https://doaj.org/article/8f05f046c3644d25a27b7a1ccf14c631
Autor:
Klaus Holzmann, Brigitte Marian
Publikováno v:
Cells, Vol 8, Iss 10, p 1191 (2019)
Fibroblast growth factors (FGFs) are a large family of protein ligands that exert a wide range of biological effects in many organs/tissues by activating receptors (FGFRs) of the tyrosine kinase superfamily [...]
Externí odkaz:
https://doaj.org/article/f538069d8d414b498ece8bf0691d9d8f
Autor:
Gerd Jomrich, Xenia Hudec, Felix Harpain, Daniel Winkler, Gerald Timelthaler, Thomas Mohr, Brigitte Marian, Sebastian F. Schoppmann
Publikováno v:
Cells, Vol 8, Iss 9, p 1092 (2019)
Even though distinctive advances in the field of esophageal cancer therapy have occurred over the last few years, patients’ survival rates remain poor. FGF8, FGF18, and FGFR4 have been identified as promising biomarkers in a number of cancers; howe
Externí odkaz:
https://doaj.org/article/c922ee05a09d4004bc6b24647d59d78a
Autor:
Amra Ibric, Stefan Eckerstorfer, Martin Eder, Ivan Louko, Leopold Tunjic, Petra Heffeter, Hemma Henrike Schueffl, Brigitte Marian, Norbert Haider
Publikováno v:
Molecules, Vol 24, Iss 4, p 716 (2019)
Following two orthogonal synthetic routes, a series of all four possible A-ring amino derivatives of the natural product Luotonin A (a known Topoisomerase I inhibitor) was synthesized. In both strategies, intramolecular cycloaddition reactions are th
Externí odkaz:
https://doaj.org/article/80c995a3d3054fce898f6d6e41e7b694
Publikováno v:
Molecules, Vol 22, Iss 9, p 1540 (2017)
An oxidative ring opening reaction of the central ring C in the alkaloid Luotonin A and two of its derivatives was found to occur upon heating with an excess amine and potassium carbonate in dimethylsulfoxide (DMSO) solution in the presence of air ox
Externí odkaz:
https://doaj.org/article/2c7eaf6c2ed04975ad0c20eb8350a7fd
Autor:
David M Baron, Ulrike Kaindl, Verena J Haudek-Prinz, Editha Bayer, Clemens Röhrl, Christopher Gerner, Brigitte Marian
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114158 (2014)
Colorectal cancer is a leading cause of mortality worldwide. Resistance to therapy is common and often results in patients succumbing to the disease. The mechanisms of resistance are poorly understood. Cells basically have two possibilities to surviv
Externí odkaz:
https://doaj.org/article/3282565958db4a688284c21b482f5d70
Autor:
Kerstin P. Kainz, Liselotte Krenn, Zeynep Erdem, Hanspeter Kaehlig, Martin Zehl, Wilfried Bursch, Walter Berger, Brigitte Marian
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/eaca1eea45784254937be682a4c0e26c